Results 61 to 70 of about 393,919 (333)

Cytokines in Thyroid Autoimmunity

open access: yesAutoimmunity, 2003
The role of cytokines in the pathogenesis of autoimmune thyroid disease (ATD) has been extensively investigated over the past years. In patients with ATD, these molecules can be found in both the thyroid and sites of extrathyroidal complications of the disease.
R A, Ajjan, A P, Weetman
openaire   +2 more sources

Fine needle aspiration cytology of thyroid and its correlation with serological findings

open access: yesJournal of Pathology of Nepal, 2017
Background: Thyroid autoimmunity can cause several forms of thyroid disorders i.e. Grave’s disease, Hashimoto’s thyroiditis, atrophic autoimmune thyroiditis, post-partum thyroidits etc. Cytological diagnosis may be sometimes difficult is some cases.
S Karki, A Shrestha
doaj   +1 more source

Autoimmunity in thyroid disease

open access: yesEuropean Journal of Nuclear Medicine and Molecular Imaging, 2002
The autoimmune thyroid diseases, Graves' disease and autoimmune hypothyroidism, represent the two ends of a disease spectrum where an immune response is directed against the thyroid gland. In Graves' disease, antibodies directed against the thyrotropin receptor (TSH-R) lead to the development of glandular overactivity, while in autoimmune ...
Collins, J, Gough, S
openaire   +2 more sources

Reactivity of anti-thyroid antibodies to thyroglobulin tryptic fragments: comparison of autoimmune and non-autoimmune thyroid diseases

open access: yesBrazilian Journal of Medical and Biological Research, 1999
Studies concerning the antigenicity of thyroglobulin fragments allow the characterization of the epitopes but do not consider the role of heavier antigenic fragments that could result in vivo from the action of endoproteases.
L.H.B. Boechat, R.L. Zollner
doaj   +1 more source

Treatment with Myo-Inositol and Selenium Ensures Euthyroidism in Patients with Autoimmune Thyroiditis

open access: yesInternational Journal of Endocrinology, 2017
Clinical evidences have highlighted the efficacy of myo-inositol and selenium in the treatment of autoimmune thyroiditis. Aim of this study was to further analyze the role of myo-inositol plus selenium (Myo-Ins-Se) in restoring a normal thyroid function ...
M. Nordio, S. Basciani
semanticscholar   +1 more source

An Out‐of‐Place Etiology: Recognizing FMR1 Premutation in the Memory Clinic

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The FMR1 gene premutation (55–200 CGG repeats) is usually associated with a wide range of symptoms and phenotypes within the Fragile X‐tremor/ataxia syndrome (FXTAS), but may also manifest as predominant or isolated cognitive decline. We describe three male patients referred for progressive cognitive impairment and behavioral changes. Standard
Guido Greco   +7 more
wiley   +1 more source

Chemokines in thyroid autoimmunity

open access: yesBest Practice & Research Clinical Endocrinology & Metabolism, 2023
The chemokine receptor CXCR3 and its chemokines CXCL9, CXCL10, and CXCL11 are involved in the pathogenesis of autoimmune diseases. Th1 lymphocytes are recruited by Th1 chemokines, secreted by damaged cells. In inflamed tissues, the attracted Th1 lymphocytes induce the IFN-gamma and TNF-alpha release, that stimulates the secretion of Th1 chemokines ...
Ferrari, Silvia Martina   +11 more
openaire   +3 more sources

Thyroid Autoimmunity as a Window to Autoimmunity: An Explanation for Sex Differences in the Prevalence of Thyroid Autoimmunity [PDF]

open access: yes, 2015
Autoimmune thyroid diseases (AITDs), predominately Graves׳ disease and Hashimoto׳s thyroiditis, comprise the most common autoimmune diseases in humans.
Merrill, Stephen, Mu, Ying
core   +1 more source

Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease

open access: yesAdvanced Science, EarlyView.
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou   +18 more
wiley   +1 more source

Psoriasis and Hashimoto's thyroiditis in a child with down syndrome

open access: yesIndian Journal of Paediatric Dermatology, 2016
Down syndrome (DS), or trisomy 21, is the most common chromosomal disorder. DS has been associated with autoimmune diseases including autoimmune thyroiditis, Type 1 diabetes mellitus, celiac disease, autoimmune chronic active hepatitis, alopecia ...
Hilal Gokalp, Ayse Deniz Akkaya
doaj   +1 more source

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