Results 91 to 100 of about 265,644 (234)

Risk of Pancreatic Cancer in Inflammatory Pancreatic Diseases

The Korean Journal of Gastroenterology
All known inflammatory diseases of the pancreas, i.e., acute, chronic, hereditary, and autoimmune pancreatitis, carry a higher risk of developing pancreatic cancer.
J.-Matthias Löhr, Miroslav Vujasinovic, Patrick Maisonneuve   +2 more
doaj   +1 more source

Chapter 42 - Autoimmune pancreatitis

Autoimmune pancreatitis (AIP) is a chronic inflammatory and fibrosing disease of the pancreas classified as Type 1 and Type 2 based on two distinct patterns of histopathologic and clinical presentation.
Barkin, Jodie A., Acosta, Camilo J., Kuker, Russ, Milano, Reza V.   +3 more
core   +1 more source

Autoimmune Chronic Pancreatitis

Journal of the Chinese Medical Association, 2008
Autoimmune pancreatitis (AIP) is a unique form of chronic pancreatitis that is characterized by swelling of the pancreas, narrowing of the main pancreatic duct (MPD), elevation of serum gamma globulin, or immunoglobulin G or presence of autoantibody, lymphoplasmacytic infiltration and dense fibrosis on histopathology.
Lin, Lien-Fu, Huang, Pi-Teh, Ho, Ka-Sic, Tung, Jai-Nien   +3 more
openaire   +2 more sources

European Consortium for Lipodystrophies consensus definition and classification framework for monogenic lipodystrophy

Journal of Internal Medicine, EarlyView.
Abstract Lipodystrophy comprises a heterogeneous group of disorders characterized by reduced adipose tissue often associated with severe metabolic complications. Lipodystrophy may be genetic, acquired, or secondary to medical therapies initiated for other conditions.
Robert K. Semple, Martin Wabitsch, Baris Akinci, Saif Alyaarubi, Marjoleine F. Broekema, Rebecca J. Brown, Giovanni Ceccarini, Carolina Cecchetti, Solaf M. Elsayed, Antía Fernández‐Pombo, Alessandra Gambineri, Ingrid M. Jazet, Lotte Kleinendorst, Konstanze Miehle, Elif A. Oral, Flavia Prodam, Ferruccio Santini, David B. Savage, Nadia Shaukat Ali, Ekaterina Sorkina, Magdalena Szopa, Marie‐Christine Vantyghem, Camille Vatier, Corinne Vigouroux, Julia von Schnurbein, David Araújo‐Vilar   +25 more
wiley   +1 more source

Chronic pancreatitis: a changing etiology or a gap in technological medicine

Emergency Care Journal, 2009
Alcohol is considered the most important risk factor for the development of chronic pancreatitis. The possibility of evaluating CFTR mutations and the discovery of other gene mutations has led to a better evaluation of the familiar/hereditary forms of ...
Raffaele Pezzilli, Lara Bellacosa, Bahajat Barakat   +2 more
doaj   +1 more source

Human cationic trypsinogen but not serine peptidase inhibitor, Kazal type 1 variants increase the risk of type 1 autoimmune pancreatitis

, 2017
Background and Aim: Autoimmune pancreatitis (AIP) is a distinct disease entity. Whether the genes involved in pancreatic acinar cell injury, cationic trypsinogen gene (protease, serine, 1 [trypsin 1] [PRSS1]) and the pancreatic secretory trypsin ...
Chang, Ming-Chu;Jan, I-Shiow;Liang, Po-Chin;Jeng, Yung-Ming;Yang, Ching-Yao;Tien, Yu-Wen;Wong, Jau-Min;Chang, Yu-Ting, 鄭永銘;詹一秀;翁昭旼;章明珠;田郁文;楊卿堯;張毓廷;梁博欽   +1 more
core   +1 more source

Autoimmune pancreatitis and cholangitis

World Journal of Gastrointestinal Pharmacology and Therapeutics, 2015
Autoimmune pancreatitis (AIP) is part of a systemic fibrosclerotic process characterized by lymphoplasmacytic infiltrate with immunoglobulin G subtype-4 (IgG4) positive cells. It characteristically presents with biliary obstruction due to mass-like swelling of the pancreas.
Niraj, Jani, James, Buxbaum
openaire   +2 more sources

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

Obesity Reviews, EarlyView.
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati, David Krongauz, Alice Bosco, Antonio Noto, Cristina Piras, Maria Kafyra, Angelica Dessì, Matteo Mauri, Luigi Atzori, Adina Weinberger, Vassilios Fanos, George V. Dedoussis, on behalf of the BETTER4U consortium   +12 more
wiley   +1 more source

R‐Loops Mediated Odontogenic Differentiation of hDPSCs by Activating the cGAS‐STING Pathway Under Inflammatory Microenvironment

Oral Diseases, EarlyView.
ABSTRACT Background R‐Loops are three‐stranded DNA/RNA hybrids implicated in immune responses. Their role in mesenchymal stem cell differentiation, particularly in dental pulp regeneration under inflammation, remains unclear. Methods Rat pulpo‐dentinal complex (PDC) injury models and LPS‐stimulated human dental pulp stem cells (hDPSCs) were used.
Yun Yang, Yiqing Wang, Yating Miao, Zhipu Luo, Lin Niu, Ruirui Liu   +5 more
wiley   +1 more source

Immunoglobulin G4-Related Pancreatic and Biliary Diseases

Canadian Journal of Gastroenterology, 2013
BACKGROUND: Autoimmune pancreatitis and autoimmune cholangitis are new clinical entities that are now recognized as the pancreaticobiliary manifestations of immunoglobulin (Ig) G4-related disease.
Hisham Al-Dhahab, Julia McNabb-Baltar, Said Al-Busafi, Alan N Barkun   +3 more
doaj   +1 more source