Results 41 to 50 of about 84,027 (262)

Genetic Susceptibility in Endothelial Injury Syndromes after Hematopoietic Cell Transplantation and Other Cellular Therapies: Climbing a Steep Hill

Current Issues in Molecular Biology
Hematopoietic stem cell transplantation (HSCT) remains a cornerstone in the management of patients with hematological malignancies. Endothelial injury syndromes, such as HSCT-associated thrombotic microangiopathy (HSCT-TMA), veno-occlusive disease ...
Paschalis Evangelidis, Nikolaos Evangelidis, Panagiotis Kalmoukos, Maria Kourti, Athanasios Tragiannidis, Eleni Gavriilaki   +5 more
doaj   +1 more source

Combined autologous and allograft limbal cell transplantation with penetrating keratoplasty in a case of chemical corneal burn patient

Oman Journal of Ophthalmology, 2009
A patient with chemical corneal burn presented two months after the acute episode of chemical injury to his right eye (OD) and was diagnosed with severe limbal stem cell deficiency and with vascularized corneal opacity OD. Limbal cell transplantation and
Sandip Mitra
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Autologous bone-marrow mesenchymal cell induced chondrogenesis (MCIC)

, 2016
Degenerative and traumatic articular cartilage defects are common, difficult to treat, and progressive lesions that cause significant morbidity in the general population.
Ahmed, S., Kim, S., Shetty, A., Lee, D., Huh, S.   +4 more
core   +1 more source

Material of Choice in Pediatric Cranioplasty

Indian Journal of Neurosurgery, 2021
Background Current evidence is lacking regarding the optimum material required for cranioplasty in the pediatric population when native bone cannot be replaced.
Anooja Abdul Salam, Imogen Ibbett, Nova Thani   +2 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Efficacy of consolidation high-dose chemotherapy with ifosfamide, carboplatin and etoposide (HD-ICE) followed by autologous peripheral blood stem cell rescue in chemosensitive patients with metastatic soft tissue sarcomas [PDF]

, 2006
Background: Prognosis of patients with metastatic soft tissue sarcomas (MSTS) is poor even after response to doxorubicin-based chemotherapy. We report phase II data of highdose chemotherapy and peripheral blood stem cell (PBSC) rescue in patients with ...
Hentrich, M., Licht, Thomas, Straka, Christian, Rolf-Dieter Issels, Wendtner, Clemens-Martin, Marcus Schlemmer, Hiddemann, Wolfgang, Abdel-Rahman, Sultan, Sultan Abdel-Rahman, Issels, Rolf-Dieter, Salat, C., Baumert, Jens, Straka, C., Hiddemann, W., Falk, Martin, Issels, R.D., Wolfgang Hiddemann, Martin Falk, Jens Baumert, Falk, M., Thomas Licht, Schlemmer, M., Marcus Hentrich, Licht, T., Salat, Christoph, Christoph Salat, Abdel-Rahman, S., Clemens-Martin Wendtner, Schlemmer, Marcus, Wendtner, C.M., Baumert, J.J., Hentrich, Marcus, Christian Straka   +32 more
core   +1 more source

Autologous Blood Donation

Anesthesiology Clinics of North America, 2005
Preoperative autologous blood donation has become accepted as a standard practice in elective surgery. Subsequent improvements in blood safety and evolving surgical techniques resulting in less blood loss have caused a national decline in preoperative autologous blood donation by approximately 50%.
openaire   +3 more sources

Biological topicals in ocular surface disorders

Indian Journal of Ophthalmology
Topical biological agents represent a significant advancement in the treatment of ocular surface diseases, offering a regenerative and therapeutic approach beyond conventional therapies.
Sridevi Nair, Murugesan Vanathi, Radhika Tandon   +2 more
doaj   +1 more source

Autologous non-cultured keratinocyte cell suspension in non-healing diabetic ulcers: A preliminary study

Journal of Family Medicine and Primary Care, 2020
Background: Diabetic ulcers are a common morbidity associated with poorly controlled glycemic status. Most patients often have neuropathy and vasculopathy as the etiology behind such ulcers.
Shruti Barnwal, Ravi Kant, Poonam Yadav
doaj   +1 more source