Results 101 to 110 of about 309,563 (300)

Autologous chondrocyte implantation for cartilage repair: current perspectives

, 2015
Johannes Zellner,1 Werner Krutsch,1 Christian G Pfeifer,1 Matthias Koch,1 Michael Nerlich,1 Peter Angele1,2 1Department of Trauma Surgery, University Medical Center Regensburg, Regensburg, Germany; 2Sporthopaedicum, Regensburg, Germany Abstract: Over ...
Koch M, Nerlich M, Zellner J, Pfeifer CG, Krutsch W, Angele P   +5 more
core  

Autologous vs. allogenic mesenchymal progenitor cells for the reconstruction of critical-sized segmental tibial bone defects in aged sheep [PDF]

, 2013
Mesenchymal progenitor cells (MPCs) represent an attractive cell population for bone tissue engineering. Their special immunological characteristics suggest that MPCs may be used in an allogenic application. The objective of this study was to compare the
Woodruff, M.A., Saifzadeh, S., Woodruff, Maria A., Hutmacher, D.W., Hutmacher, Dietmar, Nerlich, M, Saifzadeh, Siamak, Schuetz, M.A., Schuetz, Michael, Morris, A.J., Morris, Anthony, Epari, Devakar, Epari, D.R., Berner, A., Reichert, J.C., Nerlich, M., Berner, Arne   +16 more
core   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Autologous fat grafting: use of closed syringe microcannula system for enhanced autologous structural grafting

, 2013
Robert W Alexander,1 David Harrell2 1Department of Surgery, School of Medicine and Dentistry, University of Washington, Seattle, WA, USA; 2Harvest-Terumo Inc, Plymouth, MA, USA Objectives: Provide background for use of acquiring autologous adipose tissue
Alexander RW, Harrell DB
core  

Phase II study of ERC1671 plus bevacizumab versus bevacizumab plus placebo in recurrent glioblastoma: interim results and correlations with CD4+ T-lymphocyte counts

CNS Oncology, 2018
Aim: ERC1671 is an allogeneic/autologous therapeutic glioblastoma (GBM) vaccine – composed of whole, inactivated tumor cells mixed with tumor cell lysates derived from the patient and three GBM donors.
Daniela A Bota, Jinah Chung, Manisha Dandekar, Jose A Carrillo, Xiao-Tang Kong, Beverly D Fu, Frank PK Hsu, Axel H Schönthal, Florence M Hofman, Thomas C Chen, Raphael Zidovetzki, Chrystel Pretto, Ankie Strik, Virgil EJC Schijns, Apostolos Stathopoulos   +14 more
doaj   +1 more source

Arthroscopic Technique for Autologous Minced Cartilage Implantation for Focal Lesions of the Capitellum Humeri of the Elbow: A Technical Note. [PDF]

Arthrosc Tech
Abstract Focal cartilage defects of the capitellum humeri are frequently underestimated, despite their substantial contribution to elbow pain and functional impairment in young and physically active patients. Arthroscopic autologous minced cartilage implantation is a single‐stage biological cartilage repair technique that has shown favorable clinical ...
Leschinger T, Ott N, Wegmann S, Weber M, Müller LP, Babasiz T.   +5 more
europepmc   +2 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Interaction between Dimethylpolysiloxane and Autologous Plasma Triggering in Vitro Inflammation in Cultured PBMC [PDF]

, 2018
The data obtained from this study try to explain the mechanism of cellular immune response of dmps-injected recipients with in vitro-based method to get the description of immune responses that occurs in the body due to exposure to dmps which can lead to
F, Mujadid, Harlim, Ago, H, Wibowo
core   +1 more source

Autologous Iliac Crest Bone Graft After Anterior Cruciate Ligament Reconstruction Failure in Patients With Both Femoral and Tibial Tunnel Enlargement. [PDF]

Arthrosc Tech
Abstract Tunnel enlargement is a common challenge in revision anterior cruciate ligament reconstruction and compromises graft fixation and biological integration. Traditional 2‐stage revision procedures prolong treatment duration and increase patient morbidity.
Wu A, He Y, Xiang S, Xiong C, Zhu W.
europepmc   +2 more sources

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

Advanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung, Alexander Beer, Susmita Ghosh, Ekaterina Pylaeva, Belal Alshaar, Tobias Tertel, Nils Bastian Leimkühler, Thomas Schroeder, Janine Gronewold, Nina Hagemann, Ayan Mohamud Yusuf, Benedikt Frank, Yiqiao Zhang, Dennis Nagel, Kim Schloeßer, Laura Karsch, Emily Hedtfeld, Sabrina Lohmann, Kathrin Blank, Andreas Kraus, Max Krumbein, Nastassia Kabankova, Hongxiao Wang, Almke Bader, Mathis Richter, Fengjun Zhang, Raphael Chevre, Bernd Giebel, Stephan Lang, Anika Grüneboom, Daniela Maier‐Begandt, Anja Hasenberg, Oliver Soehnlein, Hans Christian Reinhardt, Sven Heiles, Jianxu Chen, Jadwiga Jablonska, Albert Sickmann, Dirk M. Hermann, Matthias Gunzer   +39 more
wiley   +1 more source