Results 61 to 70 of about 3,225 (296)
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Faster cellular automata cryptosystems with neighbor sequences [PDF]
, 2023 The encryption processes and cryptosystems are very important. We use them to protect our private information over the Internet. Cellular automata are ones of the computational models that can also be used in cryptosystems.
Athasit Surarerks, Kittiphop Phalakarn
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Testing from a nondeterministic finite state machine using adaptive state counting [PDF]
, 2004 The problem of generating a checking experiment from a nondeterministic finite state machine has been represented in terms of state counting. However, test techniques that use state counting traditionally produce preset test suites.
Hierons, RM
core +1 more source
RNA-Editing with Combined Insertion and Deletion Preserves Regularity [PDF]
Scientific Annals of Computer Science, 2013 We consider two elementary forms of string rewriting called guided insertion/deletion and guided rewriting. The original strings are modified depending on the match with a given set of auxiliary strings, called guides. Guided insertion/deletion considers
E.P. de Vink, H. Zantema, D. Bošnački
doaj +1 more source
Random Sequence Generation by Cellular Automata
Advances in Applied Mathematics, 1986 A 1-dimensional cellular automaton which generates random sequences is discussed. Each site in the cellular automaton has value 0 or 1, and is updated in parallel according to the rule \[ a_ i'=a_{i-1} XOR (a_ i OR a_{i+1})(a_ i'=(a_{i-1}+a_ i+a_{i+1}+a_ ia_{i+1}) mod 2). \] Despite the simplicity of this rule, the time sequences of site values that it
openaire +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source