Results 81 to 90 of about 194,426 (295)
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Carton, Olivier, Michel, Max
openaire +3 more sources
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Minimal weight expansions in Pisot bases
For applications to cryptography, it is important to represent numbers with a small number of non-zero digits (Hamming weight) or with small absolute sum of digits.
Frougny Christiane, Steiner Wolfgang
doaj +1 more source
The framework of Hybrid automata, introduced by Alur, Courcourbetis, Henzinger, and Ho, provides a formal modeling and analysis environment to analyze the interaction between the discrete and the continuous parts of cyber-physical systems.
A.P. Sistla +9 more
core +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Hypercompositional Algebra, Computer Science and Geometry
The various branches of Mathematics are not separated between themselves. On the contrary, they interact and extend into each other’s sometimes seemingly different and unrelated areas and help them advance. In this sense, the Hypercompositional Algebra’s
Gerasimos Massouros, Christos Massouros
doaj +1 more source
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Digital Semantics for Enterprise Information System Development
This position paper discusses the use of Digital Semantics, ontologies, and automata in the era of Artificial Intelligence (AI). Digital Semantics represents a potential new definition and paradigm for simulating human intelligence within a machine ...
Gaetanino Paolone +2 more
doaj +1 more source

