Results 1 to 10 of about 19,896 (177)
Journal of Immunology Research, 2021 Vitamin D (calcidiol) deficiency in systemic lupus erythematosus (SLE) is more frequent than in healthy subjects (HS); it is associated with clinical activity and damage in SLE.
Mónica R. Meza-Meza +9 more
doaj +2 more sources
Mediators of Inflammation, 2013 Tumoral necrosis factor α plays a central role in both the inflammatory response and that of the immune system. Thus, its blockade with the so-called anti-TNF agents (infliximab, etanercept, adalimumab, certolizumab pegol, and golimumab) has turned into ...
Daniel Sánchez-Cano +4 more
doaj +2 more sources
Uncovering Genetic Variation in Systemic Lupus Erythematosus Risk Variants in Indigenous Peruvians. [PDF]
ACR Open RheumatolObjective Systemic lupus erythematosus (SLE) results in worse clinical outcomes among individuals of Amerindian descent. The genetic basis for this is uncertain, and there is a significant lack of genetic research focused on Amerindian ancestry populations.
Lanata CM +9 more
europepmc +2 more sources
Journal of Osteoporosis, 2015 Glucocorticoids (GCs) are the cornerstone of the therapy in many autoimmune and inflammatory diseases. However, it is well known that their use is a double edged sword, as their beneficial effects are associated almost universally with unwanted effects ...
Miguel Ortego-Jurado +6 more
doaj +2 more sources
Neumonía intersticial con características autoinmunes (IPAF): reporte de casos
Revista Argentina de Reumatología, 2021 IPAF agrupa individuos con EPID y otras características clínicas, serológicas o pulmonares que derivan de una condición autoinmune sistémica subyacente, pero no cumplen con los criterios reumatológicos actuales para una ETC.
Marcela María Usandivaras +2 more
doaj +1 more source
Arthritis &Rheumatology, Volume 75, Issue 6, Page 984-995, June 2023., 2023 Objective The present study was undertaken to longitudinally evaluate titers of antibodies against β2‐glycoprotein I (anti‐β2GPI) and domain 1 (anti‐D1), to identify predictors of variations in anti‐β2GPI and anti‐D1 titers, and to clarify whether antibody titer fluctuations predict thrombosis in a large international cohort of patients who were ...
Cecilia B. Chighizola +92 more
wiley +1 more source
BMC Molecular and Cell Biology, 2020 Introduction The clinical efficacy of specific interleukin-6 inhibitors has confirmed the central role of IL6 in rheumatoid arthritis (RA). However the local role of IL6, in particular in synovial fibroblasts (SF) as a direct cellular target to IL6/sIL6R
Alvaro Valin +10 more
doaj +1 more source
Enfermedades reumáticas y alergias, la dualidad del sistema inmunológico
Revista Alergia México, 2021 Las enfermedades reumáticas autoinmunes son trastornos multisistémicos que afectan principalmente las articulaciones y los músculos; algunos ejemplos de estas afecciones son la artritis reumatoide, el lupus eritematoso sistémico y el síndrome de Sjögren.
Gabriela Athziri Sánchez-Zuno +5 more
doaj +1 more source
TFAM-deficient mouse skin fibroblasts – an ex vivo model of mitochondrial dysfunction
Disease Models & Mechanisms, 2021 Mitochondrial dysfunction associates with several pathological processes and contributes to chronic inflammatory and ageing-related diseases. Mitochondrial transcription factor A (TFAM) plays a critical role in maintaining mtDNA integrity and function ...
Manuel J. Del Rey +7 more
doaj +1 more source
La importancia del laboratorio en el diagnóstico del síndrome de Sjögren primario
Revista de la Facultad de Ciencias Médicas de Córdoba, 2009 El síndrome de Sjögren (SS) es una enfermedad autoinmune sistémica que se caracteriza fundamentalmente por la presencia de xeroftalmía y xerostomía debido a la infiltración de las glándulas lagrimales y salivares por células linfoplasmocitarias. Al igual
Pilar Brito-Zerón +6 more
doaj +1 more source