Results 91 to 100 of about 23,206 (196)

Pathophysiology of autoimmune pancreatitis

World Journal of Gastrointestinal Pathophysiology, 2014
Autoimmune pancreatitis (AIP) is a recently discovered form of pancreatitis and represents one of the diseases of the pancreas which can be cured and healed medically. International consensus diagnostic criteria have been developed, and the clinical phenotypes associated with the histopathologic patterns of lymphoplasmacytic sclerosing pancreatitis and
Raffaele, Pezzilli, Nico, Pagano
openaire   +2 more sources

Acute Pancreatitis and Splenic Infarction as Initial Symptoms of a Male Patient With SLE: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Systemic lupus erythematosus (SLE) can rarely present as concurrent acute pancreatitis (AP), splenic infarction, and renal failure. This case demonstrates that prompt diagnosis and immunosuppression are crucial for reversing organ damage—even in male patients, expanding the known clinical spectrum of this disease.
Jian‐mei Gong, Xu Jun
wiley   +1 more source

Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu, Usri H. Ibrahim, Irene Mackraj, Carola Niesler   +3 more
wiley   +1 more source

Necrotising pancreatitis in a patient with CREST syndrome: a rare autoimmune gastrointestinal complication

European Journal of Case Reports in Internal Medicine
Necrotising pancreatitis is a severe and life-threatening form of acute pancreatitis characterised by the necrosis of pancreatic and peripancreatic tissues due to intense inflammation and autodigestion.
Antonio Al Hazzouri, Philippe Attieh, George Ghaleb, Ahmad Khalil, Noura Chamchoum, Karam Karam, Elias Fiani   +6 more
doaj   +1 more source

Chronic ulcerative oesophagitis rich in IgG4‐positive plasma cells – a distinct clinicopathological entity

Histopathology, Volume 89, Issue 1, Page 47-57, July 2026.
We report a series of 12 patients (mean age 63 years) with chronic oesophageal ulceration showing morphological features of IgG4‐related inflammatory disease. Most patients underwent several rounds of endoscopy until this association was recognized. The majority of patients went into clinical and histological remission following corticosteroid therapy.
Hanna Henzinger, Ian Brown, Anthony J Gill, Tomas Slavik, Giuseppe Zamboni, Cord Langner   +5 more
wiley   +1 more source

Liver Injury From Medications Used for Treating Inflammatory Bowel Disease: The Drug‐Induced Liver Injury Network Experience

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background We aimed to investigate and characterise DILI due to approved therapies for inflammatory bowel disease (IBD). Methods Using the Drug‐Induced Liver Injury Network (DILIN) prospective study, we evaluated definite, highly likely, or probable DILI attributed to IBD therapies, including use for non‐IBD indications (but excluding ...
Harish Gopalakrishna, Jiezhun Gu, Yi‐Ju Li, Huiman Barnhart, Dina Halegoua‐DeMarzio, Herbert L. Bonkovsky, A. Sidney Barritt, Jean P. Molleston, Naga P. Chalasani, Marwan Ghabril   +9 more
wiley   +1 more source

A Three‐Step Diagnostic Strategy for Malignant Pleural Effusions

Cancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT New diagnostic tools, such as high fluorescence cells (HFc) and tumor markers (TMs), have emerged in the quest to accurately diagnose malignant pleural effusion (MPE). This study evaluated the diagnostic performance of the HFc and TMs combination.
Elisa Nuez‐Zaragoza, Vicente Aguadero, Indira Bhambi‐Blanco, Mònica Vidal‐Pla, Isabel Aparicio‐Calvente, M. Rosa Escoda‐Giralt, Joana Gallardo‐Campos, Joan Carles Ferreres, Luis Frisancho, Laia Mas‐Maresma, Patricia Aguilera‐Fernández, Sonia Marco‐Continente, Marina Sierra‐Boada, Pablo Andreu‐Cobo, Miquel Gallego, Francesca Canalias, Javier Hernando‐Redondo, Jaume Trapé   +17 more
wiley   +1 more source

Meropenem‐Induced Possible Mixed Drug‐Induced Liver Injury With Cholestatic Evolution: A Case Report Evaluated Using the Updated RUCAM (2016)

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Drug‐induced liver injury (DILI) remains a diagnosis of exclusion and requires systematic causality assessment. Meropenem is generally considered hepatically safe; however, rare cases of idiosyncratic DILI have been reported. We describe a 33‐year‐old female who developed progressive elevation of liver tests following exposure to meropenem ...
Nidal Mutawodeh, Sarah Saife, Akram Shalaby, Kamaleldein Einar, Motasem Kamal, Malik Hijaz, Tariq Hamadneh   +6 more
wiley   +1 more source

Methotrexate Toxicity in a Patient With Renal Failure Despite a Normal Methotrexate Concentration: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Methotrexate (MTX) is a folate antagonist widely used as a disease‐modifying antirheumatic drug (DMARD) in rheumatoid arthritis (RA), as well as in several malignancies and autoimmune disorders. Although low‐dose MTX (5–20 mg/week) is generally considered safe, it has a narrow therapeutic index, and toxicity can occur even at therapeutic doses,
Fatemeh Afra, Mahshad Ghoddusi, Mahsa Mottahedi, Maryam Albaji, Samira Kafan, Roya Saedpanah, Amir Shokri, Elham Nazar   +7 more
wiley   +1 more source

A Rare Presentation of Granulomatosis With Polyangiitis: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Granulomatosis with polyangiitis (GPA) is a rare ANCA‐associated necrotizing vasculitis that predominantly affects the respiratory tract and kidneys. Gastrointestinal involvement is uncommon, and pancreatic manifestations are exceedingly rare. Diffuse alveolar hemorrhage (DAH) represents a severe and potentially fatal complication. We report a
Anil Shahi, Ayush Neupane, Bishaka Adhikari   +2 more
wiley   +1 more source