Results 41 to 50 of about 15,504 (307)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Optimization of Resource Allocation in Automated Container Terminals

Sustainability, 2022
Automated container terminals have been constructed to reduce emissions and labor cost. Resource allocation problems in automated container terminals have a critical effect on handling efficiency and cost. This paper addresses this problem with quay crane (QC) double cycling in automated container terminals. An optimization model is developed to obtain
Xiaoju Zhang, Huijuan Li, Meng Wu
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Improvement of Container Dynamic Allocation for Automated Container Terminals in the Post-Epidemic Era

Journal of Marine Science and Engineering
The significant congestion during the COVID-19 epidemic has prompted terminal managers to prioritize efforts to enhance daily operational efficiency in the post-epidemic era.
Yu Wang, Junliang He, Leijie Zhang, Wei Yan   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Automated Guided Vehicle (AGV) Scheduling in Automated Container Terminals (ACTs) Focusing on Battery Swapping and Speed Control

Journal of Marine Science and Engineering, 2023
Because they are environmentally friendly and safe, automated guided vehicles (AGVs) are increasingly used in newly constructed automated container terminals. However, their scheduling strategy is constrained by their limited battery capacity.
Xurui Yang, Hongtao Hu, Chen Cheng, Yuren Wang   +3 more
doaj   +1 more source

Stakeholders’ attitudes toward container terminal automation

Maritime Economics & Logistics
Abstract This study examines stakeholders' attitudes toward container terminal automation, aiming to place terminal automation as an innovation trajectory in the broader context of stakeholder relations management. Detailing first how the stakeholder environment plays a crucial role in shaping the path toward adopting innovation, the ...
Notteboom, Theo, Pallis, Athanasios A., Knatz, Geraldine   +2 more
openaire   +2 more sources

The impact of innovation on dock labour : evidence from European ports [PDF]

, 2019
The market environment of ports and terminals is continuously pushing terminal operators to achieve higher levels of dock labour performance. This paper proposes an original conceptual framework to identify, classify and evaluate innovative initiatives ...
Notteboom, Theo, Vitellaro, Fracesco
core   +1 more source