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AUTOIMMUNE HEMOLYTIC ANEMIA IN CHILDREN
Pediatric Hematology and Oncology, 2007The clinical and hematological profile and treatment outcome of children with warm autoimmune hemolytic anemia (AIHA) were assessed using retrospective case record analysis. There were 26 (17 idiopathic; 9 secondary) patients with a median age of 11 years. Pallor (100%), fever (39%), and jaundice (59%) were the main presenting complaints.
Ved Prakash Choudhry +5 more
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Geoepidemiology of autoimmune hemolytic anemia
Autoimmunity Reviews, 2010Autoantibodies against red blood cell antigens are considered the diagnostic hallmark of AIHA: Direct antiglobulin test (DAT) completed by cytofluorometry and specific diagnostic monoclonal antibodies (mAbs) allow for a better understanding of autoimmune hemolytic anemia (AIHA) triggers. Once B-cell tolerance checkpoints are bypassed, the patient loses
Urs E. Nydegger, Jean-Francois Lambert
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Autoimmunization and the Autoimmune Hemolytic Anemias
JAMA: The Journal of the American Medical Association, 1969This is an unusual book in both concept and presentation. The first half presents the problem of autoimmune hemolytic anemias in a clinical perspective. Material from the vast literature is interwoven with a very substantial personal clinical experience, more than 200 cases, that the author observed during an eight-year period.
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Treatment of Autoimmune Hemolytic Anemia
Seminars in Hematology, 2005The appropriate therapy of autoimmune hemolytic anemia (AIHA) is dependent on the correct diagnosis and classification of this family of hemolytic disorders. Although the majority of cases are warm AIHA, there are several distinct types of cold AIHA and a number of drug-induced etiologies of AIHA, which must be investigated to determine if stopping a ...
Paul M. Ness, Karen E. King
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European Journal of Haematology, 2018
Immune checkpoint inhibitors (CPI) are widely used in modern oncology and have improved the prognosis of lung cancer, malignant melanoma, and other malignancies.
Georges E. Tanios +2 more
semanticscholar +1 more source
Immune checkpoint inhibitors (CPI) are widely used in modern oncology and have improved the prognosis of lung cancer, malignant melanoma, and other malignancies.
Georges E. Tanios +2 more
semanticscholar +1 more source
2009
Publisher Summary This chapter reviews autoimmune hemolytic anemias (AIHA) which includes a group of disorders where autoantibodies are directed against red blood cell (RBC) membrane antigens. This results in shortened RBC survival through activation of the complement system and removal within the reticuloendothelial system.
Christopher D. Hillyer, Beth H. Shaz
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Publisher Summary This chapter reviews autoimmune hemolytic anemias (AIHA) which includes a group of disorders where autoantibodies are directed against red blood cell (RBC) membrane antigens. This results in shortened RBC survival through activation of the complement system and removal within the reticuloendothelial system.
Christopher D. Hillyer, Beth H. Shaz
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Archives of Internal Medicine, 1977
Autoimmune hemolytic anemia (AHA) may be either primary (ie, "idiopathic," one third of all patients) or secondary (ie, associated with underlying illness, two thirds of all patients). A positive Coombs antiglobulin test is the most important criterion for diagnosis of AHA, and characterization of RBC coating (as to whether it is by IgG alone, by IgG ...
Hugh Chaplin, Louis V. Avioli
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Autoimmune hemolytic anemia (AHA) may be either primary (ie, "idiopathic," one third of all patients) or secondary (ie, associated with underlying illness, two thirds of all patients). A positive Coombs antiglobulin test is the most important criterion for diagnosis of AHA, and characterization of RBC coating (as to whether it is by IgG alone, by IgG ...
Hugh Chaplin, Louis V. Avioli
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Warm Autoimmune Hemolytic Anemia
Hematology/Oncology Clinics of North America, 2015Warm autoimmune hemolytic anemia (AIHA) is defined as the destruction of circulating red blood cells (RBCs) in the setting of anti-RBC autoantibodies that optimally react at 37°C. The pathophysiology of disease involves phagocytosis of autoantibody-coated RBCs in the spleen and complement-mediated hemolysis.
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Autoimmune Hemolytic Anemia in a Dog
Journal of the American Veterinary Medical Association, 1973SUMMARY Autoimmune hemolytic anemia (aha) occurred in a 3½-year-old Cocker Spaniel. The clinical signs and blood values on initial examination were consistent with a diagnosis of aha; however, the results of Coombs’ antiglobulin test were not conclusive until 7 months later.
M D, Avolt, J E, Lund, J C, Pickett
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Seminars in hematology (Print), 2018
The classical complement pathway and, to some extent, the terminal pathway, are involved in the immune pathogenesis of autoimmune hemolytic anemia (AIHA).
S. Berentsen
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The classical complement pathway and, to some extent, the terminal pathway, are involved in the immune pathogenesis of autoimmune hemolytic anemia (AIHA).
S. Berentsen
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