Results 31 to 40 of about 6,119,378 (259)

Epidemiology of Invasive Fungal Diseases: A 10-Year Experience in a Tertiary Pediatric Hematology–Oncology Department in Greece

Journal of Fungi
Although advances in the management of pediatric neoplasms have profoundly improved infectious disease outcomes, invasive fungal diseases (IFDs) remain a major cause of morbidity and mortality in children and adolescents with high-risk hematological ...
Eleni Moraitaki, Ioannis Kyriakidis, Iordanis Pelagiadis, Nikolaos Katzilakis, Maria Stratigaki, Georgios Chamilos, Athanasios Tragiannidis, Eftichia Stiakaki   +7 more
doaj   +1 more source

Mobilization with cyclophosphamide reduces the number of lymphocyte subpopulations in the leukapheresis product and delays their reconstitution after autologous hematopoietic stem cell transplantation in patients with multiple myeloma

Radiology and Oncology, 2016
Autologous hematopoietic stem cell transplantation is considered the standard of care for younger patients with multiple myeloma. Several mobilization regimens are currently used, most commonly growth factors alone or in combination with chemotherapy ...
Skerget Matevz, Skopec Barbara, Zontar Darja, Cernelc Peter   +3 more
doaj   +1 more source

Motixafortide and G-CSF to mobilize hematopoietic stem cells for autologous transplantation in multiple myeloma: A randomized phase 3 trial [PDF]

, 2023
Autologous hematopoietic stem cell transplantation (ASCT) improves survival in multiple myeloma (MM).
Vij, Ravi, et al.,, Crees, Zachary D, DiPersio, John F, Jayasinghe, Reyka G, Gao, Feng, Schroeder, Mark A, Rettig, Michael P, Stockerl-Goldstein, Keith, Schroeder, Mark A., DiPersio, John, García-Cadenas, Irene, Qazilbash, Muzaffar H, García Cadenas, Irene, Latif, Tahir, Gliko-Kabir, Irit, Illés, Árpád, Sorani, Ella, Hiemenz, John, DiPersio, John F., Milone, Giulio A, Sborov, Douglas, Mikala, Gabor, Martino, Massimo, Hardy, Nancy, Ickowicz, Debby, Rettig, Michael P., Moreno-Jiménez, Gemma, Holtick, Udo, Paciello Coronel, Maria Liz, Larson, Sarah M, Pereira, Denise, Goldstein, Inbal, Shemesh-Darvish, Liron, Arpad, Illes, Larson, Sarah M., Kadosh, Shaul, Micallef, Ivana, Jayasinghe, Reyka G., Stiff, Patrick, Crees, Zachary D., Qazilbash, Muzaffar H., Coronel, Maria Liz Paciello, Jayasinghe, Reyka, Vainstein-Haras, Abi, Milone, Giulio A., Universitat Autònoma de Barcelona   +46 more
core   +1 more source

Hematopoietic chimerism after allogeneic stem cell transplantation : a comparison of quantitative analysis by automated DNA sizing and fluorescent in situ hybridization [PDF]

, 2005
Background: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is performed mainly in patients with high-risk or advanced hematologic malignancies and congenital or acquired aplastic anemias.
Wachowiak, Jacek, Tomasz Strabel, Peter Bader, Bader, Peter, Jólkowska, Justyna, Jacek Wachowiak, Michał Witt, Anna Pieczonka, Strabel, Tomasz, Pieczonka, Anna, Dariusz Boruczkowski, Boruczkowski, Dariusz, Justyna Jółkowska, Witt, Michal   +13 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Myasthenia Gravis Treated With Autologous Hematopoietic Stem Cell Transplantation [PDF]

JAMA Neurology, 2016
Some patients with myasthenia gravis (MG) do not respond to conventional treatment and have severe or life-threatening symptoms. Alternate and emerging therapies have not yet proved consistently or durably effective. Autologous hematopoietic stem cell transplant (HSCT) has been effective in treating other severe autoimmune neurologic conditions and may
Adam, Bryant, Harold, Atkins, C Elizabeth, Pringle, David, Allan, Grizel, Anstee, Isabelle, Bence-Bruckler, Linda, Hamelin, Michael, Hodgins, Harry, Hopkins, Lothar, Huebsch, Sheryl, McDiarmid, Mitchell, Sabloff, Dawn, Sheppard, Jason, Tay, Christopher, Bredeson   +14 more
openaire   +2 more sources

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Autologous Hematopoietic Stem Cell Transplantation for Refractory Lupus Nephritis [PDF]

Clinical Journal of the American Society of Nephrology, 2019
Background and objectives Our study evaluated the efficiency and safety of autologous hematopoietic stem cell transplantation treatment for patients with refractory lupus nephritis. Design, setting, participants, & measurements From July 2011 to January 2015, a total of 22 ...
Xianghua Huang, Wencui Chen, Guisheng Ren, Liang Zhao, Jinzhou Guo, Dehua Gong, Caihong Zeng, Weixin Hu, Zhihong Liu   +8 more
openaire   +2 more sources

Association of DROSHA Variants with Susceptibility and Outcomes in Childhood Acute Lymphoblastic Leukemia

Current Issues in Molecular Biology
MicroRNAs are key regulators of lymphoid differentiation, exhibiting a pivotal role in acute lymphoblastic leukemia (ALL) biology and prognosis. The initial steps of canonical miRNA biogenesis involve the microprocessor complex processing the primary ...
Ioannis Kyriakidis, Iordanis Pelagiadis, Charalampos Pontikoglou, Helen A. Papadaki, Eftichia Stiakaki   +4 more
doaj   +1 more source

Autologous hematopoietic stem cell transplantation for autoimmune diseases: an observational study on 12 years’ experience from the European Group for Blood and Marrow Transplantation Working Party on Autoimmune Diseases

Haematologica, 2010
Background Autologous hematopoietic stem cell transplantation has been used since 1996 for the treatment of severe autoimmune diseases refractory to approved therapies.
Dominique Farge, Myriam Labopin, Alan Tyndall, Athanasios Fassas, Gian Luigi Mancardi, Jaap Van Laar, Jian Ouyang, Tomas Kozak, John Moore, Ina Kötter, Virginie Chesnel, Alberto Marmont, Alois Gratwohl, Riccardo Saccardi   +13 more
doaj   +1 more source