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Autoimmune liver disease and concomitant extrahepatic autoimmune disease
European Journal of Gastroenterology & Hepatology, 2015To assess the frequency and clinical impact of associated extrahepatic autoimmune diseases (EAD) on autoimmune liver diseases (ALD).We investigated 608 patients with ALD (327 autoimmune hepatitis - AIH and 281 primary biliary cirrhosis - PBC) for concomitant EAD.In both AIH and PBC, we observed a high prevalence of EAD (29.9 and 42.3%, respectively ...
MURATORI, PAOLO +4 more
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Autoimmunity in Demyelinating Diseases
Annals of the New York Academy of Sciences, 1987Demyelinative diseases of the CNS and peripheral nervous system can be distinguished on the basis of primary mediation by antibody or T lymphocytes (or failure of the T-cell-mediated response) and on the basis of chronicity. The principal mechanisms are autoimmunization to myelin antigens after actual immunization with tissue or infection with cross ...
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Autoimmunity in obstetrics and autoimmune diseases in pregnancy
Best Practice & Research Clinical Obstetrics & Gynaecology, 2019Autoimmune diseases (AIDs) are associated with strong female preponderance and often present before or during the reproductive years; consequently, pregnancy and breastfeeding are topics of major interest for these patients. AIDs show different responses to pregnancy: some ameliorate, while others remain unchanged, and several AIDs aggravate.
De Carolis, Sara +7 more
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2010
Primary adrenocortical insufficiency, or Addison's disease (AD), results from an adrenal cortex hypofunction/dysfunction with a deficient production of glucocorticoids, mineralocorticoids and androgens, and with high levels of both ACTH and plasma renin activity.
BETTERLE, CORRADO, MORLIN L.
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Primary adrenocortical insufficiency, or Addison's disease (AD), results from an adrenal cortex hypofunction/dysfunction with a deficient production of glucocorticoids, mineralocorticoids and androgens, and with high levels of both ACTH and plasma renin activity.
BETTERLE, CORRADO, MORLIN L.
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Autoimmunity in Neuromuscular Disease
Annals of the New York Academy of Sciences, 1987SUMMARY AND CONCLUSIONSA number of confounding factors can be identified from the search for autoimmune mechanisms over the last 2 decades that may be relevant for future studies. (1) An apparently homogeneous clinical disorder may represent more than one disease process and thereby imply antibody/antigen heterogeneity as, for example, in MG with and ...
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Immunoregulation of Autoimmune Diseases
Human Immunology, 2006Since the discovery of human leukocyte antigen (HLA) as a genetic system, the search for the biological function of HLA molecules has been a very intense and attractive area of immunological research. It has been a major factor in the development of our understanding of the role of T cells in the initiation and regulation of autoimmune diseases.
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Stress Proteins, Autoimmunity, and Autoimmune Disease
1991At birth, the immune system is biased toward recognition of microbial antigens in order to protect the host from infection. Recent data suggest that an important initial line of defense in this regard involves autologous stress proteins, especially conserved peptides of hsp60, which are presented to T cells bearing gamma delta receptors by relatively ...
J B, Winfield, W N, Jarjour
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[Autoimmunization and autoimmune diseases].
Arkhiv patologii, 1992Autoimmunization is understood as a type of immune reactions to the unchanged autoantigens only. Autoimmune processes can be subdivided into the physiological ("sanitary" and regulatory) and pathological ones. Physiological processes are of importance in supporting natural immunological tolerance while pathological processes develop on the basis of the
V V, Serov, O V, Zaĭrat'iants
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