Results 181 to 190 of about 2,189,298 (239)
Cranial Vault and Scalp Reconstruction Utilizing Anterolateral Thigh Free Tissue Transfer
The Laryngoscope, EarlyView.The anterolateral thigh free flap with perforator harvest and minimal access recipient vessel procurement technique offers an adaptable and effective reconstructive option for a wide variety of complex scalp and cranial vault defects. There were no significant differences in outcomes or complications of the three flap types analyzed (fasciocutaneous ...
Conrad Blunck +7 more
wiley +1 more source
Lasers in Surgery and Medicine, EarlyView.ABSTRACT Objective This study aimed to evaluate whether the combination of photobiomodulation and platelet‐rich plasma therapy provides superior anti‐inflammatory and joint‐protective effects compared to individual treatments in an experimental model of osteoarthritis.
Anne Missrie +5 more
wiley +1 more source
Organoid Coculture Models for Cancer Research and Immunotherapy
Med Research, EarlyView.This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang +9 more
wiley +1 more source
Senotherapeutics for Knee Osteoarthritis
Medicinal Research Reviews, EarlyView.ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman +6 more
wiley +1 more source
Recent Advances in Cryogel Applications for Musculoskeletal Regeneration
Medicinal Research Reviews, EarlyView.ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim +4 more
wiley +1 more source
Medicine Advances, EarlyView.This study utilized bibliometrics to summarize research activity and global collaboration in impactful microfracture literature. The United States is the leading contributor to microfracture research, accounting for 34% of the top 100 cited publications, followed by Germany (10%) and Italy (9%).
Boshen Shu
wiley +1 more source
Neurourology and Urodynamics, EarlyView.ABSTRACT Background Achieving continence in patients with neurogenic bladder is a difficult goal especially when stress urinary incontinence (SUI) due to intrinsic sphincter deficiency is involved. Two techniques are commonly used in that setting, but they have never been directly compared: the artificial urinary sphincter (AUS) and the fascial ...
Alicia Blondeau +7 more
wiley +1 more source
Neuroprotection, EarlyView.Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji +4 more
wiley +1 more source
Hemophilia A: An Ideal Disease for Prenatal Therapy
Prenatal Diagnosis, EarlyView.ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada +2 more
wiley +1 more source