Results 41 to 50 of about 173,185 (344)

Seronegative Autoimmune Hepatitis

open access: yesJournal of Clinical and Translational Hepatology, 2022
Autoimmune hepatitis (AIH) is a relatively rare liver disease with varying worldwide incidence of from 0.7 to 2 per 100,000 people. It is characterized by the presence of auto-antibodies. However, an average of 10% of AIH cases have AIH symptoms and pathology but lack autoimmune serology.
Sriya A. Bhumi, George Y. Wu
openaire   +2 more sources

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

Clinical Case of Autoimmune Hepatitis in 59-year-old Woman with Effective Treatment with Budesonide

open access: yesGastroenterologìa, 2013
Autoimmune hepatitis is a necroinflammatory liver disease of unknown etiology. According to the histology the disease is characterized by lobular hepatitis, in blood chemistry — increasing the level of aspartate aminotransferase and alanine ...
L.Ya. Melnychenko   +2 more
doaj   +1 more source

Antimitochondrial antibody -M2 positive autoimmune hepatitis during standard of care for chronic hepatitis C. [PDF]

open access: yes, 2012
The current standard of care (SoC) for chronic hepatitis C, i.e. the combination of a pegylated-interferon (PEG-IFN) with ribavirin (RBV), may activate underlying autoimmune conditions.
ALESSI, Nicola   +2 more
core   +1 more source

Health disparities in chronic liver disease

open access: yesHepatology, EarlyView., 2022
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian   +3 more
wiley   +1 more source

Autoimmune hepatitis type-2 and Epstein-Barr virus infection in a toddler: art of facts or an artifact?

open access: yesAnnals of Hepatology, 2013
Epstein-Barr virus (EBV) can cause frequently asymptomatic (or anicteric) and self-limited hepatitis, while occasionally may result in considerable cholestatic hepatitis.
Aglaia Zellos   +5 more
doaj   +1 more source

Immune Thrombocytopenia Associated with Hepatitis B Virus and Autoimmune Hepatitis and Recovery of Platelet Count following Liver Transplantation

open access: yesCase Reports in Transplantation, 2021
Immune thrombocytopenia is a consumptive coagulopathy that can be either idiopathic or associated with infectious or autoimmune etiologies. Here, we present a case of immune thrombocytopenia in the setting of acute liver failure due to coexisting ...
Chloe Nobuhara   +4 more
doaj   +1 more source

MAIT cells come to the rescue in cancer immunotherapy? [PDF]

open access: yes, 2020
Recent progress in immunobiology has led to the observation that, among cells classically categorized as the typical representatives of the adaptive immune system, i.e., T cells, some possess the phenotype of innate cells.
Elewaut, Dirk   +2 more
core   +2 more sources

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

open access: yesHepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger   +7 more
wiley   +1 more source

Association of STAT4 polymorphisms with susceptibility to type-1 autoimmune hepatitis in the Japanese population.

open access: yesPLoS ONE, 2013
Background/aimsRecent studies demonstrated an association of STAT4 polymorphisms with autoimmune diseases including systemic lupus erythematosus and rheumatoid arthritis, indicating multiple autoimmune diseases share common susceptibility genes.
Kiyoshi Migita   +34 more
doaj   +1 more source

Home - About - Disclaimer - Privacy