Results 11 to 20 of about 84,027 (262)

The Incidence and Clinical Relevance of Graft Hypertrophy After Matrix-Based Autologous Chondrocyte Implantation [PDF]

open access: yes, 2011
Background: Graft hypertrophy is the most common complication of periosteal autologous chondrocyte implantation (p-ACI). Purpose: The aim of this prospective study was to analyze the development, the incidence rate, and the persistence of graft ...
Matthias F. Pietschmann   +13 more
core   +1 more source

Bone Marrow Mononuclear Cell Count does not Predict Neutrophil and Platelet Recovery following Autologous Bone Marrow Transplant: Value of the Colony-Forming Unit Granulocyte-Macrophage (CFU-GM) Assay

open access: yesCell Transplantation, 1997
The common use of the marrow autograft mononuclear cell (MNC) count derives from positive correlative studies following allogeneic transplantation and from earlier conflicting data regarding the value of the bone marrow autograft colony-forming unit ...
Fahad Al-Fiar   +5 more
doaj   +1 more source

High dose melphalan is an adequate preparative regimen for autologous hematopoietic stem cell transplantation in relapsed/refractory lymphoma

open access: yesHematology, 2022
Introduction High-dose melphalan (HD-Mel) has been successfully employed in autografting patients with multiple myeloma. An advantage of this regimen is that the total dose of Mel can be delivered in a single day, being particularly useful when non ...
José A. Fernández-Gutiérrez   +11 more
doaj   +1 more source

Blood Stem Cell Collection: Factors Influencing the Recovery of Granulocyte-Macrophage Colony Forming Cells

open access: yesCell Transplantation, 1996
We evaluated data from all blood cell (BC) collections performed in our institution between 1989 and 1995 to determine factors influencing the outcome of collection. One hundred and thirty-three collections were performed on 106 patients.
Kevin Imrie   +5 more
doaj   +1 more source

Type 2 diabetes mellitus duration and obesity alter the efficacy of autologously transplanted bone marrow‐derived mesenchymal stem/stromal cells

open access: yesStem Cells Translational Medicine, 2021
Human bone marrow‐derived mesenchymal stem/stromal cells (BM‐MSCs) represent promising stem cell therapy for the treatment of type 2 diabetes mellitus (T2DM), but the results of autologous BM‐MSC administration in T2DM patients are contradictory.
Liem Thanh Nguyen   +20 more
doaj   +1 more source

Functional recovery of a 41-year-old quadriplegic spinal cord injury patient following multiple intravenous infusions of autologous adipose-derived mesenchymal stem cells: a case report

open access: yesFrontiers in Transplantation, 2023
Spinal cord injury (SCI) is a debilitating disease with clinical manifestations ranging from incomplete neurological deficits affecting sensory and motor functions to complete paralysis.
Ridhima Vij   +6 more
doaj   +1 more source

Ethical and Regulatory Challenges with Autologous Adult Stem Cells:A Comparative Review of International Regulations [PDF]

open access: yes, 2015
Cell and tissue-based products, such as autologous adult stem cells, are being prescribed by physicians across the world for diseases and illnesses that they have neither been approved for or been demonstrated as safe and effective in formal clinical ...
Lysaght, T   +9 more
core   +1 more source

Humanized Mouse Model as a Novel Approach in the Assessment of Human Allogeneic Responses in Organ Transplantation

open access: yesFrontiers in Immunology, 2021
The outcome of organ transplantation is largely dictated by selection of a well-matched donor, which results in less chance of graft rejection. An allogeneic immune response is the main immunological barrier for successful organ transplantation.
Ashwin Ajith   +6 more
doaj   +1 more source

Growth factors for clinical-scale expansion of human articular chondrocytes : Relevance for automated bioreactor systems [PDF]

open access: yes, 2007
The expansion of chondrocytes in automated bioreactors for clinical use requires that a relevant number of cells be generated, starting from variable initial seeding densities in one passage and using autologous serum.
Candrian, Christian   +7 more
core   +1 more source

Platelet autologous growth factors decrease the osteochondral regeneration capability of a collagen-hydroxyapatite scaffold in a sheep model [PDF]

open access: yes, 2010
Current research aims to develop innovative approaches to improve chondral and osteochondral regeneration. The objective of this study was to investigate the regenerative potential of platelet-rich plasma (PRP) to enhance the repair process of a collagen-
Milena Fini   +15 more
core   +1 more source

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