Results 41 to 50 of about 15,544 (306)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Study on Distributed Consistent Cooperative Control of Multi-ART in Automated Container Terminals

IEEE Access, 2022
In order to address the congestion problem of vehicles in quay of automated container terminal with parallel layout and side-loading operations, the study regards the terminal operation system as a multi-agent system (MAS).
Yu Zhang, Caiyun Yang, Kexin Tang, Jinshan Dai   +3 more
doaj   +1 more source

Optimization of Resource Allocation in Automated Container Terminals

Sustainability, 2022
Automated container terminals have been constructed to reduce emissions and labor cost. Resource allocation problems in automated container terminals have a critical effect on handling efficiency and cost. This paper addresses this problem with quay crane (QC) double cycling in automated container terminals. An optimization model is developed to obtain
Xiaoju Zhang, Huijuan Li, Meng Wu
openaire   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Double-Cycling AGV Scheduling Considering Uncertain Crane Operational Time at Container Terminals

Applied Sciences, 2022
Container terminals (CTs) play an important role in the modern logistics and transportation industry. The utilization of automated guided vehicles (AGVs) can be effectively facilitated by reducing their empty running.
Hongchang Zhang, Liang Qi, Wenjing Luan, Huijuan Ma   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Improvement of Container Dynamic Allocation for Automated Container Terminals in the Post-Epidemic Era

Journal of Marine Science and Engineering
The significant congestion during the COVID-19 epidemic has prompted terminal managers to prioritize efforts to enhance daily operational efficiency in the post-epidemic era.
Yu Wang, Junliang He, Leijie Zhang, Wei Yan   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Stakeholders’ attitudes toward container terminal automation

Maritime Economics & Logistics
Abstract This study examines stakeholders' attitudes toward container terminal automation, aiming to place terminal automation as an innovation trajectory in the broader context of stakeholder relations management. Detailing first how the stakeholder environment plays a crucial role in shaping the path toward adopting innovation, the ...
Notteboom, Theo, Pallis, Athanasios A., Knatz, Geraldine   +2 more
openaire   +2 more sources