Results 81 to 90 of about 194,426 (295)

Unambiguous Büchi Automata

open access: yesTheoretical Computer Science, 2000
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Carton, Olivier, Michel, Max
openaire   +3 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Minimal weight expansions in Pisot bases

open access: yesJournal of Mathematical Cryptology, 2008
For applications to cryptography, it is important to represent numbers with a small number of non-zero digits (Hamming weight) or with small absolute sum of digits.
Frougny Christiane, Steiner Wolfgang
doaj   +1 more source

Weak Singular Hybrid Automata

open access: yes, 2014
The framework of Hybrid automata, introduced by Alur, Courcourbetis, Henzinger, and Ho, provides a formal modeling and analysis environment to analyze the interaction between the discrete and the continuous parts of cyber-physical systems.
A.P. Sistla   +9 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Hypercompositional Algebra, Computer Science and Geometry

open access: yesMathematics, 2020
The various branches of Mathematics are not separated between themselves. On the contrary, they interact and extend into each other’s sometimes seemingly different and unrelated areas and help them advance. In this sense, the Hypercompositional Algebra’s
Gerasimos Massouros, Christos Massouros
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Digital Semantics for Enterprise Information System Development

open access: yesEngineering Proceedings
This position paper discusses the use of Digital Semantics, ontologies, and automata in the era of Artificial Intelligence (AI). Digital Semantics represents a potential new definition and paradigm for simulating human intelligence within a machine ...
Gaetanino Paolone   +2 more
doaj   +1 more source

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