Results 21 to 30 of about 28,173 (225)

Retinal glycoprotein enrichment by concanavalin a enabled identification of novel membrane autoantigen synaptotagmin-1 in equine recurrent uveitis. [PDF]

, 2012
Complete knowledge of autoantigen spectra is crucial for understanding pathomechanisms of autoimmune diseases like equine recurrent uveitis (ERU), a spontaneous model for human autoimmune uveitis. While several ERU autoantigens were identified previously,
A Lux, AK Berntson, AK Steck, B Wiggert, Barbara Amann, BD McNeil, BM Spiess, C Eberhardt, C Kiel, CA Deeg, CA Deeg, CA Deeg, CA Deeg, CA Deeg, CA Deeg, CA Deeg, CA Deeg, CM Kalsow, Cornelia A. Deeg, CW Morgans, D Josic, D Schubert, ER Chapman, G Glavan, H de Wit, Hassan Y. Naim, HY Naim, J Petersen, J Ratelade, JK Zipplies, JP Collin, JW Becker, K Marino, KF Greif, KS Shamsi, LN Troelsen, Lucienne Chatenoud, M Mirshahi, M Takamori, M Takamori, M Takamori, M Takamori, M Vrljic, M Zhao, MA Koontz, Margarete E. Swadzba, MC Ehrenhofer, MC Kwok, MC Papadopoulos, ME Swadzba, MJ Lewis, N Martin-Moutot, P Ariel, P David, P Redecker, RA Levy, RL Degroote, RR Caspi, S Bohm, SM Hauck, SM Hauck, Stefanie M. Hauck, V Gauba, VA Lennon, VA Lennon, W Han, W Vennekate, XQ Liu, Y Wang   +68 more
core   +6 more sources

Integrated Transcriptome Analysis of Iris Tissues in Experimental Autoimmune Uveitis

Frontiers in Genetics, 2022
Uveitis is a severe ocular inflammatory disease that affects the uvea and frequently results in visual impairment, even irreversible blindness. The current treatments for uveitis have exhibited adverse side effects. To find novel targets of this disease,
Dan Li, Dan Li, Dan Li, Dan Li, Chang Huang, Chang Huang, Chang Huang, Chang Huang, Xiaoyan Han, Xiaoyan Han, Xiaoyan Han, Xiaoyan Han, Jianguo Sun, Jianguo Sun, Jianguo Sun, Jianguo Sun   +15 more
doaj   +1 more source

Atopobiosis and Dysbiosis in Ocular Diseases: Is Fecal Microbiota Transplant and Probiotics a Promising Solution?

Journal of Ophthalmic & Vision Research, 2021
Purpose: To highlight the role of atopobiosis and dysbiosis in the pathomechanism of autoimmune uveitis, therefore supporting fecal microbiota transplant (FMT) and probiotics as potential targeted-treatment for uveitis.
Triana Hardianti Gunardi, Diannisa Paramita Susantono, Andi Arus Victor, Ratna Sitompul   +3 more
doaj   +1 more source

MicroRNAs in the regulation of Th17/Treg homeostasis and their potential role in uveitis

Frontiers in Genetics, 2022
Th17 and regulatory T cells (Tregs) play crucial roles in the pathogenesis of autoimmune diseases. Th17/Treg homeostasis is critically involved in maintaining the immune balance.
Fen Tang, Zhou Zhou, Kongqian Huang, Wen Deng, Jiali Lin, Ruoyun Chen, Min Li, Fan Xu   +7 more
doaj   +1 more source

Describing the Clinical and Laboratory Features and HLA-B Pattern of Adult-Onset Idiopathic Autoimmune Uveitis at a Tertiary Hospital in South India: A Cross-Sectional Study

The Scientific World Journal, 2022
Introduction. There is a scarcity of information available on clinical and laboratory features of adult-onset idiopathic autoimmune uveitis. Therefore, we conducted a single centre descriptive cross-sectional study. Patients and Methods.
Jyothi Visalakshy, Sandeep Surendran, Salil Ganu, Kannisha Shah, C. B. Mithun, Vishal Marwaha, Lalitha Biswas, Niveditha Kartha, Gopal Pillai   +8 more
doaj   +1 more source

Overexpressing Kallistatin Aggravates Experimental Autoimmune Uveitis Through Promoting Th17 Differentiation

Frontiers in Immunology, 2021
Kallistatin or kallikrein-binding protein (KBP) has been reported to regulate angiogenesis, inflammation and tumor progression. Autoimmune uveitis is a common, sight-threatening inflammatory intraocular disease.
Nu Chen, Shuang Chen, Zhihui Zhang, Xuexue Cui, Lingzi Wu, Kailei Guo, Hui Shao, Jian-Xing Ma, Xiaomin Zhang   +8 more
doaj   +1 more source

The associations between interleukin 10 polymorphisms and susceptibility to autoimmune uveitis – a meta-analysis

Central European Journal of Immunology, 2019
Autoimmune uveitis is an ocular inflammatory disease that is associated with genetic factors. Interleukin 10 (IL-10) is an immune-regulatory cytokine of autoimmune diseases. IL-10 is considered a candidate gene for uveitis. We evaluate the association of
Jae Jung, Gwan Song, Jae-Hoon Kim, Sung Choi   +3 more
doaj   +1 more source

Equine recurrent uveitis - A spontaneous horse model of uveitis [PDF]

, 2008
Equine recurrent uveitis (ERU) is an autoimmune disease that occurs with a high prevalence (10%) in horses. ERU represents the only reliable spontaneous model for human autoimmune uveitis.
Altmann, Frank, Amann, Barbara, Deeg, Cornelia A., Hauck, Stefanie M., Pompetzki, Dirk, Raith, Albert, Schmalzl, Thomas, Stangassinger, Manfred, Ueffing, Marius   +8 more
core   +1 more source

Type I Interferon Therapy Limits CNS Autoimmunity by Inhibiting CXCR3-Mediated Trafficking of Pathogenic Effector T Cells

Cell Reports, 2019
Summary: Type I interferons (IFNs) have therapeutic potential in CNS autoimmune diseases, such as uveitis, but the molecular mechanisms remain unclear.
Weiwei Wang, Wai Po Chong, Chunmei Li, Zilin Chen, Sihan Wu, Hongyan Zhou, Ying Wan, Wanjun Chen, Igal Gery, Yizhi Liu, Rachel R. Caspi, Jun Chen   +11 more
doaj   +1 more source

PATTERN OF ANTERIOR UVEITIS IN KMN EYECARE

IJRETINA (International Journal of Retina), 2023
Introduction: Anterior uveitis is the most common form of uveitis, but there are relatively few anterior uveitis studies in Indonesia. The purpose of this study is to analyze the pattern of anterior uveitis in KMN EyeCare.
Kevin Kevin, Rifna Lutfiamida
doaj   +1 more source