Results 81 to 90 of about 205,182 (367)

Sowing the Seeds of a Fruitful Harvest: Hematopoietic Stem Cell Mobilization [PDF]

, 2013
Hematopoietic stem cell transplantation is the only curative option for a number of malignant and non-malignant diseases. As the use of hematopoietic transplant has expanded, so too has the source of stem and progenitor cells.
Hoggatt, Jonathan, Pelus, Louis M., Speth, Jennifer M.   +2 more
core   +1 more source

Bionic Nanostructures Create Mechanical Signals to Mediate the Composite Structural Bone Regeneration Through Multi‐System Regulation

Advanced Science, EarlyView.
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei, Yihan Wang, Jingxia Chen, Jing Zhou, Yuzhu Han, Xiuyu Liu, Siyu Chen, Sheng Chen, Dixin He, Yunxiao Wu, Huixin Lv, Yanmin Zhou   +11 more
wiley   +1 more source

A Comparison of Allogeneic and Autologous Hematopoietic Stem Cell Transplantation for Acute Myeloblastic Leukemia [PDF]

International Journal of Hematology-Oncology and Stem Cell Research, 2009
Introduction: Acute Myelogenous Leukemia (AML) is a clonal  malignant disease of hematopoietic tissue. The early use of  Hematopoietic Stem Cell Transplantation (HSCT) for AML was for patients with advanced stages of disease, usually while in relapse, in
Ardeshir Ghavamzadeh, Atefeh Masnavi, Farnaz Khatami, Arash Jalali, Kamran Alimoghaddam   +4 more
doaj   +1 more source

Mobilization with cyclophosphamide reduces the number of lymphocyte subpopulations in the leukapheresis product and delays their reconstitution after autologous hematopoietic stem cell transplantation in patients with multiple myeloma

Radiology and Oncology, 2016
Autologous hematopoietic stem cell transplantation is considered the standard of care for younger patients with multiple myeloma. Several mobilization regimens are currently used, most commonly growth factors alone or in combination with chemotherapy ...
Skerget Matevz, Skopec Barbara, Zontar Darja, Cernelc Peter   +3 more
doaj   +1 more source

Dynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides Demonstrates Different Alloreactivity Potential In HLA-Matched and Mismatched Donor-Recipient Pairs [PDF]

arXiv, 2015
Stem cell transplants may be considered as dynamical systems to allow sequence differences across the exomes of the transplant donors and recipients to be used to simulate an alloreactive T cell response. Whole exome sequencing was performed on HLA matched stem cell transplant donor-recipient pairs, and the nucleotide sequence differences translated to
arxiv  

Separable pathway effects of semi-competing risks using multi-state models [PDF]

arXiv, 2023
Semi-competing risks refer to the phenomenon where a primary event (such as mortality) can ``censor'' an intermediate event (such as relapse of a disease), but not vice versa. Under the multi-state model, the primary event consists of two specific types: the direct outcome event and an indirect outcome event developed from intermediate events.
arxiv  

Autologous stem cell transplantation in Hodgkin's disease

Annals of Oncology, 2002
The majority of patients with Hodgkin’s disease (HD) are curable with first-line therapy; however, 10–20% of patients with advanced HD will not enter complete remission (CR) with conventional first-line therapy and a further 20–30% will relapse after having initially achieved CR [1–3].
I. Avivi, A. H. Goldstone
openaire   +3 more sources

Polyomavirus Nephropathy in Autologous Stem Cell Transplantation [PDF]

Kidney International Reports, 2018
BK virus was first detected in the urine of a renal transplant recipient in 1971 and was named after the recipient.1 BK virus is usually acquired in childhood2 via respiratory transmission, and remains in the uroepithelium of immunocompetent individuals.3 The seroprevalence in adults is 82% to 99%,4 with low-level viruria seen in 5% to 20% of ...
Shahid Husain, Rohan John, Clarissa A. Cassol, Tushar S Malavade, Christopher T. Chan, Christine Chen   +5 more
openaire   +2 more sources

A proof-of-concept clinical trial using mesenchymal stem cells for the treatment of corneal epithelial stem cell deficiency [PDF]

, 2019
Producción CientíficaOcular stem cell transplantation derived from either autologous or allogeneic donor corneoscleral junction is a functional cell therapy to manage extensive and/or severe limbal stem cell deficiencies that lead to corneal epithelial ...
Alberca Zaballos, Mercedes, Calonge Cano, Margarita, Fernández Martínez, Itziar, Galindo de la Rosa, Sara, García-Sancho Martín, Francisco Javier, Herreras Cantalapiedra, José María, López Paniagua, Marina, Nieto Miguel, Teresa, Pérez Soto, María Inmaculada, Sánchez García, Ana María de los Ángeles   +9 more
core   +2 more sources

Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications

Advanced Intelligent Systems, EarlyView.
Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu, Amar Salehi, Lei Xu, Wei Yuan, Tingting Yu   +4 more
wiley   +1 more source