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Autoimmune Thyroid Disease

Annual Review of Medicine, 1986
The concept of thyroid autoimmune disease now includes the following clinical entities: 1 degree thyrotoxicosis and goitrous thyroiditis (Hashimoto) with their variants, and 1 degree myxedema (atrophic thyroiditis); some cases of sporadic nontoxic goiters; most cases of neonatal hyperthyroidism; and a proportion of congenital athyreotic cretinism ...
G F Bottazzo, Deborah Doniach
openaire   +3 more sources

Autoimmunity in Thyroid Disease

New England Journal of Medicine, 1959
AUTOIMMUNE processes have been implicated in a variety of systemic disorders, including some primary hemolytic anemias, idiopathic thrombocytopenia, drug-induced neutropenias and collagenvascular diseases. The immunologic basis for such disorders has not been directly substantiated, and some investigators resist the concept that the body can develop ...
Martin J. Cline   +2 more
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Thyroid Autoimmunity

2014
Autoimmune thyroid disease (AITD) is a multifactorial disease in which autoimmunity against thyroid antigens develops against a particular genetic background facilitated by exposure to environmental factors. Immunogenicity of the major thyroid antigens thyroid peroxidase, thyroglobulin (TG) and thyrotropin receptor (TSHR) is increased by genetic ...
openaire   +2 more sources

Autoimmune thyroiditis and ROS

Autoimmunity Reviews, 2008
Autoimmune thyroiditis, also known as chronic lymphocytic or Hashimoto's thyroiditis, is characterized by infiltration of the thyroid gland by inflammatory cells and production of autoantibodies to thyroid-specific antigens thyroglobulin and thyroperoxidase.
Noel R. Rose, C. Lynne Burek
openaire   +3 more sources

Juvenile Autoimmune Thyroiditis

Journal of Pediatric Endocrinology and Metabolism, 2007
Autoimmune thyroiditis is a frequent cause of goiter in children and studies point to the increasing prevalence of juvenile autoimmune thyroiditis (JAT) in children and adolescents. Clinically, JAT can manifest, depending on the presence or absence of goiter, as either a goitrous form or atrophic form.
Raman K. Marwaha   +1 more
openaire   +3 more sources

Autoimmune Thyroid Disease

Clinics in Laboratory Medicine, 1993
A considerable proportion of the thyroid diseases is due to aberrant immune reactions toward thyroid antigens. Autoreactivity is considered to be a normal process controlled by several suppressor mechanisms. Malfunction of these suppressor mechanisms may result in autoimmune disease.
P. Mooij, H.A. Drexhage
openaire   +3 more sources

Stress and Thyroid Autoimmunity

Thyroid, 2004
While many studies have shown a connection between stress and autoimmune disease, most of the evidence for stress contributing to the onset and course of autoimmune disease is circumstantial and the mechanisms by which stress affects autoimmune disease are not fully understood.
Audrey W. Li   +3 more
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Development of thyroid autoimmunity

Acta Endocrinologica, 1985
Abstract. Two blood samples were taken at an interval of 5 years in a continuing epidemiological study of a rural population in south-western Finland with an age range of 40–64 years at commencement. Paired sera of 680 subjects were tested for antibodies against thyroglobulin and thyroid microsomal antigen. In the seroconversion cases the titres in the
J Takala, K Aho, A. Gordin, T. Palosuo
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CHRONIC THYROIDITIS AND AUTOIMMUNIZATION

Journal of the American Medical Association, 1957
• An explanation of chronic thyroiditis in man was sought in observations made on rabbits, dogs, guinea pigs, and human subjects. The rabbits received injections of saline extracts of rabbit thyroid glands. The tests for circulating autoantibodies utilized the phenomena of precipitation, complement fixation, and tanned-cell hemagglutination.
Noel R. Rose   +4 more
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Autoimmune thyroid diseases

Current Opinion in Rheumatology, 2007
Interesting clinical and basic studies have been published in the field of autoimmune thyroiditis (represented by Graves' disease and Hashimoto's thyroiditis) since January 2005. The review is organized into four main areas: genetics, environment, adaptive immune system, and innate immune system.The quest continues for the identification of ...
Hiroaki Kimura   +3 more
openaire   +2 more sources

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