Results 31 to 40 of about 27,763,422 (276)

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Automated Denoising Technique for Random Input Signals using Empirical Mode Decomposition (EMD)-Stabilization Diagram

MATEC Web of Conferences, 2019
The present paper deals with the novel approach of filtering technique using hybrid of empirical mode decomposition technique with stabilization diagram, that autonomously implemented within Matlab.
Hasan M. Danial A., Ahmad Z. A. B., Leong M. Salman, Hee L. M.   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Modal Identification Method of Offshore Wind Turbine Tower Based on SSI and FSDPC

Shock and Vibration
The structural health monitoring of offshore wind turbine towers is critical for ensuring their operational integrity. The condition of the tower structure is characterized by its modal parameters, which serve as effective health indicators.
Lele Li, Yumin Liu, Lei Zhang, Mei Kong, Xiaojie Tian   +4 more
doaj   +1 more source

Automated Modal Analysis Using Stochastic Subspace Identification and Field Monitoring Data

Applied Sciences
The accurate identification of modal parameters is essential for structural health monitoring (SHM), as it provides critical insights into the presence of damage or degradation within the structure.
Shieh-Kung Huang, Zong-Zhi Lai, Hoong-Pin Lee, Yen-Yu Yang   +3 more
doaj   +1 more source

Application of Discrete Wavelet Transform for Condition Monitoring and Fault Detection in Wind Turbine Blades: An Experimental Study [PDF]

Engineering and Technology Journal
Effective structural monitoring maximizes efficiency in wind turbines, a crucial renewable energy asset. Using advanced condition monitoring techniques is crucial for reliability.
Ahmed Ogaili, Mohsin Hamzah, Alaa Jaber, Ehsan Ghane   +3 more
doaj   +1 more source

Comparative operational modal analysis: Application of a semi-active vibration absorber to a manufacturing machine

, 2022
8 S.This paper presents a semi-active vibration absorber concept and its implementa-tion on a manufacturing machine for a vibration reduction scheme.
Melz, T., Atzrodt, H., Schmidt, M., Rue, G. de, Sabirin, C.R.   +4 more
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Data Cleansing for Robust Modal Parameter Tracking in Vibration-Based Structural Health Monitoring

Infrastructures
Vibration-based Structural Health Monitoring (SHM) exploits automated Operational Modal Analysis (OMA) to track changes in modal parameters over time for subsequent statistical pattern recognition and anomaly detection.
Carlo Rainieri, Santiago Gómez Molina, Ilenia Rosati, Alessio De Corso   +3 more
doaj   +1 more source