Results 61 to 70 of about 27,824 (249)

Rotavirus vaccination is not associated with incident celiac disease or autoimmune thyroid disease in a national cohort of privately insured children

Scientific Reports, 2022
Rotavirus infection is a potential trigger for autoimmune diseases, and previous reports note associations between rotavirus vaccination and type 1 diabetes. In this report, we examine the association between rotavirus vaccination and autoimmune diseases
Catherine Kim, Zhe Yin, Neil Kamdar, Grace J. Lee   +3 more
doaj   +1 more source

Estimation the Maximum Tolerance Activity of Blood by a Simple Algorithm Method in Pediatric Differentiated Thyroid Cancer Patients Treated With Empirical Radioactive Iodine Dosing Based on Risk Stratification

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT After total thyroidectomy for pediatric differentiated thyroid cancer (DTC), the subsequent radioactive iodine (RAI) treatment is a robust therapy, the dosing of which is a major concern. This study was designed to evaluate the “as high as safe administration” (AHASA) principle of RAI treatment in pediatric DTC patients based on the maximum ...
Yu‐Wen Chen, Cheng‐Hsun Chuang, Che‐Wei Wu, Feng‐Yu Chiang, Hon‐Man Chen, Kun‐Der Lin, Chih‐Hung Lin, Yung‐Chang Lai, Tzu‐Yen Huang   +8 more
wiley   +1 more source

Cytokines in Thyroid Autoimmunity

Autoimmunity, 2003
The role of cytokines in the pathogenesis of autoimmune thyroid disease (ATD) has been extensively investigated over the past years. In patients with ATD, these molecules can be found in both the thyroid and sites of extrathyroidal complications of the disease.
R A Ajjan, Anthony P. Weetman
openaire   +2 more sources

Systematic Multi‐Trait Study of Genetic Correlation and Causality Relationships Between General Medical Conditions and Mental Disorders

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Increasing evidence has highlighted bidirectional associations between mental disorders and general medical conditions, with underlying causes ranging from lifestyle habits and side effects from medications to genetic contributions. Novel methods now provide a way to estimate the shared genetic underpinnings and the possibility of
Ron Nudel, Maria Da Re, Michael E. Benros   +2 more
wiley   +1 more source

Thyroid hormonal disturbances related to treatment of hepatitis C with interferon-alpha and ribavirin

Clinics, 2011
OBJECTIVE: To characterize thyroid disturbances induced by interferon-alpha and ribavirin therapy in patients with chronic hepatitis C. INTRODUCTION: Interferon-alpha is used to treat chronic hepatitis C infections.
Debora Lucia Seguro Danilovic, Maria Cassia Mendes-Correa, Maria Cristina Chammas, Heverton Zambrini, Suemi Marui   +4 more
doaj   +1 more source

The Aetiology of Elevated Total Serum Immunoglobulin E in Children

Acta Paediatrica, EarlyView.
ABSTRACT Aim The paucity of real‐world data on the aetiology of elevated total serum immunoglobulin E (TS‐IgE) in children afflicts families and health care systems with diagnostic uncertainty. We explored a cohort of children with TS‐IgE levels over 1000 kU/L, focusing on the prevalence of atopic and non‐atopic conditions, the aetiology of extremely ...
Aliisa Ärölä, Kaarina Kukkonen, Svetlana Vakkilainen   +2 more
wiley   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Autoimmune Thyroiditis in Childhood

Journal of Clinical Research in Pediatric Endocrinology, 2012
Autoimmune thyroiditis (AIT) is the most common thyroid disorder in the pediatric age range. The disease results from an as yet poorly characterized defect or defects in immunoregulation and a cascade of events progressing from lymphocyte infiltration of the thyroid, to T-cell- and cytokine-mediated thyroid follicular cell injury, and apoptotic cell ...
openaire   +3 more sources

Genetic Profiling Reveals the Distinctions Among MTX‐Associated DLBCL, EBV‐Positive Mucocutaneous Ulcer, and EBV + DLBCL

Cancer Science, EarlyView.
EBV‐ MTX‐DLBCL shows higher driver gene mutation rates and worse outcomes after MTX discontinuation compared to EBV+ MTX‐DLBCL. IDD‐LPDs have lower mutation rates in genes related to clonal hematopoiesis (TET2/DNMT3A) and immune evasion (CD58) compared to EBV + DLBCL. ABSTRACT The WHO recently changed the outline of immunodeficiency/dysregulation (IDD)‐
Takumi Takahashi, Keisuke Sawada, Takahisa Yamashita, Wataru Yamamoto, Yosuke Iijima, Akiko Adachi, Makoto Kashimura, Takayuki Tabayashi, Masahiro Kizaki, Takahiro Kaneko, Jun‐ichi Tamaru, Morihiro Higashi, Shuji Momose   +12 more
wiley   +1 more source

Selenium and thyroid autoimmunity

Biologics: Targets & Therapy, 2008
The trace element selenium (Se) occurs in the form of the amino acid selenocysteine in selenoproteins. Selenoproteins exerts multiple physiological effects in human health, many of which are related with regulation of reduction-oxidation processes.
openaire   +4 more sources