Results 161 to 170 of about 2,189,298 (239)

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Composition of allogeneic equine orthobiologics and their repeated intra‐articular administrations

Equine Veterinary Journal, EarlyView.
Abstract Background Orthobiologics such as platelet‐rich plasma (PRP) and alpha‐2‐macroglobulin (A2MG) are increasingly used for equine musculoskeletal injuries. However, their composition and safety with repeated allogeneic intra‐articular administration remain poorly investigated.
Yanne Van Reusel, Sarah Y. Broeckx, Anna Carolo, Marco Patruno, Jonas Steenbrugge, Jimmy Saunders, Enrico Gugliandolo, Jan H. Spaas   +7 more
wiley   +1 more source

Computed tomography long‐term follow‐up of a facial fracture involving the orbit and paranasal sinus

Equine Veterinary Journal, EarlyView.
Abstract Background Fractures of the facial bones involving the orbit are challenging conditions that require surgical treatment. Objectives To describe preoperative and postoperative clinical and computed tomographic findings of an orbital rim fracture repaired using a reconstruction plate. Study Design Case report.
A. Kalinovskiy, C. Lischer, J. C. Eule, K. Thieme, K. Mählmann   +4 more
wiley   +1 more source

Guidelines for the administration of blood and blood components

, 2004
National Blood Users Group
core  

Agreement between invasive and oscillometric blood pressure measurements during controlled haemorrhage in anaesthetised horses

Equine Veterinary Journal, EarlyView.
Abstract Background Defining the reliability of oscillometry (NIBP) for measuring mean arterial pressure (MAP) during normotension and hypovolaemic hypotension could help with cardiovascular monitoring and management in horses anaesthetised in dorsal recumbency.
Colleen Hickey, Alonso Guedes, Jessica Byrne, Eduardo Hatschbach, Brian Walters, Aaron Rendahl, Caitlin Tearney   +6 more
wiley   +1 more source

Electrochemical Valence‐Regulated Biomimetic Nanozymes for Breast Cancer Metabolism Inhibition and Potentiated Catalytic Immunotherapy

Exploration, EarlyView.
MnOx nanozymes face low tumoricidal activity and PD‐L1‐mediated immune attenuation. Electrochemically regulated M‐MnOx with high oxidase activity was TCM‐wrapped into TMO. TMO targets tumors, triggers ICD, activates cGAS‐STING, antagonizes PD‐L1, and suppresses tumor recurrence, providing new insights for Mn‐based nanomaterials.
You Pan, Wei Cai, Meng Suo, Xiangqin Meng, Shengxin Ye, Yuping Tan, Xianqing Wei, Mingpu Yang, Pengyuan Qi, Zihang Yu, Kelong Fan, Shipeng Ning   +11 more
wiley   +1 more source

Support and destigmatization in early pregnancy loss in Spain

Feminist Anthropology, EarlyView.
Abstract Early miscarriages are a frequent reproductive event, often silenced and shrouded in stigma. Feminist anthropology has pointed out how such losses challenge the widespread Euro‐American social representations of motherhood and pregnancy, as well as societal unease with death.
Giulia Colavolpe‐Severi, Alexandra Desy, Carolina Remorini   +2 more
wiley   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Platelet‐Rich Fibrin (PRF) Application and Education in US Graduate Programs: A Cross‐Sectional Study

Journal of Dental Education, EarlyView.
ABSTRACT The aim of this cross‐sectional study was to assess platelet‐rich fibrin (PRF) application and education in clinical use among US graduate periodontology, endodontic, and oral and maxillofacial surgery programs. A survey questionnaire was electronically distributed to 84 oral and maxillofacial surgery (OMFS), 46 endodontic, and 46 ...
Elena Furman, Mark Piroutek, T. Roma Jasinevicius, Andre Paes B. da Silva   +3 more
wiley   +1 more source