Results 11 to 20 of about 4,410 (179)

Pharmacokinetics of adrenaline autoinjectors [PDF]

Clinical & Experimental Allergy, 2021
AbstractAnaphylaxis is a medical emergency with adrenaline acknowledged as the first‐line therapy. It is therefore important that patients have access to self‐injectable adrenaline in the community. Manufacturers have been requested by European Medicine Regulators to generate pharmacokinetic data for these autoinjector devices.
Paul J. Turner, Antonella Muraro, Graham Roberts   +2 more
openaire   +5 more sources

The pharmacokinetics of epinephrine/adrenaline autoinjectors [PDF]

Allergy, Asthma & Clinical Immunology, 2021
AbstractBackgroundFor a century, epinephrine has been the drug of choice for acute treatment of systemic allergic reactions/anaphylaxis. For 40 years, autoinjectors have been used for the treatment of anaphylaxis. Over the last 20 years, intramuscular epinephrine injected into the thigh has been recommended for optimal effect.ObjectiveTo review the ...
Sten Dreborg, Harold Kim
openaire   +4 more sources

Pharmacoeconomic analysis of using benralizumab for treatment of severe asthma in inpatient and outpatient settings

Фармакоэкономика, 2022
Objective: evaluation of the pharmacoeconomic feasibility of using benralizumab in the form of autoinjector (pen-injector device) in outpatient facilities compared with its use in the form of a syringe in hospital settings for the treatment of severe ...
M. V. Zhuravleva, S. N. Avdeev, Yu. V. Gagarina, T. V. Marin   +3 more
doaj   +1 more source

Quantification of atropine sulphate monohydrate and obidoxime dichloride in two‐chamber autoinjectors for accessing uniformity of dosage

Analytical Science Advances, 2022
In the treatment of organophosphate poisoning atropine sulphate monohydrate (AT) and obidoxime dichloride (OB) play a vital role. Currently, the Austrian Armed Forces use the DOUBLEPEN OA two‐chamber autoinjector (ChemProtect) to administer these two ...
Iva Spreitzer, Paniz Morawej, Richard Wosolsobe, Rainer Stinzl, Judith Wackerlig   +4 more
doaj   +1 more source

Predictors of Adherence Among Patients With Multiple Sclerosis Using the BETACONNECT® Autoinjector: A Prospective Observational Cohort Study

Frontiers in Neurology, 2021
Background: In patients with multiple sclerosis (MS), non-adherence to disease-modifying drug therapy is associated with an increased rate of MS relapses.
Wolfgang Köhler, Kirsten Bayer-Gersmann, Thomas Neußer, Markus Schürks, Tjalf Ziemssen   +4 more
doaj   +1 more source

Autoinjectors Preferred for Intramuscular Epinephrine in Anaphylaxis and Allergic Reactions

Western Journal of Emergency Medicine, 2016
Introduction: Epinephrine is the treatment of choice for anaphylaxis. We surveyed emergency department (ED) health care providers regarding 2 methods of intramuscular (IM) epinephrine administration (autoinjector and manual injection) for the ...
Ronna L Campbell, M. Fernanda Bellolio, Megan S. Motosue, Kharmene L. Sunga, Christine M. Lohse, Maria I. Rudis   +5 more
doaj   +1 more source

Novel cannula design improves large volume auto-injection rates for high viscosity solutions

Drug Delivery, 2022
A prototype reusable large-volume (2 mL) autoinjector (LVAI) was designed to compare injection performance of a novel 27 gauge ultra-thin wall (UTW) pre-filled syringe (PFS) cannula (8 mm external cannula length, 14.4 mm total needle length) against an ...
Bruce C. Roberts, Christopher Rini, Rick Klug, Douglas B. Sherman, Didier Morel, Ronald J. Pettis   +5 more
doaj   +1 more source

Patients’ Perceptions and Preferences Regarding Two Different Forms of Methotrexate Autoinjectors for Moderate to Severe Rheumatoid Arthritis: A European Crossover Survey

Patient Preference and Adherence, 2020
Jean-David Zeitoun,1 Yves Morvan2 1Département de Gastroentérologie et Nutrition, Hôpital Saint-Antoine, Assistance Publique Hôpitaux de Paris, Paris 75012, France; 2IPSOS Healthcare Department, Paris 75013, FranceCorrespondence:
Zeitoun JD, Morvan Y
doaj  

Increasing cost of epinephrine autoinjectors

Journal of Allergy and Clinical Immunology, 2012
2016-03-19T19:12 ...
Emma, Westermann-Clark, Westermann-Clark, Emma, Fitzhugh, David J., Lockey, Richard F.   +3 more
openaire   +3 more sources

Optimal Choice of Acetylcholinesterase Reactivators for Antidoral Treatment of Nerve Agent Intoxication

Acta Medica, 2010
The studies dealing with mechanism of organophosphates (OP)/nerve agent action, prophylaxis and treatment of intoxications is a very hot topic at present.
Jiří Bajgar
doaj   +1 more source