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Autoimmune hemolytic anemia in adults: primary risk factors and diagnostic procedures
Expert Review of Hematology, 2020Introduction Autoimmune hemolytic anemia (AIHA) is due to autoantibodies against erythrocytes that may arise either because of primary tolerance breakage or along with several associated conditions, including genetic predispositions, congenital syndromes,
W. Barcellini, J. Giannotta, B. Fattizzo
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Pediatric Clinics of North America, 1980
In autoimmune hemolytic anemia, individuals produce antibodies directed against one of their own erythrocyte membrane antigens. The hemolysis in autoimmune hemolytic anemia is most commonly extravascular rather than intravascular, and the liver and spleen play a major role in the clearance of the antibody-coated cells.
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In autoimmune hemolytic anemia, individuals produce antibodies directed against one of their own erythrocyte membrane antigens. The hemolysis in autoimmune hemolytic anemia is most commonly extravascular rather than intravascular, and the liver and spleen play a major role in the clearance of the antibody-coated cells.
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Human Pathology, 1983
Nowhere in the management of patients with autoimmune hemolytic anemias is the communication between clinician and laboratory personnel more important than in regard to blood transfusion. A clinical decision that blood transfusion is necessary must be tempered by the knowledge that transfusion has a greater-than-usual risk in this setting, both because
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Nowhere in the management of patients with autoimmune hemolytic anemias is the communication between clinician and laboratory personnel more important than in regard to blood transfusion. A clinical decision that blood transfusion is necessary must be tempered by the knowledge that transfusion has a greater-than-usual risk in this setting, both because
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Autoimmune Pathogenesis and Autoimmune Hemolytic Anemia
Seminars in Hematology, 2005Autoimmune hemolytic anemia (AIHA) is an autoimmune disorder in which autoantibodies are directed against an individual's own red blood cells (RBCs), leading to enhanced clearance through Fc receptor (FcR)-mediated phagocytosis. Although there is a large literature relating to clinical aspects of AIHA, relatively little work addresses how IgG ...
John Freedman, John W. Semple
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Archives of Internal Medicine, 1975
Warm-type autoantibodies of autoimmune hemolytic anemia (AIHA) are usually IgG but may be IgM or IgA. They are usual Rh specific. Cold-type antibodies are IgM or IgG (Donath-Landsteiner [DL] antibody). IgM antibodies are usually anit-l (occasionally anti-i) and DL antibodies anti-P.
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Warm-type autoantibodies of autoimmune hemolytic anemia (AIHA) are usually IgG but may be IgM or IgA. They are usual Rh specific. Cold-type antibodies are IgM or IgG (Donath-Landsteiner [DL] antibody). IgM antibodies are usually anit-l (occasionally anti-i) and DL antibodies anti-P.
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Hospital Practice, 1985
Rh and ABO incompatibilities, drug reactions, and lupus are a few of the many causes of autoimmune hemolytic anemia. Among the determinants of autoimmunity involved are the class of the antibody, the biochemical composition of the antigen, the distribution of the antigen on the erythrocyte membrane, and the effector cells and molecules that are ...
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Rh and ABO incompatibilities, drug reactions, and lupus are a few of the many causes of autoimmune hemolytic anemia. Among the determinants of autoimmunity involved are the class of the antibody, the biochemical composition of the antigen, the distribution of the antigen on the erythrocyte membrane, and the effector cells and molecules that are ...
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Complications of Autoimmune Hemolytic Anemia
Hematology/Oncology Clinics of North America, 2022Autoimmune hemolytic anemia (AHIA) is the group of acquired autoimmune conditions resulting from the development of autologous antibodies directed against autologous red blood cell antigens resulting in red cell lysis. Beyond the presence, severity, and duration of hemolysis which can lead to symptomatic anemia, additional complications at presentation
Surbhi, Shah, Leslie, Padrnos
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Autoimmune hemolytic anemia: A history*
Transfusion Medicine Reviews, 2000UTOIMMUNE HEMOLYTIC anemia (AIHA) is an acquired immunoIogic disease in which the patient's red blood cells (RBCs) are selectively attacked and destroyed (hemolyzed) by autoantibodies produced by the patient's own immune system. These patients generally display the common symptoms of anemia: weakness, pallor, fatigue, and jaundice.
John Freedman, Peter Mack
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Autoimmune Hemolytic Anemia and Cancer [PDF]
JAMA: The Journal of the American Medical Association, 1965 THE OCCURRENCE of overt hemolytic anemia in malignant diseases other than those involving the reticuloendothelial system is uncommon. Approximately 15 cases of overt hemolytic anemia associated with cancer have been reported in the medical literature.
Lawrence D. Ellis, Maxwell P. Westerman
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Autoimmune Hemolytic Anemia in Scleroderma
JAMA: The Journal of the American Medical Association, 1971In a case of scleroderma and autoimmune hemolytic anemia, azathioprine treatment resulted in complete remission of the hemolysis despite the persistence of positive direct and indirect antiglobulin test. There were no beneficial results of the therapy on the underlying connective tissue disorder. Complications of azathioprine treatment encountered were
Burton Sack, David S. Rosenthal
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