Results 121 to 130 of about 6,119,378 (259)

The long-term effect of AHSCT on MRI measures of MS evolution: a five-year follow-up study

, 2007
Using MRI, we measured disease activity and brain atrophy in nine multiple sclerosis patients treated with autologous hematopoietic stem cell transplantation (AHSCT) for a mean follow up of 63 months.
L. Bonzano, P Di Bartolomeo, G. Mancardi, C Iarlori, A Tartaro, M. Filippi, M. Rocca, Italian GITMO-NEURO Intergroup on Autologous Stem Cell Transplantation, P. Valsasina, M. Sormani, D Farina, R. Saccardi, L. Roccatagliata, A Lugaresi   +13 more
core  

Temporal trends in infectious risk among multiple myeloma patients treated with daratumumab: A meta‐analysis

British Journal of Haematology, EarlyView.
Summary Anti‐cluster of differentiation 38 (Anti‐CD38) monoclonal antibodies such as daratumumab are widely used in multiple myeloma (MM), yet the timing and magnitude of infectious risk remain incompletely defined. We performed an individual patient‐level meta‐analysis of six randomized trials (N = 2989) comparing daratumumab‐ versus non‐daratumumab ...
Alissa Visram, Hira Mian, James Lee, Aaron Jones, Gregory R. Pond, Doris Hansen, Surbhi Sidana, Luciano J. Costa   +7 more
wiley   +1 more source

Paediatric haematopoietic stem cell transplantation research priorities: Results from an international multi‐stakeholder priority setting partnership

British Journal of Haematology, EarlyView.
Summary Co‐designed research in paediatric HSCT is limited. We sought to determine research priorities which represent the shared priorities of patients, parents, carers and healthcare professionals (HCP) within Australia, New Zealand, the Netherlands and the United Kingdom.
Elizabeth Williams, Roxanne Dyas, Katherine Colman, Suzannah Kinsella, Amanda Gwee, Amy Lovell, Andrew R. Gennery, Mary Slatter, Lori Chait‐Rubinek, Eileen Van Der Stoep, Arjan Lankester, Hilda Mekelenkamp, Ben Gelbart, Karen Nicholson, Lorna McLeman, Shivanthan Shanthikumar, Vanessa Clifford, Theresa Cole, Gabrielle M. Haeusler, Lisa M. Ott de Bruin, Tim Prestidge, Adam Nelson, Kanchan Rao, Rachel Conyers, on behalf of the James Lind Alliance Priority Setting Partnership in Paediatric Haematopoietic Stem Cell Transplantation Steering Committee   +24 more
wiley   +1 more source

Real‐world outcomes of daratumumab, bortezomib, thalidomide and dexamethasone (Dara‐VTd) induction and lenalidomide maintenance in transplant‐eligible multiple myeloma

British Journal of Haematology, EarlyView.
Edvan Q. Crusoé, Glaciano Ribeiro, João Tadeu D. Souto Filho, Jayr Schmidt Filho, Natalia Schutz, Milton A. F. Aranha, Abel Costa, Abrahao Hallack, Fernando V. Pericole, Juliana S. Lima, Breno Gusmão, Eduardo Flávio O. Ribeiro, Jorge P. Vaz, Rosane Bittencourt, Rafael Cunha, Danielle Ovigli, Luiza Berg, Ederson R. Mattos, Angelo Maiolino, Vania Hungria, on behalf of GBRAM   +20 more
wiley   +1 more source

Whole‐genome and transcriptome analysis in relapsed/refractory non‐Hodgkin lymphoma: Results from a multicentre precision oncology cohort

British Journal of Haematology, EarlyView.
Summary Comprehensive genome and transcriptome profiling can inform the diagnosis, prognosis and management of relapsed/refractory (R/R) solid malignancies, yet its integration into clinical care has lagged despite strong biological rationale. We evaluated the clinical utility of whole genome and transcriptome analysis (WGTA) in 65 patients (37 ...
Kathleen Wee, Eric J. Zhao, Cassidy Clemente‐Jones, Rebecca J. Deyell, Shahrad R. Rassekh, Anita Villani, Rosemarie Venier, Daniel Sinnett, Sylvie Langlois, Thai Hoa Tran, Thomas Sontag, Stephanie Grover, Scott Davidson, Nisha Kanwar, Winnie Lo, Erin Pleasance, Laura Williamson, Yaoqing Shen, Alina S. Gerrie, Kerry J. Savage, Laurie H. Sehn, Christopher P. Venner, Marco A. Marra, Janessa Laskin, Diego Villa   +24 more
wiley   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

A prospective, phase IV study of ixazomib, pomalidomide and dexamethasone in patients with relapsed or refractory multiple myeloma

British Journal of Haematology, EarlyView.
Runfeng Zhang, Hong Yu, Miao Chen, Xiaoqi Qin, Jie Xiao, Yun Leng, Mingzhe Zhao, Jie Yu, Chunjie Qin, Xiuju Wang, Jingcheng Zhang, Wei Wang, Wenming Chen, Yanping Ma, Rong Fu, Junling Zhuang   +15 more
wiley   +1 more source

Evolution of CAR‐T Therapy: Functional Engineering, Manufacturing Innovation, and Future In Vivo Strategies

Cancer Science, EarlyView.
CAR‐T therapy is evolving across four interconnected dimensions: functional engineering, manufacturing innovation, alternative cell sources, and in vivo CAR programming. Together, these advances address limitations in therapeutic efficacy, safety, manufacturing complexity, scalability, and accessibility, providing complementary paths toward the next ...
Yukimi Sakoda
wiley   +1 more source

Autologous hematopoietic stem cell transplantation in Clarkson disease

The Journal of Allergy and Clinical Immunology: In Practice, 2023
Kirk M, Druey, A Robin, Eisch, Charlotte, Cunningham-Rundles   +2 more
openaire   +2 more sources

Cell separation and cryopreservation of cord blood fractions for immunotherapeutic applications [PDF]

, 2014
In 2008 Anthony Nolan opened the UK’s first public umbilical cord blood (CB) bank (Anthony Nolan Cell Therapy Centre, ANCTC) in which CB is stored for haematopoietic stem cell (HSC) transplantation. Due to strict quality thresholds, the majority of units
Fry, LJ
core