Results 181 to 190 of about 238,159 (194)

Autologous haematopoietic stem cell transplantation for multiple sclerosis in the UK: A 20‐year retrospective analysis of activity and haematological outcomes from the British Society of Blood and Marrow Transplantation and Cellular Therapy (BSBMTCT)

open access: yesBritish Journal of Haematology, EarlyView.
We report the UK experience of autologous haematopoietic stem cell transplantation (AHSCT) for multiple sclerosis (MS) in 364 patients. In our observational study, transplant‐related mortality was 1.4%, Epstein–Barr virus reactivation occurred in 75.9%, while disability progression‐free survival was 83.5% at 2 years post‐AHSCT and 62.4% at 5 years.
Majid Kazmi   +18 more
wiley   +1 more source

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

Activation of autophagy mediated by PI3K/Akt/mTOR signalling cascade alleviates impaired adipose‐derived stem cell osteogenesis in a diabetic microenvironment

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Advanced glycation end products (AGEs) contribute to the onset and advancement of diabetic osteoporosis (DOP). Adipose‐derived stem cells (ASCs) have garnered attention in the field of bone renewal; the mechanisms leading to decreased osteogenesis within a diabetic environment are not fully understood.
Fangzhi Lou   +8 more
wiley   +1 more source

Hemostatic activation during cardiopulmonary bypass with different aprotinin dosages in pediatric patients having cardiac operations [PDF]

open access: yes, 1993
Baranky, A.   +7 more
core  

Monovalent glycoconjugates of sulforaphane prevent inflammation induced by lipopolysaccharide in human dendritic cells by inhibiting NF‐ĸB signalling pathway

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Sulforaphane (SFN) has notable health benefits but faces challenges due to its poor solubility and delivery. This study investigates SFN‐glycoconjugates effects on lipopolysaccharide (LPS)‐induced inflammation in dendritic cells (DCs). With the aiming to enhance their therapeutic potential against inflammatory diseases.
Camila Leiva‐Castro   +5 more
wiley   +1 more source

Maxillary Sinus Floor Augmentation With Autogenous Bone Versus Bovine Bone Mineral Mixed With 25% Autogenous Bone: A 1‐Year Multicenter, Split‐Mouth, Randomized Controlled Trial

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To compare autogenous bone (AB) harvested from the mandibular ramus or a mixture of bovine bone mineral (BBM) with 25% locally harvested autogenous bone chips from the maxilla for maxillary sinus floor augmentation (MSFA). Material and Methods Patients requiring bilateral MSFA and implant placement were enrolled in this study ...
Anouck Jue   +5 more
wiley   +1 more source

Premature Bone Resorption in Vertical Ridge Augmentation: A Systematic Review and Network Meta‐Analysis of Randomised Clinical Trials

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To systematically appraise the evidence on premature ridge resorption following various vertical ridge augmentation (VRA) techniques in healthy adult patients undergoing staged VRA procedures. The study aimed to identify VRA techniques resulting in the least premature bone resorption and to rank them using Bayesian Network Meta ...
Faisal Faihan Alotaibi   +5 more
wiley   +1 more source

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