Results 111 to 120 of about 540,208 (312)

Proteomic approach to profiling immune complex antigens in cerebrospinal fluid samples from patients with central nervous system autoimmune diseases [PDF]

, 2018
Background: Immune complexes (ICs) may clearly reflect immunological abnormalities caused by disease, especially for autoimmune diseases. Although ICs have been detected in cerebrospinal fluid (CSF) from patients with CNS autoimmune diseases, identities ...
Kawakami, Atsushi, Nozomi Aibara, Miyako Baba, Naotaka Kuroda, Hideki Nakajima, Ryuichiro Atarashi, Satoh, Katsuya, Kuroda, Naotaka, Nishida, Noriyuki, Ohyama, Kaname, Atarashi, Ryuichiro, Atsushi Kawakami, Kaname Ohyama, Baba, Miyako, Katsuya Satoh, Nakajima, Hideki, Kishikawa, Naoya, Naoya Kishikawa, Noriyuki Nishida, Ichinose, Kunihiro, Aibara, Nozomi, Kunihiro Ichinose   +21 more
core   +1 more source

Persistent Bilateral [18F]THK5351 and Migrating Unilateral [18F]FDG Uptake in Anti‐LGI1 Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Anti–leucine‐rich glioma‐inactivated 1 encephalitis (LGI1‐E) can cause persistent cognitive deficits, but the mechanisms remain unclear. A 40‐year‐old woman with LGI1‐E presented with subacute cognitive deficits and showed mild left medial temporal lobe (MTL) swelling and fluid‐attenuated inversion recovery (FLAIR) hyperintensity on initial ...
Yusuke Akitomi, Kenichiro Taira, Masanori Kurihara, Kenji Ishibashi, Kenji Ishii, Fumio Suzuki, Aya Midori Tokumaru, Makoto Hara, Atsushi Iwata   +8 more
wiley   +1 more source

Predictors of mortality in hospitalised patients with COVID-19: a 1-year case–control study

BMJ Open
Background A paucity of predictive models assessing risk factors for COVID-19 mortality that extend beyond age and gender in Latino population is evident in the current academic literature.Objectives To determine the associated factors with mortality, in
Juan-Manuel Anaya, Diana M Monsalve, Yeny Acosta-Ampudia, Carolina Ramírez-Santana, Santiago Garcia, Laura Camacho-Domínguez, Manuel Rojas, María Herrán, Yhojan Rodríguez, Santiago Beltrán, Paola Saboya Galindo, Nicolas Aguirre-Correal, María Espitia, Valeria Bejarano, Victoria Morales-González, Jaime Enrique Covaleda-Vargas, Mónica Rodríguez-Jiménez, Elizabeth Zapata   +17 more
doaj   +1 more source

Genomics and proteomics: Applications in autoimmune diseases

, 2009
Wolfgang Hueber1,2,3, William H Robinson1,21VA Palo Alto Health Care System, Palo Alto, CA, USA; 2Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA; 3Novartis Institutes of Biomedical Research, Novartis ...
Wolfgang Hueber, William H Robinson
core  

Autoimmune Pathogenesis, Related Diseases and Laboratories

, 2021
The immune system is a complex system that forms the defense mechanism against diseases in a living thing, recognizes and destroys pathogens and tumor cells, and protects the body from foreign and harmful substances.
Yurtcu, Nazan, Demir, Kenan
core  

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Contemporary concepts of autoimmunity and autoimmune diseases

Journal of Clinical Laboratory Analysis, 1992
No single theory or mechanism can explain the phenomenon of autoimmunity and autoimmune diseases. Not all autoimmune responses are harmful or "forbidden." Considerable research has indicated that autoimmune response may be normal and important in the regulation of the immune system.
M C, Nakamura, R M, Nakamura
openaire   +2 more sources

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Eosinophilia and Risk of Thrombosis and Mortality in Hospitalized Patients: A Retrospective Cohort Study

Life
Background: Eosinophilia, defined as peripheral blood eosinophil counts > 0.5 K/μL, is associated with various clinical conditions, including allergic, infectious, and malignant diseases.
Ronen Shavit, Adi Kidron, Ramit Maoz Segal, Stanley Niznik, Soad Haj Yahia, Mona Iancovici-Kidon, Irena Offengenden, Diti Machnes Maayan, Yulia Lifshitz-Tunitsky, Liraz Olmer, Nancy Agmon-Levin   +10 more
doaj   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source