Results 11 to 20 of about 1,311 (180)

Autologous transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia achieves outcomes similar to allogeneic transplantation: results of CALGB Study 10001 (Alliance)

Haematologica, 2014
Allogeneic stem cell transplantation is the standard approach to Philadelphia chromosome positive acute lymphoblastic leukemia. We hypothesized that imatinib plus sequential chemotherapy will result in significant leukemia cell cytoreduction in patients ...
Meir Wetzler, Dorothy Watson, Wendy Stock, Gregory Koval, Flora A. Mulkey, Eva E. Hoke, John M. McCarty, William G. Blum, Bayard L. Powell, Guido Marcucci, Clara D. Bloomfield, Charles A. Linker, Richard A. Larson   +12 more
doaj   +1 more source

Approach to Macrodactyly: A Case Report and Diagnostic Algorithm for Syndromic and Isolated Forms

Pediatric Reports
Background: Macrodactyly (megalodactyly or digital gigantism) is a rare condition of overgrowth affecting one or more fingers or toes. Methods: We report a case of a 16-year-old Caucasian male with macrodactyly, lipomas, nevi, dysmorphic features, and ...
Ioannis Kyriakidis, Iordanis Pelagiadis, Nikolaos Katzilakis, Eftichia Stiakaki   +3 more
doaj   +1 more source

Upfront autologous stem cell transplantation for newly diagnosed elderly multiple myeloma patients: a prospective multicenter study

Haematologica, 2016
The feasibility and efficacy of high-dose melphalan followed by autologous hematopoietic stem cell transplantation in newly diagnosed elderly patients with multiple myeloma was analyzed prospectively. Fifty-six multiple myeloma patients, aged 65 years or
Laurent Garderet, Eric Beohou, Denis Caillot, Anne Marie Stoppa, Cyrille Touzeau, Marie Lorraine Chretien, Lionel Karlin, Philippe Moreau, Jean Fontan, Didier Blaise, Emmanuelle Polge, Mor Seny Gueye, Souhila Ikhlef, Zora Marjanovic, Myriam Labopin, Mohamad Mohty   +15 more
doaj   +1 more source

Autologous Hematopoietic Stem Cell Transplantation in the Treatment of Multiple Sclerosis [PDF]

Cold Spring Harbor Perspectives in Medicine, 2018
Multiple sclerosis (MS) is an autoimmune disorder that typically affects young people during their most productive years, causing irreversible damage and accumulation of disability. Treatments over time have had modest effects at completely controlling or suppressing disease activity, but are generally aimed at controlling early dominating inflammation
Carolina A, Rush, Harold L, Atkins, Mark S, Freedman   +2 more
openaire   +2 more sources

Epidemiology of Invasive Fungal Diseases: A 10-Year Experience in a Tertiary Pediatric Hematology–Oncology Department in Greece

Journal of Fungi
Although advances in the management of pediatric neoplasms have profoundly improved infectious disease outcomes, invasive fungal diseases (IFDs) remain a major cause of morbidity and mortality in children and adolescents with high-risk hematological ...
Eleni Moraitaki, Ioannis Kyriakidis, Iordanis Pelagiadis, Nikolaos Katzilakis, Maria Stratigaki, Georgios Chamilos, Athanasios Tragiannidis, Eftichia Stiakaki   +7 more
doaj   +1 more source

Mobilization with cyclophosphamide reduces the number of lymphocyte subpopulations in the leukapheresis product and delays their reconstitution after autologous hematopoietic stem cell transplantation in patients with multiple myeloma

Radiology and Oncology, 2016
Autologous hematopoietic stem cell transplantation is considered the standard of care for younger patients with multiple myeloma. Several mobilization regimens are currently used, most commonly growth factors alone or in combination with chemotherapy ...
Skerget Matevz, Skopec Barbara, Zontar Darja, Cernelc Peter   +3 more
doaj   +1 more source

Myasthenia Gravis Treated With Autologous Hematopoietic Stem Cell Transplantation [PDF]

JAMA Neurology, 2016
Some patients with myasthenia gravis (MG) do not respond to conventional treatment and have severe or life-threatening symptoms. Alternate and emerging therapies have not yet proved consistently or durably effective. Autologous hematopoietic stem cell transplant (HSCT) has been effective in treating other severe autoimmune neurologic conditions and may
Adam, Bryant, Harold, Atkins, C Elizabeth, Pringle, David, Allan, Grizel, Anstee, Isabelle, Bence-Bruckler, Linda, Hamelin, Michael, Hodgins, Harry, Hopkins, Lothar, Huebsch, Sheryl, McDiarmid, Mitchell, Sabloff, Dawn, Sheppard, Jason, Tay, Christopher, Bredeson   +14 more
openaire   +2 more sources

Tandem autologous hematopoietic stem cell transplantation for patients with multiple myeloma: a systematic review and meta-analysis

Hematology
To evaluate whether patients with multiple myeloma (MM) could benefit from tandem autologous hematopoietic stem cell transplantation (auto-HSCT), PubMed, Embase, Web of Science and Cochrane Library databases were systematically searched, and 10 eligible ...
Hongtao Li, Yaxin Zheng, Kehai Gao, Chen Tian   +3 more
doaj   +1 more source

Autologous Hematopoietic Stem Cell Transplantation for Refractory Lupus Nephritis [PDF]

Clinical Journal of the American Society of Nephrology, 2019
Background and objectives Our study evaluated the efficiency and safety of autologous hematopoietic stem cell transplantation treatment for patients with refractory lupus nephritis. Design, setting, participants, & measurements From July 2011 to January 2015, a total of 22 ...
Xianghua Huang, Wencui Chen, Guisheng Ren, Liang Zhao, Jinzhou Guo, Dehua Gong, Caihong Zeng, Weixin Hu, Zhihong Liu   +8 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source