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La Presse Médicale, 2012
This review of human autoimmune thyroid disease (AITD) focuses mainly on the epidemiology and pathophysiology of this very common disorder, although some specific clinical situations are discussed. One peculiarity of AITD is the existence of two contrasting phenotypes: hypothyroid thyroiditis and hyperthyroid Graves' disease.
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This review of human autoimmune thyroid disease (AITD) focuses mainly on the epidemiology and pathophysiology of this very common disorder, although some specific clinical situations are discussed. One peculiarity of AITD is the existence of two contrasting phenotypes: hypothyroid thyroiditis and hyperthyroid Graves' disease.
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Annual Review of Medicine, 1986
The concept of thyroid autoimmune disease now includes the following clinical entities: 1 degree thyrotoxicosis and goitrous thyroiditis (Hashimoto) with their variants, and 1 degree myxedema (atrophic thyroiditis); some cases of sporadic nontoxic goiters; most cases of neonatal hyperthyroidism; and a proportion of congenital athyreotic cretinism ...
G F, Bottazzo, D, Doniach
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The concept of thyroid autoimmune disease now includes the following clinical entities: 1 degree thyrotoxicosis and goitrous thyroiditis (Hashimoto) with their variants, and 1 degree myxedema (atrophic thyroiditis); some cases of sporadic nontoxic goiters; most cases of neonatal hyperthyroidism; and a proportion of congenital athyreotic cretinism ...
G F, Bottazzo, D, Doniach
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Current Opinion in Rheumatology, 2007
Interesting clinical and basic studies have been published in the field of autoimmune thyroiditis (represented by Graves' disease and Hashimoto's thyroiditis) since January 2005. The review is organized into four main areas: genetics, environment, adaptive immune system, and innate immune system.The quest continues for the identification of ...
Patrizio, Caturegli +3 more
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Interesting clinical and basic studies have been published in the field of autoimmune thyroiditis (represented by Graves' disease and Hashimoto's thyroiditis) since January 2005. The review is organized into four main areas: genetics, environment, adaptive immune system, and innate immune system.The quest continues for the identification of ...
Patrizio, Caturegli +3 more
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The catalytic role of iodine excess in loss of homeostasis in autoimmune thyroiditis
Current Opinion in Endocrinology, Diabetes & Obesity, 2018Purpose of review To review the latest developments concerning the role of iodine in the pathophysiology of autoimmune thyroiditis. Recent findings Recent studies have provided evidence that in areas with excess iodine intake, increased incidence of ...
L. Duntas
semanticscholar +1 more source
2014
Autoimmune thyroid disease (AITD) is a multifactorial disease in which autoimmunity against thyroid antigens develops against a particular genetic background facilitated by exposure to environmental factors. Immunogenicity of the major thyroid antigens thyroid peroxidase, thyroglobulin (TG) and thyrotropin receptor (TSHR) is increased by genetic ...
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Autoimmune thyroid disease (AITD) is a multifactorial disease in which autoimmunity against thyroid antigens develops against a particular genetic background facilitated by exposure to environmental factors. Immunogenicity of the major thyroid antigens thyroid peroxidase, thyroglobulin (TG) and thyrotropin receptor (TSHR) is increased by genetic ...
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Thyroid Autoimmunity and Ageing
Hormone Research, 1995Ageing is associated with the appearance of several serum autoantibodies, including thyroid autoantibodies. The biological and clinical significance of this phenomenon is still unknown, since, with the exception of primary myxedema, the prevalence of clinically overt thyroid autoimmune diseases is not increased in the elderly. The peculiar link between
PINCHERA A +7 more
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Hospital Practice, 1984
Autoimmune mechanisms are responsible for only about 10% of all clinically apparent thyroid disorders. However, they play a major role in two of the three serious entities: Graves' disease and Hashimoto's thyroiditis. The complex questions that still persist with regard to the etiology and character of the autoimmune processes—and their clinical ...
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Autoimmune mechanisms are responsible for only about 10% of all clinically apparent thyroid disorders. However, they play a major role in two of the three serious entities: Graves' disease and Hashimoto's thyroiditis. The complex questions that still persist with regard to the etiology and character of the autoimmune processes—and their clinical ...
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Thyroid Autoimmunity and Environment
Hormone and Metabolic Research, 2009Autoimmune thyroid disorders (AITDs) are the result of a complex interplay between genetic and environmental factors, the former account for about 70-80% of liability to develop AITDs. However, at least 20-30% is contributed by environmental factors, which include certainly smoking (at least for Graves' disease and orbitopathy), probably stress, iodine
TANDA, MARIA LAURA PIERA +7 more
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Urticaria and Thyroid Autoimmunity
Thyroid, 2011Chronic urticaria is a common clinical condition whose etiology, in about 75% of cases, is unknown and is therefore called chronic idiopathic urticaria (CIU). A link between CIU and autoimmune thyroid diseases was proposed several decades ago. Here we review this topic.Several studies have been performed to determine if and to what degree there is an ...
M. Bagnasco +5 more
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Seminars in Nuclear Medicine
Autoimmune thyroid diseases (AITDs) include a wide spectrum of thyroid diseases affecting more commonly women than men. The most frequent forms are Graves' Disease (GD) and Hashimoto's thyroiditis / Autoimmune Thyroiditis (AIT), but there are also other immunogenic destructive forms of thyroiditis, that is, silent and postpartum thyroiditis.
Petra Petranović Ovčariček +2 more
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Autoimmune thyroid diseases (AITDs) include a wide spectrum of thyroid diseases affecting more commonly women than men. The most frequent forms are Graves' Disease (GD) and Hashimoto's thyroiditis / Autoimmune Thyroiditis (AIT), but there are also other immunogenic destructive forms of thyroiditis, that is, silent and postpartum thyroiditis.
Petra Petranović Ovčariček +2 more
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