Results 91 to 100 of about 205,182 (367)

High-Dose Chemotherapy and Autologous or Allogeneic Transplantation in Aggressive B-Cell Lymphoma—Is There Still a Role?

Cells
Novel therapies such as CAR-T, BTK inhibitors and PD-1 inhibitors have changed the management of aggressive B-cell lymphomas. Nonetheless, these novel therapies have their own risk of late toxicities including second malignancies.
Michael Daunov, Koen van Besien
doaj   +1 more source

Extramedullary relapse of Immunoglobulin A-kappa myeloma manifesting as plasmacytoma of the pleura without bone marrow involvement and following autologous bone marrow transplant: a case report

Journal of Medical Case Reports, 2023
Background Recurrence of multiple myeloma is among the most challenging issues for patients and treating physicians reported after autologous stem cell transplantation.
Alireza Rezvani, Reza Shahriarirad, Mohammad Javad Fallahi, Ali Zeighami   +3 more
doaj   +1 more source

Whole Exome Sequencing to Estimate Alloreactivity Potential Between Donors and Recipients in Stem Cell Transplantation [PDF]

arXiv, 2014
Whole exome sequencing was performed on HLA-matched stem cell donors and transplant recipients to measure sequence variation contributing to minor histocompatibility antigen differences between the two. A large number of nonsynonymous single nucleotide polymorphisms were identified in each of the nine unique donor-recipient pairs tested. This variation
arxiv  

Autologous stem cell transplantation for systemic sclerosis

Autoimmunity, 2008
Systemic sclerosis (SSc) is a generalised autoimmune disease, of yet unknown origin, with two major clinical subsets: the limited (lcSSc) and the diffuse cutaneous (dcSSc) forms, which can be distinguished by the extent of skin involvement, the autoantibody profile and the pattern of organ involvement.
Dominique Farge, Richard Nash, Dominique Farge, Richard Nash, Jacob M. Laar, Dominique Farge, Richard Nash, Jacob M. Laar   +7 more
openaire   +3 more sources

Mycosis Fungoides, Sézary Syndrome, and Cutaneous B‐Cell Lymphomas: 2025 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Disease Overview Primary cutaneous lymphomas are a rare and heterogeneous group of extranodal lymphomas that require the integration of clinical and histopathologic data for classification and treatment. Diagnosis Diagnosis and disease classification is based on histopathologic review and immunohistochemical staining of an appropriate skin ...
Alexandra C. Hristov, Trilokraj Tejasvi, Ryan A. Wilcox   +2 more
wiley   +1 more source

Upfront autologous stem cell transplantation for newly diagnosed elderly multiple myeloma patients: a prospective multicenter study

Haematologica, 2016
The feasibility and efficacy of high-dose melphalan followed by autologous hematopoietic stem cell transplantation in newly diagnosed elderly patients with multiple myeloma was analyzed prospectively. Fifty-six multiple myeloma patients, aged 65 years or
Laurent Garderet, Eric Beohou, Denis Caillot, Anne Marie Stoppa, Cyrille Touzeau, Marie Lorraine Chretien, Lionel Karlin, Philippe Moreau, Jean Fontan, Didier Blaise, Emmanuelle Polge, Mor Seny Gueye, Souhila Ikhlef, Zora Marjanovic, Myriam Labopin, Mohamad Mohty   +15 more
doaj   +1 more source

A case report: high dose melphalan as a conditioning regimen for multiple myeloma induces sinus arrest

Cardio-Oncology, 2020
High dose melphalan is commonly used as a conditioning regimen for autologous stem cell transplantation in multiple myeloma. There are reports of adverse cardiac events with melphalan manifested by supraventricular tachycardia and atrial fibrillation ...
Liang-Liang Ma, Ying Liu, Si-Xun Jia, Hai-Chen Lv, Mei-Yun Fang, Yun-Long Xia   +5 more
doaj   +1 more source

Autologous hematopoietic stem cell transplantation for autoimmune diseases [PDF]

Bone Marrow Transplantation, 2005
Experimental data and early phase I/II studies suggest that high-dose chemotherapy followed by autologous hematopoietic stem cell transplantation (HSCT) can arrest progression of severe autoimmune diseases. We have evaluated the toxicity and disease response in 473 patients with severe autoimmune disease treated with autologous HSCT between 1995 and ...
Gratwohl, Alois, Passweg, Jakob, Bocelli-Tyndall, Chiara, Fassas, Athanasios, Laar, Jacob M. van, Farge, Dominique, Andolina, Marino, Arnold, Raoul, Carreras, Edward, Finke, Jürgen, Kötter, Ina, Kozak, Tomas, Lisukov, Igor A., Löwenberg, Bob, Marmont, Alberto, Moore, Joseph O., Saccardi, Riccardo, Snowden, John A., Hoogen, Frank H. J. van den, Wulffraat, Nico Martinus, Zhao, Xiaowu, Tyndall, Alan   +21 more
openaire   +5 more sources

Risk for Clostridium difficile infection after allogeneic hematopoietic cell transplant remains elevated in the postengraftment period [PDF]

, 2017
BACKGROUND: Clostridium difficile infection (CDI) is a frequent cause of diarrhea among allogeneic hematopoietic cell transplant (HCT) recipients. It is unknown whether risk factors for CDI vary by time posttransplant.
Bommarito, Kerry M, Chiller, Tom M, DiPersio, John, Dubberke, Erik R, Fraser, Victoria J, Olsen, Margaret A, Reske, Kimberly A, Seiler, Sondra, Silveira, Fernanda P   +8 more
core   +2 more sources

Advances in CRISPR‐Cas9 in lineage tracing of model animals

Animal Models and Experimental Medicine, EarlyView.
Cell lineage tracing is a key technology for describing the developmental history of individual progenitor cells and assembling them to form a lineage development tree. However, traditional methods have limitations of poor stability and insufficient resolution.
Jingchao Cao, Zihang Guo, Xueling Xu, Pan Li, Yi Fang, Shoulong Deng   +5 more
wiley   +1 more source