Results 111 to 120 of about 154,826 (359)

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

Safety and feasibility of Lin- cells administration to ALS patients : a novel view on humoral factors and miRNA profiles [PDF]

, 2018
Therapeutic options for amyotrophic lateral sclerosis (ALS) are still limited. Great hopes, however, are placed in growth factors that show neuroprotective abilities (e.g., nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and vascular
Baumert, Bartłomiej, Dulak, Józef, Gołąb-Janowska, Monika, Gródecka-Szwajkiewicz, Dorota, Kawa, Miłosz P., Kotowski, Maciej, Litwińska, Zofia, Machaliński, Bogusław, Nowacki, Przemysław, Peregud-Pogorzelski, Jarosław, Pius-Sadowska, Ewa, Sobuś, Anna, Stępniewski, Jacek   +12 more
core   +2 more sources

Graft-versus-host disease in a child with neuroblastoma after autologous stem cell transplantation

Contemporary Oncology, 2019
In the pediatric population, hematopoietic stem cell transplantation (HSCT) is used to treat a wide variety of diseases, both malignant and nonmalignant. For many of these diseases, HSCT is a well-established treatment.
Yöntem Yaman, Gökhan Baysoy, Emre Keleşoğlu, Kürşat Özdilli, Aslı Çakır, Dildar Bahar Genç, Murat Elli, Sema Anak   +7 more
doaj   +1 more source

Elevator‐Like Hollow Channels in Porous Scaffolds Accelerate Vascularized Bone Regeneration via NETs‐Fibrin‐Mediated Macrophage Recruitment

Advanced Science, EarlyView.
This study demonstrates that how hollow‐channel scaffolds promote vascularized bone regeneration via an immunomodulatory mechanism. The channel structures facilitate the formation of a neutrophil extracellular traps‐fibrin scaffold that recruits vascular endothelial growth factor A (VEGF‐A)‐secreting M2 macrophages to drive angiogenesis. Combining this
Guifang Wang, Rongpu Liu, Huijing Ma, Shuhan Duan, Guangzheng Yang, LingXi Meng, Yuqin Qiao, Dongqiang Song, Wenjie Zhang   +8 more
wiley   +1 more source

Generation of Oligodendrocyte Progenitor Cells From Mouse Bone Marrow Cells. [PDF]

, 2019
Oligodendrocyte progenitor cells (OPCs) are a subtype of glial cells responsible for myelin regeneration. Oligodendrocytes (OLGs) originate from OPCs and are the myelinating cells in the central nervous system (CNS).
Casella, Giacomo, Han, Juan-Juan, Jia, Ling-Yu, Li, Xing, Lu, Xin-Yu, Rostami, A. M., Tian, Jing, Yang, Ting, Ye, Ze-Qing, Zhang, Yuan   +9 more
core   +1 more source

Fatal CMV-Infection after Autologous Stem Cell Transplantation in Refractory Systemic Lupus Erythematosus

Case Reports in Transplantation, 2012
High-dose chemotherapy followed by autologous stem cell transplantation can be a rescue for patients with severe refractory systemic lupus erythematosus (SLE). However, the procedure might have fatal complications including infections and bleeding.
László Váróczy, Emese Kiss, Tünde Tarr, Margit Zeher, Gyula Szegedi, Árpád Illés   +5 more
doaj   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

A Phase I Dose-Escalation Trial of High-Dose Melphalan with Palifermin for Cytoprotection Followed by Autologous Stem Cell Transplantation for Patients with Multiple Myeloma with Normal Renal Function [PDF]

, 2012
Muneer H. Abidi, Rishi Agarwal, Nishant Tageja, Lois Ayash, Abhinav Deol, Zaid Al‐Kadhimi, Judith Abrams, Simon Cronin, Marie Ventimiglia, Lawrence G. Lum, Voravit Ratanatharathorn, Jeffrey A. Zonder, Joseph P. Uberti   +12 more
openalex   +1 more source

Perturbation of the gut microbiome and association with outcomes following autologous stem cell transplantation in patients with multiple myeloma

, 2022
Christopher R. D’Angelo, Sailendharan Sudakaran, Fotis Asimakopoulos, Peiman Hematti, Dalia El‐Gamal, Nasia Safdar, Natalie S. Callander   +6 more
openalex   +2 more sources

Autologous stem cell transplantation for systemic sclerosis

Autoimmunity, 2008
Systemic sclerosis (SSc) is a generalised autoimmune disease, of yet unknown origin, with two major clinical subsets: the limited (lcSSc) and the diffuse cutaneous (dcSSc) forms, which can be distinguished by the extent of skin involvement, the autoantibody profile and the pattern of organ involvement.
Dominique Farge, Richard Nash, Dominique Farge, Richard Nash, Jacob M. Laar, Dominique Farge, Richard Nash, Jacob M. Laar   +7 more
openaire   +3 more sources