Results 101 to 110 of about 533,809 (303)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Algorithm of the automated control of displacement of the load overall center of gravity of railroad car for railway transportation

Вестник Научно-исследовательского института железнодорожного транспорта, 2019
The algorithm is proposed for the automated control of displacement of the load overall center of gravity relative to transversal and/or longitudinal planes of symmetry of the car during railway transportation and decision-making about availability of ...
Tat’yana A. Vinokurova, Andrey B. Galushkin, Anatoliy A. Rakhmilevich   +2 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Design of A Catfish Seed Sorting Machine with Calculation of Quantity and Selling Price

Jurnal Jaringan Telekomunikasi
This research addresses the inefficiencies in manual catfish sorting and sales data management encountered by small-scale farmers. The study designs and implements an automated sorting machine integrated with a quantity counting and sales price ...
Arfin Ardiansyah Arfin, Hadiwiyatno Hadiwiyatno, Aad Hariyadi   +2 more
doaj   +1 more source

DETERMINATION OF DESIGN PARAMETERS OF ARTICULATED JIB SYSTEMS OF PORTAL CRANE

Nauka ta progres transportu, 2017
Purpose. The study involves: 1) formation of an array of geometry, weight and variable data for the automated synthesis of articulated jib systems; 2) development of methodology of calculation and determination of rational design parameters of the ...
V. V. Suglobov, K. V. Tkachuk
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

A Knowledge Graph-Based Method for Calculating Limits of Transmission Sections

IEEE Access
The secure operation of large-scale power systems relies on adherence to pre-established section limits. However, the calculation of section limits is dependent heavily on expert experience, leading to significant individual variability and subjectivity ...
Linbo Fang, Weilong Tao, Chenggong Cao, Zejian Hu, Kun Liang   +4 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

NNLO predictions for Z-boson pair production at the LHC

, 2018
We present a calculation of the NNLO QCD corrections to Z-boson pair production at hadron colliders, based on the N-jettiness method for the real radiation parts.
Heinrich, G., Jahn, S., Jones, S. P., Kerner, M., Pires, Joao   +4 more
core   +1 more source