Results 81 to 90 of about 542,591 (214)

Autoimmunity and autoimmune disease [PDF]

Nephrology Dialysis Transplantation, 2001
Katsorida, ME, Moutsopoulos, HM
openaire   +3 more sources

[Diagnostics of autoimmune diseases] [PDF]

, 2008
Autoantibodies play a key role in diagnostic laboratories as markers of autoimmune diseases. In addition to their role as markers they mediate diverse effects in vivo. Autoantibodies with protective effect have been described.
Beleznay, Zsuzsanna, Regenass, Stephan
core  

Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus. [PDF]

, 2011
The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes.
Mantovani Alberto, Heni Eka Susanti, Adriana Migliorini, A. Migliorini, Susanti, Heni Eka, Hans-Joachim Anders, Christoph Römmele, Kulkarni, Onkar P., M. Lech, Cecilia Garlanda, Kulkarni Onkar P., Lech, Maciej, Lech Maciej, Garlanda Cecilia, C. Garlanda, Römmele, Christoph, Migliorini Adriana, Mantovani, Alberto, Alberto Mantovani, Anders Hans-Joachim, Onkar P Kulkarni, Maciej Lech, Susanti Heni Eka, A. Mantovani, Anders, Hans-Joachim, Römmele Christoph, H.E. Susanti, Migliorini, Adriana, O.P. Kulkarni, C. Römmele, H. J. Anders, Garlanda, Cecilia, Onkar P. Kulkarni   +32 more
core   +1 more source

Oleic acid alleviates the pathogenesis of lupus by suppressing the activation of TLR signaling pathways through the STAT3/IL-10 axis

Scientific Reports
Toll-like receptors (TLRs) play a pivotal role in the pathogenesis of systemic lupus erythematosus (SLE) by regulating the activation and differentiation of immune cells. Oleic acid (OA), the predominant monounsaturated fatty acid found in adipose tissue,
Yuxin Hu, Yucai Xiao, Yangzhe Gao, Zhengyi Zhang, Tianqi Zhao, Shuo Zhao, Jiakun Liu, Huabao Xiong, Yonghong Yang, Guanjun Dong, Lu Yu   +10 more
doaj   +1 more source

Chapter 30 - Autoimmune thyroid diseases [PDF]

Autoimmune thyroid diseases include chronic autoimmune thyroiditis (CAT) with its variants and Graves’ disease (GD). Both disorders have a genetic predisposition, but existential and environmental factors play a relevant role in their development.
Luigi Bartalena, Daniela Gallo, Maria Laura Tanda   +2 more
core   +1 more source

Analysis of IL2/IL21 Gene Variants in Cholestatic Liver Diseases Reveals an Association with Primary Sclerosing Cholangitis [PDF]

, 2011
Background/Aims: The chromosome 4q27 region harboring IL2 and IL21 is an established risk locus for ulcerative colitis (UC) and various other autoimmune diseases.
Denk, Gerald Ulrich, Brand, Stephan, Burkhard Göke, Göke, Burkhard, Stephan Brand, Rüdiger Paul Laubender, Christian Rust, Johannes Stallhofer, Jürgen Glas, Laubender, Rüdiger Paul, Glas, Jürgen, Pusl, Thomas, Thomas Pusl, Gerald Ulrich Denk, Stallhofer, Johannes, Rust, Christian   +15 more
core   +1 more source

Autoimmune Diseases in Humans, e.g. Autoimmune Rheumatic Diseases

Intervirology, 1993
In spite of increasing evidence that viruses and especially retroviruses could act as etiologic factors in autoimmune and especially autoimmune rheumatic diseases, clear-cut evidence for an involvement of these agents is still missing. Findings, which, for example, indirectly support the hypothesis that retroviruses might play a part, are the ...
J R, Kalden, M, Herrmann
openaire   +2 more sources

Proteomic approach to profiling immune complex antigens in cerebrospinal fluid samples from patients with central nervous system autoimmune diseases [PDF]

, 2018
Background: Immune complexes (ICs) may clearly reflect immunological abnormalities caused by disease, especially for autoimmune diseases. Although ICs have been detected in cerebrospinal fluid (CSF) from patients with CNS autoimmune diseases, identities ...
Kawakami, Atsushi, Nozomi Aibara, Miyako Baba, Naotaka Kuroda, Hideki Nakajima, Ryuichiro Atarashi, Satoh, Katsuya, Kuroda, Naotaka, Nishida, Noriyuki, Ohyama, Kaname, Atarashi, Ryuichiro, Atsushi Kawakami, Kaname Ohyama, Baba, Miyako, Katsuya Satoh, Nakajima, Hideki, Kishikawa, Naoya, Naoya Kishikawa, Noriyuki Nishida, Ichinose, Kunihiro, Aibara, Nozomi, Kunihiro Ichinose   +21 more
core   +1 more source

Long-term efficacy and safety of the Lupus-Cruces Nephritis protocol: a propensity score study of the Lupus-Cruces and Lupus-Bordeaux cohorts

Lupus Science and Medicine
Objective To assess the efficacy and toxicity of the Lupus-Cruces Nephritis (LCN) protocol compared with standard of care (SOC) with cyclophosphamide (CYC) or mycophenolate in patients with lupus nephritis (LN) during an extended follow-up time up to 10 ...
Guillermo Ruiz-Irastorza, Estibaliz Lazaro, Beatriz Marín-García, Luis Dueña-Bartolomé, Diana Paredes Ruiz, Amaia Osorio   +5 more
doaj   +1 more source

Predictors of mortality in hospitalised patients with COVID-19: a 1-year case–control study

BMJ Open
Background A paucity of predictive models assessing risk factors for COVID-19 mortality that extend beyond age and gender in Latino population is evident in the current academic literature.Objectives To determine the associated factors with mortality, in
Juan-Manuel Anaya, Diana M Monsalve, Yeny Acosta-Ampudia, Carolina Ramírez-Santana, Santiago Garcia, Laura Camacho-Domínguez, Manuel Rojas, María Herrán, Yhojan Rodríguez, Santiago Beltrán, Paola Saboya Galindo, Nicolas Aguirre-Correal, María Espitia, Valeria Bejarano, Victoria Morales-González, Jaime Enrique Covaleda-Vargas, Mónica Rodríguez-Jiménez, Elizabeth Zapata   +17 more
doaj   +1 more source