Results 171 to 180 of about 29,121 (207)
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Chronic Autoimmune Thyroiditis

New England Journal of Medicine, 1996
In 1912, Hashimoto described four women in whom the thyroid gland was enlarged and appeared to have been transformed into lymphoid tissue (“struma lymphomatosa”).1 Although the patients were not initially hypothyroid, they became so after thyroid surgery.
C M, Dayan, G H, Daniels
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Thyroid Autoimmunity

2014
Autoimmune thyroid disease (AITD) is a multifactorial disease in which autoimmunity against thyroid antigens develops against a particular genetic background facilitated by exposure to environmental factors. Immunogenicity of the major thyroid antigens thyroid peroxidase, thyroglobulin (TG) and thyrotropin receptor (TSHR) is increased by genetic ...
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Autoimmune Thyroid Disease

Clinics in Laboratory Medicine, 1993
A considerable proportion of the thyroid diseases is due to aberrant immune reactions toward thyroid antigens. Autoreactivity is considered to be a normal process controlled by several suppressor mechanisms. Malfunction of these suppressor mechanisms may result in autoimmune disease.
P, Mooij, H A, Drexhage
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Development of thyroid autoimmunity

Acta Endocrinologica, 1985
Abstract. Two blood samples were taken at an interval of 5 years in a continuing epidemiological study of a rural population in south-western Finland with an age range of 40–64 years at commencement. Paired sera of 680 subjects were tested for antibodies against thyroglobulin and thyroid microsomal antigen. In the seroconversion cases the titres in the
K, Aho, A, Gordin, T, Palosuo, J, Takala
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Autoimmunity in Thyroid Disease

New England Journal of Medicine, 1959
AUTOIMMUNE processes have been implicated in a variety of systemic disorders, including some primary hemolytic anemias, idiopathic thrombocytopenia, drug-induced neutropenias and collagenvascular diseases. The immunologic basis for such disorders has not been directly substantiated, and some investigators resist the concept that the body can develop ...
M J, CLINE, H A, SELENKOW, M S, BROOKE
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CHRONIC THYROIDITIS AND AUTOIMMUNIZATION

Journal of the American Medical Association, 1957
• An explanation of chronic thyroiditis in man was sought in observations made on rabbits, dogs, guinea pigs, and human subjects. The rabbits received injections of saline extracts of rabbit thyroid glands. The tests for circulating autoantibodies utilized the phenomena of precipitation, complement fixation, and tanned-cell hemagglutination.
E, WITEBSKY   +4 more
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Autoimmune Thyroid Diseases

Seminars in Nuclear Medicine
Autoimmune thyroid diseases (AITDs) include a wide spectrum of thyroid diseases affecting more commonly women than men. The most frequent forms are Graves' Disease (GD) and Hashimoto's thyroiditis / Autoimmune Thyroiditis (AIT), but there are also other immunogenic destructive forms of thyroiditis, that is, silent and postpartum thyroiditis.
Petra Petranović Ovčariček   +2 more
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Thyroid autoimmunity and aging

Experimental Gerontology, 1998
Aging is associated with the appearance of several serum autoantibodies, including thyroid autoantibodies. The biological and clinical significance of this phenomenon is still unknown, because, with the exception of primary myxedema, the prevalence of clinically overt thyroid autoimmune diseases is not increased in the elderly.
MARIOTTI, STEFANO   +3 more
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Autoimmune thyroid diseases

Current Opinion in Rheumatology, 2007
Interesting clinical and basic studies have been published in the field of autoimmune thyroiditis (represented by Graves' disease and Hashimoto's thyroiditis) since January 2005. The review is organized into four main areas: genetics, environment, adaptive immune system, and innate immune system.The quest continues for the identification of ...
Patrizio, Caturegli   +3 more
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Autoimmune Thyroid Disease

Hospital Practice, 1984
Autoimmune mechanisms are responsible for only about 10% of all clinically apparent thyroid disorders. However, they play a major role in two of the three serious entities: Graves' disease and Hashimoto's thyroiditis. The complex questions that still persist with regard to the etiology and character of the autoimmune processes—and their clinical ...
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