Results 31 to 40 of about 199,640 (297)

Juvenile polyautoimmunity in a rheumatology setting [PDF]

open access: yes, 2019
Q1Q1Paciente jovenOvert polyautoimmunity (PolyA) corresponds to the presence of more than one well-defined autoimmune disease (AD) manifested clinically in a single patient.
Mosquera, Catalina   +14 more
core   +1 more source

Targets of Neutrophil Influx and Weaponry: Therapeutic Opportunities for Chronic Obstructive Airway Disease

open access: yesJournal of Immunology Research, 2017
Neutrophils are important effector cells of antimicrobial immunity in an acute inflammatory response, with a primary role in the clearance of extracellular pathogens.
Carina Kärrman Mårdh   +6 more
doaj   +1 more source

Environmental factors associated with juvenile idiopathic inflammatory myopathy clinical and serologic phenotypes

open access: yesPediatric Rheumatology Online Journal, 2022
Background Environmental exposures have been associated with the juvenile idiopathic inflammatory myopathies (JIIM). We undertook a questionnaire-based study to evaluate patient-reported exposures as possible risk factors for JIIM.
Jonathan C. Scalabrini   +8 more
doaj   +1 more source

REGULATORY ROLE OF OX22HIGH T-CELLS IN MERCURY-INDUCED AUTOIMMUNITY IN THE BROWN NORWAY RAT [PDF]

open access: yes, 1993
The monoclonal antibody OX22 defines a functional split within CD4+ T cells in the rat, with OX22high cells mainly producing interleukin 2 (IL-2) and interferon γ and responsible for delayed-type hypersensitivity responses, and OX22low cells mainly ...
P W Mathieson   +6 more
core   +1 more source

PBMC fixation and processing for Chromium single-cell RNA sequencing

open access: yesJournal of Translational Medicine, 2018
Background Interest in single-cell transcriptomic analysis is growing rapidly, especially for profiling rare or heterogeneous populations of cells. In almost all reported works investigators have used live cells, which introduces cell stress during ...
Jinguo Chen   +5 more
doaj   +1 more source

The Autoimmune Ecology [PDF]

open access: yesFrontiers in Immunology, 2016
Las enfermedades autoinmunes (EA) representan un grupo heterogéneo de trastornos que afectan a órganos diana específicos o a múltiples sistemas de órganos. Estas afecciones comparten mecanismos inmunopatógenos comunes (es decir, la tautología autoinmune), que explican las similitudes clínicas que tienen entre ellas, así como su agrupación familiar (es ...
Juan‐Manuel Anaya   +4 more
openaire   +4 more sources

International Conference “Autoimmune Diseases: Main Problems and Solutions” (November 9–10, 2023 Riga). Abstract Book [PDF]

open access: yes, 2023
VirA project Homepage: https://vira-twinning.eu/Conference is organized by the Rīga Stradiņš University within the frame of the EC Horizon 2020 Framework program project “Reducing networking gaps between Rīga Stradiņš University (RSU) and internationally-

core   +1 more source

Clinical Factors Associated with Time-Specific Distribution of 18F-Fluorodeoxyglucose in Large-Vessel Vasculitis

open access: yesScientific Reports, 2019
18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) can detect vascular inflammation in large-vessel vasculitis (LVV). Clinical factors that influence distribution of FDG into the arterial wall and other tissues have not been characterized in
Joel S. Rosenblum   +5 more
doaj   +1 more source

Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium

open access: yesRespiratory Research, 2017
Background Smoking and aberrant epithelial responses are risk factors for lung cancer as well as chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis.
Lynne A. Murray   +9 more
doaj   +1 more source

Interaction between extracellular matrix molecules and microbial pathogens: evidence for the missing link in autoimmunity with rheumatoid arthritis as a disease model. [PDF]

open access: yes, 2014
Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation followed by tissue rebuilding or fibrosis. A failure by the body to regulate inflammation effectively is one of the hallmarks of RA.
Saralili Dipa Robertson   +14 more
core   +1 more source

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