Results 131 to 140 of about 1,311 (180)

Gene Therapy and Gene Editing in Type 1 Diabetes: CRISPR‐Based β‐Cell Replacement and Treg Immune Modulation Approaches

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5476-5491, July 2026.
ABSTRACT Background Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disease marked by the destruction of pancreatic β‐cells, resulting in lifelong dependence on exogenous insulin. Despite advances in insulin delivery and glucose monitoring technologies, patients remain at risk for acute and long‐term complications, underscoring the need for ...
Tzu‐Min Lin, Hui‐Fang Chang, Tzu‐Ching Lin, Cheng‐Han Lin, Yu‐Ling Sun, Chih‐Sheng Lin   +5 more
wiley   +1 more source

Ph‐Negative Acute Lymphoblastic Leukemia in the Older Adults: Biology, Therapeutic Strategies and Unmet Needs

European Journal of Haematology, Volume 117, Issue 1, Page 24-41, July 2026.
ABSTRACT Acute lymphoblastic leukaemia (ALL) in older adults represents a growing clinical challenge, driven by an ageing population, adverse disease biology, and reduced tolerance to intensive chemotherapy. Although pediatric‐inspired regimens have improved outcomes in younger adults with Philadelphia chromosome (Ph)‐negative ALL, survival in older ...
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Santino Caserta, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Marco Fiorillo, Nicola Amodio, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Factors Influencing Evidence‐Informed Symptom Management in Outpatient Malignant Hematology: A Qualitative Description of Patients' and Nurses' Experiences

Journal of Clinical Nursing, Volume 35, Issue 7, Page 3226-3241, July 2026.
ABSTRACT Aims To describe patients' and oncology nurses' experiences with symptom management care, and influential barriers and facilitators to enhancing evidence‐informed symptom management in an outpatient malignant hematology unit. Design A qualitative descriptive study embedded within an experience‐based co‐design approach.
Kylie Teggart, Denise Bryant‐Lukosius, Sarah E. Neil‐Sztramko, Tammy De Gelder, Kari Kolm, Cheryl Page, Rebecca Ganann   +6 more
wiley   +1 more source

The Underestimated Role of Environmental Factors in the Prevention of Invasive Fungal Disease: Experience From a European Childhood Cancer Centre

Mycoses, Volume 69, Issue 7, July 2026.
ABSTRACT Background Immunocompromised children with hematologic malignancies or undergoing allogeneic haematopoietic stem cell transplantation (HSCT) are at high risk for invasive fungal diseases (IFDs). Reported incidence varies considerably due to heterogeneous diagnostic criteria, antifungal strategies and environmental conditions.
Stefano Malvestiti, Felicia Andresen, Markus Hufnagel, Carsten Speckmann, Brigitte Strahm, Tobias Feuchtinger, Alexander Puzik   +6 more
wiley   +1 more source

Autologous Hematopoietic Stem Cell Transplantation for Multiple Myeloma in India [PDF]

Indian Journal of Hematology and Blood Transfusion, 2018
Rahul Naithani, Nitin Dayal, Reeta Rai, Sangeeta Pathak, Manoj Singh   +4 more
openaire   +2 more sources

Extranodal natural killer/T‐cell lymphoma: From fatal to curable

CA: A Cancer Journal for Clinicians, Volume 76, Issue 4, July/August 2026.
Abstract Extranodal natural killer (NK)/T‐cell lymphoma (ENKTCL) is one of the most aggressive non‐Hodgkin lymphomas characterized by NK‐cell or T‐cell origins, a geographic prevalence in Asian and South American populations, and Epstein–Barr virus (EBV) infection.
Jie Xiong, Yok‐Lam Kwong, Laurence de Leval, Shu‐Nan Qi, Choon Kiat Ong, Philippe Gaulard, Arnaud Jaccard, Steven M. Horwitz, Ye‐Xiong Li, Sai‐Juan Chen, Ritsuro Suzuki, Won Seog Kim, Wei‐Li Zhao   +12 more
wiley   +1 more source

Autologous Hematopoietic Stem Cell Transplant Recipient [PDF]

, 2020
openaire   +1 more source

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Complications of autologous hematopoietic stem cell transplantation

Haematologia, 2000
Myeloablative therapy followed by autologous hematopoietic stem cell (HSC) transplantation is a therapeutic option proposed for a variety of hematological and non-hematological diseases. However, although mortality due to this procedure is steadily decreasing, patients are still exposed to the risk of a number of complications negatively affecting ...
G, Lambertenghi Deliliers, C, Annaloro, D, Lambertenghi Deliliers   +2 more
openaire   +2 more sources

Autologous Hematopoietic Stem-Cell Transplantation for Multiple Myeloma

New England Journal of Medicine, 2009
A 59-year-old man is diagnosed with multiple myeloma. It is recommended that he receive induction therapy followed by high-dose melphalan with autologous hematopoietic stem-cell transplantation. Such transplantation improves the remission rate in myeloma by allowing for the administration of a chemotherapy dose that would otherwise be lethal.
Jean-Luc, Harousseau, Philippe, Moreau
openaire   +2 more sources

Application of autologous hematopoietic stem cell transplantation for pemphigus

International Journal of Dermatology, 2017
AbstractBackgroundPemphigus is a rare and fatal autoimmune disease for which the treatment options are limited. This study aimed to evaluate the efficacy of autologous peripheral hematopoietic stem cell transplantation (APHSCT) for pemphigus.MethodsWe conducted APHSCT for 12 pemphigus patients (seven males and five females, mean age 23.8 years) with ...
Menglei, Wang, Can, Cao, Jing, Sun, Xuebiao, Peng, Qifa, Liu, Liang, Huang, Yanyan, Chai, Kuan, Lai, Pingjiao, Chen, Qingxiu, Liu, Qian, Li, Yusheng, Peng, Hao, Xiong, Jing, Zhang, Minghua, Chen, Kang, Zeng   +15 more
openaire   +2 more sources