Results 71 to 80 of about 1,361,764 (281)

Review of articular cartilage repair techniques and their application in the horse

Equine Veterinary Journal, EarlyView.
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton, Brad B. Nelson, Laurie R. Goodrich   +2 more
wiley   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

3D printing of cell‐free implants: A promising avenue for cartilage regeneration and joint preservation

Interdisciplinary Medicine, EarlyView.
This article explores the potential of 3D‐printed, cell‐free implants or devices for cartilage regeneration. It highlights the benefits of using biomaterial‐driven activation and modulation of ESCPs for endogenous healing of heterogeneous tissues, addressing challenges in implant design, repair mechanisms, and regulatory hurdles to create scalable ...
Liangbin Zhou, Shangsi Chen, Boguang Yang, Yiting Lei, Hegeng Li, Haoyue Luo, Xiaoshuai Wang, Qiongjiao Zeng, Jiahui Lai, Fei Jin, Rocky S. Tuan, Zhong Alan Li   +11 more
wiley   +1 more source

Autologous Bone Marrow Transplantation.

مجلة جامعة دمشق للعلوم الطبية
Background: Control of the active pharmaceutical ingredient plays a crucial role in ensuring the required efficacy. Therefore, a new accurate, reproducible, and green RP-HPLC method was developed for determining Gatifloxacin in bulk and eye drops ...
Ola Mahmod Younes
doaj  

Prognostic Significance of Peripheral Blood Neutrophil‐To‐Lymphocyte Ratio (NLR), Monocyte‐To‐Lymphocyte Ratio (MLR), and Platelet‐To‐Lymphocyte Ratio (PLR) in Patients With Multiple Myeloma: A Retrospective Cohort Study

Journal of Clinical Laboratory Analysis, EarlyView.
This graphical abstract illustrates the prognostic significance of systemic inflammatory markers in Multiple Myeloma (MM). The left panel depicts the immunosuppressive tumor microenvironment, where abundant neutrophils and M2 macrophages promote MM cell survival while lymphocytes are depleted.
Lihong Zhang, Bing Ma, Jingyu Zhang
wiley   +1 more source

Mesenchymal Stromal Cell-Based Treatment of Jaw Osteoradionecrosis in Swine

Cell Transplantation, 2012
Jaw osteoradionecrosis (ORN) is a common and serious complication of radiation therapy for head and neck cancers. Bone marrow mesenchymal stromal cells (BMMSCs) are multipotent postnatal stem cells and have been widely used in clinical therapies.
Junji Xu, Zongmei Zheng, Dianji Fang, Runtao Gao, Yi Liu, Zhipeng Fan, Chunmei Zhang, Songtao Shi, Songlin Wang   +8 more
doaj   +1 more source

Autologous bone-marrow mesenchymal cell induced chondrogenesis (MCIC)

, 2016
Degenerative and traumatic articular cartilage defects are common, difficult to treat, and progressive lesions that cause significant morbidity in the general population.
Ahmed, S., Kim, S., Shetty, A., Lee, D., Huh, S.   +4 more
core   +1 more source

Spheroid‐based matrix‐induced autologous chondrocyte implantation combined with autologous bone grafting restores physiological cartilage and subchondral bone properties in osteochondral knee defects ‐ An MRI‐based analysis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aimed to evaluate the radiological and patient‐reported outcome measures (PROMs) following spheroid‐based matrix‐induced autologous chondrocyte implantation combined with autologous bone grafting (MABCI) for the treatment of osteochondral defects of the knee.
Stephan Oehme, Benjamin Bartek, Janne Callsen, Jessica Schallock, Tobias Winkler, Thorsten Diekhoff, Tobias Jung, Danko Dan Milinkovic   +7 more
wiley   +1 more source

Evaluation of the Repair of Bone Defect after Bone Marrow Stromal Cell Transplantation in Rat

Journal of Fasa University of Medical Sciences, 2013
Background & Objective: Bone marrow stromal cells (BMSCs) are multipotent stem cells that can proliferate and differentiate into osteogenic cells . T his study aimed to investigate the effects of BMSC transplantation for the repair of bone defects in the
Roghayeh Rezaei, Soheila Ebrahimi, Seyyed Homayoun Sadraie, Majid Naghdi, Giti Torkaman, Zabihollah Hasanzadeh, Gholamreza Kaka   +6 more
doaj  

Assessment of safety of additional transplantation of autologous bone marrow mononuclear cells in the combined treatment of coronary heart disease. Results from a randomized, blind, placebo-controlled trial (TAMIS)

Вестник трансплантологии и искусственных органов, 2019
Aim: to assess the safety of transplantation of autologous bone marrow mononuclear cells when performing coronary artery bypass grafting in the combined treatment of ischemic heart disease in patients with coronary and heart failure.Materials and methods.
V. V. Komok, N. S. Bunenkov, S. A. Beliy, V. M. Pizin, V. M. Kondratev, А. V. Dulaev, V. I. Lukashenko, A. E. Kobak, T. S. Maksimova, I. P. Sergienko, E. V. Parusova, L. A. Smirnova, E. V. Babenko, B. V. Afanasev, A. S. Nemkov, G. G. Khubulava   +15 more
doaj   +1 more source