Results 121 to 130 of about 436,604 (311)

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Alemtuzumab-induced remission of multiple sclerosis-associated uveitis [PDF]

, 2016
Purpose The purpose of the study was to report a case of multiple sclerosis (MS)-associated uveitis refractory to conventional immunosuppressants, with subsequent remission following treatment with alemtuzumab.
Carreño, Ester, Dick, Andrew D., Lee, Richard W. J., Pickersgill, Trevor, Robertson, Neil, Willis, Mark   +5 more
core   +4 more sources

Severity of Experimental Autoimmune Uveitis Is Reduced by Pretreatment with Live Probiotic Escherichia coli Nissle 1917

Cells, 2020
Non-infectious uveitis is considered an autoimmune disease responsible for a significant burden of blindness in developed countries and recent studies have linked its pathogenesis to dysregulation of the gut microbiota.
O. Dušek, Alena Fajstová, A. Klimova, P. Svozilkova, T. Hrncír, M. Kverka, Š. Coufal, Johan Šlemín, H. Tlaskalova-Hogenova, J. Forrester, J. Heissigerova   +10 more
semanticscholar   +1 more source

HHV‐8/KSHV in Solid Organ Transplantation: Current Gaps of Knowledge and Future Directions

Transplant Infectious Disease, EarlyView.
Risk mitigation strategies, including donors/recipients screening, DNAemia monitoring in recipients at risk, CNI‐to‐mTOR inhibitors switch, antivirals, and rituximab for KICS, may mitigate the impact of HHV‐8/KSHV infection in SOT. This review provides an update on KICS, identifies research gaps, and summarizes advances in screening and management ...
Alessandra Mularoni, Andrea Cona, Malgorzata Mikulska, Francesca Pecoraro, Carlotta Piazza, Elda De Vita, Giada Pietrosi, Matteo Bulati, Tiziana Lazzarotto, Mario Luppi   +9 more
wiley   +1 more source

P2Y2R Deficiency Attenuates Experimental Autoimmune Uveitis Development

PLOS ONE, 2015
We aimed to study the role of the nucleotide receptor P2Y2R in the development of experimental autoimmune uveitis (EAU). EAU was induced in P2Y2+/+ and P2Y2-/- mice by immunization with IRBP peptide or by adoptive transfer of in vitro restimulated semi-purified IRBP-specific enriched T lymphocytes from spleens and lymph nodes isolated from native C57Bl/
Judice De Menezes Relva, Lia, Makhoul, Maya, Dewispelaere, Remi, Caspers, Laure, Communi, Didier, Boeynaems, Jean-Marie, Robaye, Bernard, Bruyns, Catherine, Willermain, Francois   +8 more
openaire   +4 more sources

Role of Psychological Stress in Noninfectious Uveitis

Current Medical Issues
Background: Psychological stress has been shown to be associated with the etiopathogenesis of several autoimmune diseases. Uveitis can be a sight-threatening disease if not treated promptly and adequately.
Shikha Benson, Arun Rachana, Deepa Jose, Smitha Jasper, Roselin Charles, Sheeja Susan John   +5 more
doaj   +1 more source

Comparative analysis of induced vs. spontaneous models of autoimmune uveitis targeting the interphotoreceptor retinoid binding protein.

PLoS ONE, 2013
Animal models of autoimmunity to the retina mimic specific features of human uveitis, but no model by itself reproduces the full spectrum of human disease.
Jun Chen, Haohua Qian, Reiko Horai, Chi-Chao Chan, Yishay Falick, Rachel R Caspi   +5 more
doaj   +1 more source

A Review of Ankylosing Spondylitis [PDF]

, 2017
Ankylosing spondylitis (AS) is a systemic autoimmune disorder that induces ankylosis of the spine (fusion of the vertebrae at their various joints) and inflammatory arthritis of peripheral joints among other symptoms.
Owen, Hannah L
core   +1 more source

Characterization of clinical and immune responses in an experimental chronic autoimmune uveitis model.

American Journal of Pathology, 2020
Autoimmune uveitis is a sight-threatening intraocular inflammatory disease. For over thirty years, the mouse model of experimental autoimmune uveitis (EAU) has been employed to investigate disease mechanisms and test immunotherapeutic approaches. However,
Nai‐Wen Fan, Joy Li, S. Mittal, W. Foulsham, Elsayed Elbasiony, Rachel M. Huckfeldt, S. Chauhan, Yihe Chen   +7 more
semanticscholar   +1 more source

A Case Study and Review of the Literature on IgA Nephropathy in Crohn's Disease

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT IgA nephropathy (IgAN) is the most frequently reported glomerular disease associated with inflammatory bowel disease (IBD), particularly Crohn's disease (CD), although pediatric cases remain rare. We report IgAN in a 16‐year‐old male with CD following intestinal surgery and during long‐term infliximab therapy, with renal impairment occurring ...
Giovanna Fernanda Vazzana, Alessia Romano, Chiara Casuscelli, Alberto La Spada, Domenico Santoro, Roberto Chimenz, Claudio Romano   +6 more
wiley   +1 more source