Results 41 to 50 of about 27,763,422 (276)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Operational modal analysis of low frequency surface waves in Lakes and reservoirs

, 2019
Wind driven oscillations of water surfaces (surface seiches) are a key driver of ecological fluxes, such as of oxygen and nutrients, within lakes and reservoirs.
Bouffard, Damien (author), Wain, Danielle (author), Reynolds, Thomas (author), Schladow, Geoffrey (author), Wynne, Zachariah (author)   +4 more
core   +1 more source

Bridge Health Identification in the Era of Intelligent Infrastructure: A Modal- and AI-Centric Perspective

Eng
This paper presents a comprehensive review of bridge health identification (BHI) within the emerging paradigm of intelligent infrastructure, with a particular focus on modal analysis and artificial intelligence (AI)-driven methodologies.
Hasan Mostafaei, Yasaman Anisi, Hadi Bahmani, Mahdi Ghamami   +3 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Operational modal analysis with non stationnary inputs [PDF]

, 2013
Operational modal analysis (OMA) techniques enable the use of in-situ and uncontrolled vibrations to be used to lead modal analysis of structures. In reality operational vibrations are a combination of numerous excitations sources that are much more ...
Michon, Guilhem, Morlier, Joseph, Coulange, Baptiste, Gouache, Thibault   +3 more
core  

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Quantification of modal mineralogy in molybdenite-bearing drill-core samples by laser-induced breakdown spectroscopy

Heliyon
Quantification of modal mineralogy in drill-core samples is crucial for understanding the geology and metal deportment in a mining operation. This study assesses conventional procedures to quantify modal mineralogy, that includes an initial drill-core ...
Jonnathan Álvarez, Germán Velásquez, Iván Arévalo, Jorge Yáñez, Claudio Sandoval-Muñoz, Benjamín Sepúlveda   +5 more
doaj   +1 more source

Development and application of a multi-modal task analysis to support intelligent tutoring of complex skills

International Journal of STEM Education, 2018
Background Contemporary work in the design and development of intelligent training systems employs task analysis (TA) methods for gathering knowledge that is subsequently encoded into task models.
Anna Skinner, David Diller, Rohit Kumar, Jan Cannon-Bowers, Roger Smith, Alyssa Tanaka, Danielle Julian, Ray Perez   +7 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source