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Cytokines in Thyroid Autoimmunity
The role of cytokines in the pathogenesis of autoimmune thyroid disease (ATD) has been extensively investigated over the past years. In patients with ATD, these molecules can be found in both the thyroid and sites of extrathyroidal complications of the disease.
R A, Ajjan, A P, Weetman
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Thyroiditis and human blood metabolites: A mendelian randomization study [PDF]
Background: The risk factors for thyroiditis, an inflammatory disease with a complex etiology, remain poorly understood. Blood metabolites are known to change during thyroiditis development, suggesting a close relationship between blood metabolites and ...
Shao Lijie +9 more
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Autoimmunity in thyroid disease
The autoimmune thyroid diseases, Graves' disease and autoimmune hypothyroidism, represent the two ends of a disease spectrum where an immune response is directed against the thyroid gland. In Graves' disease, antibodies directed against the thyrotropin receptor (TSH-R) lead to the development of glandular overactivity, while in autoimmune ...
Collins, J, Gough, S
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The Prevalence of Metabolic Syndrome in Patients with Euthyroid Autoimmune Thyroiditis
Objective: Autoimmune thyroid disease is one of the significant disorders of the thyroid gland and a common cause of primary hypothyroidism. Metabolic syndrome is an important metabolic disorder primarily associated with insulin resistance, diabetes ...
Ömer Arif Pamuk, Şakir Özgür Keşkek
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Autoimmune Thyroid Disorders [PDF]
Thyroid autoimmunity, as reflected by the presence in serum of autoantibodies directed against the thyroid autoantigens thyroglobulin (Tg) and thyroid peroxidase (TPO), is present in >10% of the US population over 12 years of age [1] and is the most common cause of endocrine dysfunction in iodine-sufficient populations [2].
Brown, Rosalind, Francis, Gary L.
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Hormonal and immunological characteristics of have been studied in individuals with initial autoimmune thyroiditis who have first- and second-degree relatives with autoimmune diseases.
L. A. Bolotskaya, A. A. Tarlyun
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Coexistence of Immune Checkpoint Inhibitor-Induced Autoimmune Diabetes and Pancreatitis
Autoimmune diabetes is a rare but severe endocrine toxicity induced by immune checkpoint inhibitor (ICI) treatment. It is unclear if ICI causes selective islet toxicity or non-selective pancreas toxicity.
Amy L. Zhang +4 more
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Fine needle aspiration cytology of thyroid and its correlation with serological findings
Background: Thyroid autoimmunity can cause several forms of thyroid disorders i.e. Grave’s disease, Hashimoto’s thyroiditis, atrophic autoimmune thyroiditis, post-partum thyroidits etc. Cytological diagnosis may be sometimes difficult is some cases.
S Karki, A Shrestha
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The IL-4 Level among Patients with Autoimmune Thyroiditis in Al-Najaf Governorate, Iraq
Background: The study of autoimmune thyroiditis is considered one of the challenges of sustainable development. Autoimmune thyroiditis includes largely cellular and humoral immune responses targeted at the thyroid gland, including Graves thyroiditis and ...
Sarah Hasan Kadhum Al-Huchaimi +2 more
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Studies concerning the antigenicity of thyroglobulin fragments allow the characterization of the epitopes but do not consider the role of heavier antigenic fragments that could result in vivo from the action of endoproteases.
L.H.B. Boechat, R.L. Zollner
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