Results 51 to 60 of about 3,447,572 (320)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Frontiers in Rehabilitation SciencesIntroductionUltrasound is a cost-effective and reliable method to determine skeletal muscle architecture. However, manual analysis of fascicle length (FL) and pennation angle (PA) can be arduous and subjective among raters, particularly among novice ...
Micheal J. Luera +13 more
doaj +1 more source
AUTOMATION AND GAMIFICATION OF COMPUTER SCIENCE STUDY
Studia Universitatis Babes-Bolyai: Series Informatica, 2019 A large part of the job of a university teacher in computer science is to verify student exercises. The task of verifying correctness, coding style, conventions, and grading is laborious and if done correctly leaves little time for questions. Automating
Imre ZSIGMOND
doaj +1 more source
Assigned responsibility for remote robot operation [PDF]
, 2015 The remote control of robots, known as teleoperation, is a non-trivial task, requiring the operator to make decisions based on the information relayed by the robot about its own status as well as its surroundings.
Lee, K, Mann, G, Small, NJ
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Chengshi guidao jiaotong yanjiu[Objective] Digital twin technology is the booster for many industries to embark on the path of intelligence, information, and digitalization. To promote the digital development of urban rail transit vehicle bases, a fully automated depot train ...
Kai FENG, Hui ZHENG
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
A Layered Middleware Architecture for Automated Robot Services
International Journal of Distributed Sensor Networks, 2014 These days, using robots has gradually been extending from the limited industrial areas in factories to service areas for the general public in everyday life.
Jongsun Choi +3 more
doaj +1 more source