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Autologous Stem Cell Transplantation in Lymphoma
Seminars in Hematology, 2007High-dose therapy (HDT) followed by autologous transplantation of hematopoietic stem cells (ASCT) is frequently performed in patients with lymphoma. For many subentities, reliable results from prospective randomized studies are missing. In Hodgkin's disease (HD), HDT/ASCT is a standard indication for patients with chemosensitive first relapse. Patients
Christian Gisselbrecht +2 more
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Autologous Stem Cell Transplantation in Myelodysplastic Syndromes
Seminars in Hematology, 2007Allogeneic stem cell transplantation (SCT) is the treatment of choice for the majority of young patients with myelodysplasia (MDS) who have a histocompatible donor (sibling or unrelated donor). For some patients lacking a human leukocyte antigen (HLA)-compatible donor, chemotherapy followed by autologous SCT may be a reasonable alternative, especially ...
Witte, T.J.M. de +4 more
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Autologous stem cell transplantation in multiple myeloma
Panminerva Medica, 2021The treatment of patients with multiple myeloma has changed in the last decades, with an improved median survival of 8-10 years. The current treatment for newly diagnosed multiple myeloma patients eligible for autologous transplantation consists of 4 phases: pretransplant, induction, transplant, post-transplant consolidation and maintenance. Even today,
Giovanni Martinelli +4 more
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Autologous Stem Cell Transplantation
2016Autologous stem cell transplantation (ASCT) is a treatment strategy that allows for the administration of higher than usual doses of myelotoxic chemotherapy and/or radiation therapy to treat several hematologic and nonhematologic malignancies. High-dose chemotherapy (HDT) with ASCT is widely performed in HIV-negative patients with Hodgkin (HL) and non ...
Alessandro Re +2 more
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Autologous stem cell transplantation and IgM amyloidosis
Leukemia & Lymphoma, 2006High dose chemotherapy (HDC) followed by autologous stem cell transplant (ASCT) is an accepted form of treatment for patients with AL amyloidosis. The purpose of the current study is to review the outcomes of IgM AL amyloidosis patients treated with high dose chemotherapy and autologous stem cell transplant and compare them to the outcomes of all AL ...
Angela Dispenzieri +4 more
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Autologous Stem Cell Transplantation in Autoimmune Diseases
Seminars in Hematology, 2007Since 1996, approximately 1,000 patients have received an autologous hematopoietic stem cell transplant (HSCT) as treatment for a severe autoimmune disease (AD). The European Group for Blood and Marrow Transplantation (EBMT)/European League Against Rheumatism (EULAR) Autoimmune Disease Working Party have registered more than 800 patients and works in ...
Alan Tyndall, Jakob Passweg
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Rationale for Purging in Autologous Stem Cell Transplantation
Journal of Hematotherapy, 1993The success of autologous stem cell transplantation using bone marrow or peripheral blood stem cells depends not only on in vivo irradication of the disease by cytotoxic therapy but also on complete hematopoietic engraftment with no risk of relapse from the infused cells. Various methods are available for removing (purging) such contaminants.
Luis Acaba, Subhash C. Gulati
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Autologous hematopoietic stem cells transplantation in MOGAD
Multiple Sclerosis Journal[no abstract available]
Mariotto, Sara, Carta, Sara
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Autologous stem cell transplantation for myocardial repair
American Journal of Physiology-Heart and Circulatory Physiology, 2004Current therapies for heart failure due to transmural left ventricular (LV) infarction are limited. We have developed a novel patch method for delivering autologous bone marrow stem cells to sites of myocardial infarction for the purpose of improving LV function and preventing LV aneurysm formation.
Robert J. Bache +14 more
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Complications of autologous hematopoietic stem cell transplantation
Haematologia, 2000Myeloablative therapy followed by autologous hematopoietic stem cell (HSC) transplantation is a therapeutic option proposed for a variety of hematological and non-hematological diseases. However, although mortality due to this procedure is steadily decreasing, patients are still exposed to the risk of a number of complications negatively affecting ...
Claudio Annaloro +2 more
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