Results 1 to 10 of about 1,242 (111)

Natural Killer Cells Are Key Host Immune Effector Cells Affecting Survival in Autologous Peripheral Blood Hematopoietic Stem Cell Transplantation

open access: yesCells, 2022
The infusion of autograft immune effector cells directly impacts the clinical outcomes of patients treated with autologous peripheral blood hematopoietic stem cell transplantation, suggesting the possibility of an autologous graft-versus tumor cells ...
Luis F. Porrata
doaj   +3 more sources

Optimizing Autologous Hematopoietic Stem Cell Transplantation for Acute Leukemia [PDF]

open access: yesStem Cells Translational Medicine, 2021
Abstract Autologous hematopoietic stem cell transplantation (ASCT) remains an important postremission treatment for acute leukemia (AL). It is known that some prognostic factors, such as age, cytogenetic and molecular risk stratification, and minimal residual disease (MRD) status, are closely related to clinical outcomes following ASCT ...
Aiming Pang   +2 more
exaly   +4 more sources

Autologous Hematopoietic Stem Cell Transplantation for Autoimmune Diseases [PDF]

open access: yesActa Haematologica, 2005
Ten years have passed since the first published consensus statement on the use of hematopoietic stem cell transplantation (HSCT) in the treatment of severe autoimmune disease (AD) appeared. During that time, around 700 patients suffering from severe AD have undergone HSCT in the frame of phase I/II clinical trials from over 20 countries including the ...
Tyndall A, Daikeler T
openaire   +8 more sources

Hospital and outpatient models for Hematopoietic Stem Cell Transplantation: A systematic review of comparative studies for health outcomes, experience of care and costs.

open access: yesPLoS ONE, 2021
The number of Hematopoietic Stem Cell Transplantations has risen in the past 20 years. The practice of outpatient Hematopoietic Stem Cell Transplantation programs is increasing in an attempt to improve the quality of patient care and reduce the demand ...
Marino J González   +10 more
doaj   +1 more source

Application of autologous hemopoietic stem cells in inoperable patients with chronic critical lower limb ischemia

open access: yesВестник хирургии имени И.И. Грекова, 2022
The OBJECTIVE was to study the efficiency of transplantation of autologous hematopoietic stem cells in patients with chronic critical lower limb ischemia and compare the results of treatment depending on the number of their transplantations.METHODS AND ...
I. P. Mikhaylov   +5 more
doaj   +1 more source

Autologous Graft-versus-Tumor Effect: Reality or Fiction?

open access: yesAdvances in Hematology, 2016
In contrast to allogeneic hematopoietic stem cell transplantation, the current dogma is not an evidence of graft-versus-tumor effect in autologous hematopoietic stem cell transplantation; thus, it is assumed that autologous hematopoietic stem cell ...
Luis F. Porrata
doaj   +1 more source

Endocrinopathies after Allogeneic and Autologous Transplantation of Hematopoietic Stem Cells [PDF]

open access: yesThe Scientific World Journal, 2014
Early and late endocrine disorders are among the most common complications in survivors after hematopoietic allogeneic- (allo-) and autologous- (auto-) stem cell transplant (HSCT). This review summarizes main endocrine disorders reported in literature and observed in our center as consequence of auto- and allo-HSCT and outlines current options for ...
Orio F   +9 more
openaire   +7 more sources

B–NHL Cases in a Tertiary Pediatric Hematology—Oncology Department: A 20-Year Retrospective Cohort Study

open access: yesLife
Non-Hodgkin lymphoma (NHL) is among the five most common pediatric cancer diagnoses in children and adolescents and consists of a heterogeneous group of lymphoid tissue malignancies –with B-cell-derived NHL accounting for nearly 80% of cases.
Ioannis Kyriakidis   +4 more
doaj   +1 more source

Functional Dominance of CHIP-Mutated Hematopoietic Stem Cells in Patients Undergoing Autologous Transplantation

open access: yesCell Reports, 2019
Summary: Clonal hematopoiesis of indeterminate potential (CHIP) is caused by recurrent somatic mutations leading to clonal blood cell expansion. However, direct evidence of the fitness of CHIP-mutated human hematopoietic stem cells (HSCs) in blood ...
Christina A. Ortmann   +20 more
doaj   +1 more source

Health-Related Quality of Life and Social Outcomes in Adolescents and Young Adult Survivors of Childhood Cancer: A Single-Center Case–Control Study from Crete, Greece

open access: yesReports
Background: Recent advances in childhood cancer treatment and increased survival rates have led to a growing number of adolescents and young adults (AYAs) who are survivors of childhood cancer (CCSs).
Ioannis Kyriakidis   +6 more
doaj   +1 more source

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