Results 21 to 30 of about 589 (161)
Cathelicidin LL-37: A new important molecule in the pathophysiology of systemic lupus erythematosus
Journal of Translational Autoimmunity, 2020 Cathelicidin LL-37 is an antimicrobial peptide that is synthesized by epithelial cells, neutrophils, or lymphocytes and act as an essential defense mechanism against bacterial, viral, or fungi infection of eukaryotic organisms.
Alejandro Moreno-Angarita +2 more
doaj +1 more source
Journal of Immunology Research, Volume 2017, Issue 1, 2017., 2017 The goal of the present study was to determine whether peptidylarginine deiminase PAD2 and PAD4 enzymes are present in Balb/c mouse salivary glands and whether they are able to citrullinate Ro and La ribonucleoproteins. Salivary glands from Balb/c mice were cultured in DMEM and supplemented with one of the following stimulants: ATP, LPS, TNF, IFNγ, or ...
Mayra Rodríguez-Rodríguez +8 more
wiley +1 more source
Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2018 Desde el punto de vista inmunológico esta situación se agrupa bajo el título de 'Enfermedades en las que el suero contiene antígenos tejido-localizantes".
Hernán Mendoza Hoyos
doaj +1 more source
An Animal Model Using Metallic Ions to Produce Autoimmune Nephritis
Journal of Immunology Research, Volume 2015, Issue 1, 2015., 2015 Autoimmune nephritis triggered by metallic ions was assessed in a Long‐Evans rat model. The parameters evaluated included antinuclear autoantibody production, kidney damage mediated by immune complexes detected by immunofluorescence, and renal function tested by retention of nitrogen waste products and proteinuria.
Roxana Ramírez-Sandoval +9 more
wiley +1 more source
Soluble Fas and the −670 Polymorphism of Fas in Lupus Nephritis
International Journal of Nephrology, Volume 2014, Issue 1, 2014., 2014 This study was performed to clarify the role of soluble Fas (sFas) in lupus nephritis (LN) and establish a potential relationship between LN and the −670 polymorphism of Fas in 67 patients with systemic lupus erythematosus (SLE), including a subset of 24 LN patients with proteinuria. Additionally, a group of 54 healthy subjects (HS) was included.
Juan José Bollain-y-Goytia +7 more
wiley +1 more source
Case Reports in Genetics, Volume 2013, Issue 1, 2013., 2013 Fibrodysplasia ossificans progressiva (FOP) is an exceptionally rare genetic disease that is characterised by congenital malformations of the great toes and progressive heterotopic ossification (HO) in specific anatomical areas. This disease is caused by a mutation in activin receptor IA/activin‐like kinase‐2 (ACVR1/ALK2).
Rafael Herrera-Esparza +10 more
wiley +1 more source
Posttranslational Protein Modification in the Salivary Glands of Sjögren’s Syndrome Patients
Autoimmune Diseases, Volume 2013, Issue 1, 2013., 2013 The present study investigated posttranslational reactions in the salivary glands of patients with Sjögren’s syndrome. We analysed the biopsies of primary Sjögren’s patients using immunohistochemistry and a tag‐purified anticyclic citrullinated protein (CCP) antibody to detect citrullinated peptides, and the presence of peptidylarginine deiminase 2 ...
Rafael Herrera-Esparza +8 more
wiley +1 more source
Autoantibodies in Senear‐Usher Syndrome: Cross‐Reactivity or Multiple Autoimmunity?
Autoimmune Diseases, Volume 2012, Issue 1, 2012., 2012 Senear‐Usher syndrome or pemphigus erythematosus is a pathology that overlaps clinically and serologically with pemphigus foliaceus and lupus erythematosus. Skin biopsies of patients with pemphigus erythematosus reveal acantholysis and deposits of immunoglobulins in desmosomes, and they are positive in the lupus band test.
María Elena Pérez-Pérez +3 more
wiley +1 more source
Autoantibodies production and immunological abnormalities after bariatric surgery
Journal of Translational Autoimmunity, 2019 Objective: Bariatric surgery is a widely used procedure for the treatment of obesity. Our aim is to describe the main immunological changes in patients who undergo bariatric surgery.
Gabriel J. Tobón +11 more
doaj +1 more source
Hipertiroidismo en niños y adolescentes: experiencia en un hospital universitario en Colombia
Biomédica: revista del Instituto Nacional de Salud, 2022 Introducción. El hipertiroidismo es una condición heterogénea caracterizada por la producción excesiva de hormonas tiroideas. Su aparición en la edad pediátrica representa un reto diagnóstico y terapéutico. Objetivo.
Judith Sofía García +5 more
doaj +1 more source