Results 171 to 180 of about 612,706 (397)
Fragment Autoantigens Stimulated T‐Cell‐Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine
A personalized whole tumor cell vaccine (FAST) is developed to address immunosuppressive tumor microenvironments and genomic instability‐driven heterogeneity. Irradiation and cryoablation‐treated tumor cells generate fragmented antigens (FAs) that activate broad‐spectrum antigen presentation via upregulated immunogenic cell death, MHC‐I, and damage ...
Yuan Li+14 more
wiley +1 more source
DESTRUCTION OF EPIDERMAL CELLS IN VITRO BY AUTOLOGOUS SERUM FROM NORMAL ANIMALS [PDF]
Paul I. Terasaki, C. C. Chamberlain
openalex +1 more source
Immunity to self co-generates regulatory T cells [PDF]
Immune responses to self are kept in check by tolerance mechanisms, including suppression by regulatory T cells (Tregs). The defective generation of Tregs specific for self-antigens may lead to autoimmune disease.
Bo Han Lee+8 more
core +1 more source
CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu+14 more
wiley +1 more source
The Immune Response to Circulating Autologous Hepatocellular Antigens [PDF]
A. U. Sargent, J. Myers, M. Richter
openalex +1 more source
This study introduces a novel, safe, and effective surgical technique: Cranial bone transport (CBT) to improve traumatic brain injury (TBI) outcomes in rats. CBT significantly accelerated skull defect bone repair in addition to its promoting effects on neurological function recovery. This work provides an alternative therapy for patients suffering from
Shanshan Bai+20 more
wiley +1 more source
AUTOLOGOUS BONE‐MARROW TRANSFUSION FOLLOWING CHEMOTHERAPY [PDF]
Leo M. Meyer+2 more
openalex +1 more source
This study employs neutrophils for the precise delivery of anti‐CD47 antibodies, combined with bacterial outer membrane vesicles, to enhance macrophage phagocytic function in the tumor microenvironment. This approach effectively activates T‐cell anti‐tumor immune responses and significantly reduces the risk of postoperative tumor recurrence and ...
Meng Guan+15 more
wiley +1 more source