Results 121 to 130 of about 397,447 (350)
Autoimmune Diabetes and Thyroiditis Complicating Treatment with Nivolumab
Programmed cell death-1 (PD-1) ligand inhibitors have gained popularity in the treatment of advanced non-small-cell lung cancer. The immune system is regulated by stimulatory and inhibitory signaling and aims to achieve the balance between activation and
Li Li +4 more
semanticscholar +1 more source
ABSTRACT Introduction Over 10 million thyroid function tests (TFTs) are carried out in England each year, most requests coming from primary care. Our previous work showed that only 25% of results for patients being treated with Levothyroxine fell within the TSH/FT4 boundary circumscribing 75% of untreated individuals.
Adrian H. Heald +8 more
wiley +1 more source
Potential targets for the hepatitis C virus-mediated autoimmune thyroiditis
Luís Jesuíno de Oliveira Andrade +2 more
openalex +2 more sources
A novel homozygous mutation of the AIRE gene in an APECED patient from Pakistan: case report and review of the literature [PDF]
Autoimmune-poly-endocrinopathy-candidiasis-ectodermal-dystrophy syndrome (APECED) is a rare monogenic recessive disorder caused by mutations in the autoimmune regulator (AIRE) gene.
Bellacchio, Emanuele +5 more
core +2 more sources
Vitamin D supplementation in patients with Hashimoto’s disease
Introduction : Hashimoto’s thyroiditis (HT) is the most common autoimmune disease and the leading cause of hypothyroidism in the world. The condition results in damage to the thyroid gland, brought about by the infiltration of lymphocytes.
Amelia Kasprzak +8 more
doaj +1 more source
Ipilimumab is a cytotoxic T-lymphocyte-associated protein 4 receptor antibody used for immunotherapy in cancer. Several immune-related adverse events are known.
David Carl +3 more
semanticscholar +1 more source
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley +1 more source
The term autoimmune thyroiditis encompasses a group of high prevalence thyroid disorders, which have been classified in different ways throughout the years. In this article some aspects related to its classification, epidemiology, susceptibility factors,
Melo, M
core

