Results 21 to 30 of about 577 (166)
An Animal Model Using Metallic Ions to Produce Autoimmune Nephritis
Journal of Immunology Research, Volume 2015, Issue 1, 2015., 2015 Autoimmune nephritis triggered by metallic ions was assessed in a Long‐Evans rat model. The parameters evaluated included antinuclear autoantibody production, kidney damage mediated by immune complexes detected by immunofluorescence, and renal function tested by retention of nitrogen waste products and proteinuria.
Roxana Ramírez-Sandoval +9 more
wiley +1 more source
Soluble Fas and the −670 Polymorphism of Fas in Lupus Nephritis
International Journal of Nephrology, Volume 2014, Issue 1, 2014., 2014 This study was performed to clarify the role of soluble Fas (sFas) in lupus nephritis (LN) and establish a potential relationship between LN and the −670 polymorphism of Fas in 67 patients with systemic lupus erythematosus (SLE), including a subset of 24 LN patients with proteinuria. Additionally, a group of 54 healthy subjects (HS) was included.
Juan José Bollain-y-Goytia +7 more
wiley +1 more source
Case Reports in Genetics, Volume 2013, Issue 1, 2013., 2013 Fibrodysplasia ossificans progressiva (FOP) is an exceptionally rare genetic disease that is characterised by congenital malformations of the great toes and progressive heterotopic ossification (HO) in specific anatomical areas. This disease is caused by a mutation in activin receptor IA/activin‐like kinase‐2 (ACVR1/ALK2).
Rafael Herrera-Esparza +10 more
wiley +1 more source
Posttranslational Protein Modification in the Salivary Glands of Sjögren’s Syndrome Patients
Autoimmune Diseases, Volume 2013, Issue 1, 2013., 2013 The present study investigated posttranslational reactions in the salivary glands of patients with Sjögren’s syndrome. We analysed the biopsies of primary Sjögren’s patients using immunohistochemistry and a tag‐purified anticyclic citrullinated protein (CCP) antibody to detect citrullinated peptides, and the presence of peptidylarginine deiminase 2 ...
Rafael Herrera-Esparza +8 more
wiley +1 more source
Autoantibodies production and immunological abnormalities after bariatric surgery
Journal of Translational Autoimmunity, 2019 Objective: Bariatric surgery is a widely used procedure for the treatment of obesity. Our aim is to describe the main immunological changes in patients who undergo bariatric surgery.
Gabriel J. Tobón +11 more
doaj +1 more source
Hipertiroidismo en niños y adolescentes: experiencia en un hospital universitario en Colombia
Biomédica: revista del Instituto Nacional de Salud, 2022 Introducción. El hipertiroidismo es una condición heterogénea caracterizada por la producción excesiva de hormonas tiroideas. Su aparición en la edad pediátrica representa un reto diagnóstico y terapéutico. Objetivo.
Judith Sofía García +5 more
doaj +1 more source
Autoantibodies in Senear‐Usher Syndrome: Cross‐Reactivity or Multiple Autoimmunity?
Autoimmune Diseases, Volume 2012, Issue 1, 2012., 2012 Senear‐Usher syndrome or pemphigus erythematosus is a pathology that overlaps clinically and serologically with pemphigus foliaceus and lupus erythematosus. Skin biopsies of patients with pemphigus erythematosus reveal acantholysis and deposits of immunoglobulins in desmosomes, and they are positive in the lupus band test.
María Elena Pérez-Pérez +3 more
wiley +1 more source
The Caspase Pathway as a Possible Therapeutic Target in Experimental Pemphigus
Autoimmune Diseases, Volume 2011, Issue 1, 2011., 2011 Apoptosis plays a role in pemphigus IgG‐dependent acantholysis; theoretically, the blockade of the caspase pathway could prevent the blistering that is caused by pemphigus autoantibodies. Using this strategy, we attempted to block the pathogenic effect of pemphigus IgG in Balb/c mice by using the caspase inhibitor Ac‐DEVD‐CMK.
Deyanira Pacheco-Tovar +4 more
wiley +1 more source
Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2020 La deficiencia y el exceso de yodo tienen graves consecuencias para la salud humana y se han asociado con la presencia de bocio, hipotiroidismo, hipertiroidismo, cáncer de tiroides, nódulos y autoinmunidad tiroideos, así como un pobre desarrollo mental ...
H. Vargas Uricoechea +2 more
doaj +1 more source
Blau Syndrome‐Related CARD15/NOD2 Mutations Are Not Linked to Idiopathic Uveitis in Spanish Patients
Disease Markers, Volume 27, Issue 1, Page 1-5, 2009., 2009 Uveitis is a clinical feature of the Blau syndrome, a disease linked to CARD15 (also referred to as NOD2) mutations. Three main mutations in this gene (R334W, R334Q and L469F) have been reported as Blau syndrome risk factors, a disease that manifests uveitis as one of its clinical features.
Noelia Rodríguez-Pérez +4 more
wiley +1 more source