Results 221 to 230 of about 94,190 (294)

Preclinical signal for a disease‐modifying effect on seizure cluster severity with intermittent diazepam treatment

Epilepsia, EarlyView.
Abstract Objective In epilepsy, daily treatment provides only symptomatic seizure control, leaving a significant unmet need for a treatment that affects the underlying predisposition to seizures. Here, in a first‐of‐its‐kind study, we test the hypothesis that intermittent treatment of seizure clusters with diazepam in the kainic acid post‐status ...
Qian Wu, Michelle Guignet, Jonathan Vuong, H. Steve White, Wesley T. Kerr, Evelyn K. Shih, Leock Y. Ngo, Enrique Carrazana, Adrian L. Rabinowicz   +8 more
wiley   +1 more source

High-Throughput 3D Glioblastoma Model in Glycosaminoglycan Hydrogels for Personalized Therapeutic Screening. [PDF]

Macromol Biosci
Trautmann RK, Dennison N, McCortney K, Klier S, Cosacak MI, Werner C, Akyoldas G, Horbinski CM, Freudenberg U, Kizil C.   +9 more
europepmc   +1 more source

Targeting Hsp90 with cemdomespib reduces seizure burden and alters disease course in preclinical epilepsy models

Epilepsia, EarlyView.
Abstract Objective Epilepsy is a chronic neurological disorder characterized by recurrent seizures and frequent cognitive and psychiatric comorbidities. Although current antiseizure medications provide symptomatic relief, they fail to prevent or modify epileptogenesis.
Yara Sheeni, Prince Kumar Singh, Sereen Sandouka, Taige Zhang, Alina Nemirovski, Aseel Saadi, Rhoda Olowe Taiwo, Matthew C. Walker, Tawfeeq Shekh‐Ahmad   +8 more
wiley   +1 more source

Top-Down Design Approach of Lightweight Composite Battery Pack Enclosure for Electric Vehicles Based on Numerical Modeling and Topology Optimization. [PDF]

Polymers (Basel)
Zhang X, Lin Q, Xiao Y, Jia L, Yang T, Wang L, Ma Q, Wang B.   +7 more
europepmc   +1 more source

AI‐based localization of the epileptogenic zone using intracranial EEG

Epilepsia Open, EarlyView.
Abstract Artificial intelligence (AI) is rapidly transforming our lives. Machine learning (ML) enables computers to learn from data and make decisions without explicit instructions. Deep learning (DL), a subset of ML, uses multiple layers of neural networks to recognize complex patterns in large datasets through end‐to‐end learning.
Atsuro Daida, Yipeng Zhang, Sotaro Kanai, Richard Staba, Vwani Roychowdhury, Hiroki Nariai   +5 more
wiley   +1 more source

ICP-Based Mapping and Localization System for AGV with 2D LiDAR. [PDF]

Sensors (Basel)
Silva FL, Fernandes EM, Barros PR, Pimentel LDC, Pimenta FC, Lima AGB, Delgado JMPQ.   +6 more
europepmc   +1 more source

Decentralized Wind Energy Systems as Catalysts for Urban Resilience: A Design Framework

Energy Science &Engineering, EarlyView.
ABSTRACT Confronting the escalating extreme weather events (EWEs) and intensifying winds, this study proposes an active response to these issues by exploring decentralized wind energy production for Peng Chau Island, Hong Kong. It integrates theoretical perspectives on energy democracy—empowering local communities through energy autonomy—and urban ...
Tian Cheng
wiley   +1 more source

Passive wheels - A new localization system for automated guided vehicles. [PDF]

Heliyon
Bereszyński K, Pelic M, Paszkowiak W, Pabiszczak S, Myszkowski A, Walas K, Czechmanowski G, Węgrzynowski J, Bartkowiak T.   +8 more
europepmc   +1 more source

Hydrogen Fuel Cell Technologies for Decarbonization: Opportunities, Challenges, and Strategic Pathways—A Comprehensive Review

Energy Science &Engineering, EarlyView.
ABSTRACT Hydrogen (H2) fuel cells are increasingly recognized as a cornerstone technology in the global transition toward clean energy due to their high efficiency and zero‐emission characteristics. This review synthesizes recent progress, challenges, and strategic pathways for the deployment of H2 fuel cells across the transportation, power generation,
Yash Sachin Gupta, Aarav Sachin Gupta, Rajkumar Sivanraju, K. R. Padmavathi, Ashok Kumar R., Prajith Prabakar   +5 more
wiley   +1 more source

Real time road scene classification and enhancement for driver assistance under adverse weather. [PDF]

Sci Rep
Anoop PP, Deivanathan R.
europepmc   +1 more source