Results 61 to 70 of about 3,868,631 (298)

A New Approach for Automated Feature Selection

open access: yes2018 IEEE International Conference on Big Data (Big Data), 2018
Feature selection or variable selection is an important step in different machine learning tasks. In a traditional approach, users specify the amount of features, which shall be selected. Afterwards, algorithm select features by using scores like the Joint Mutual Information (JMI).
Andreas Gocht   +2 more
openaire   +3 more sources

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

A Model and Criteria for the Selection of Components for an Automated Greenhouse System

open access: yesЭкономика и управление, 2019
The present study solves the problem of automation of greenhouse complexes in the context of resource minimization. Aim. The study aims to improve the efficiency of decision support in the selection of components for an automated protected cultivation ...
Sergey A. Ivanov
doaj  

Automated affinity selection for rapid discovery of peptide binders

open access: yes, 2021
This work reports an automated affinity selection-mass spectrometry (AS-MS) approach amenable to both de novo peptide binder discovery and affinity maturation of known binders in a high-throughput and selective manner.
Li, Chengxi   +9 more
core   +1 more source

Automated detection of the CT-angiography spot sign in acute intracerebral hemorrhage

open access: yesFrontiers in Radiology
Early hematoma expansion is a major determinant of outcome after intracerebral hemorrhage (ICH). The CTA spot sign predicts hematoma expansion and poor outcome but requires specialized expertise for interpretation. Automated detection facilitates imaging-
Dar Dowlatshahi   +5 more
doaj   +1 more source

Automated Resolution Selection for Image Segmentation

open access: yesCoRR, 2016
It is well-known in image processing that computational cost increases rapidly with the number and dimensions of the images to be processed. Several fields, such as medical imaging, routinely use numerous very large images, which might also be 3D and/or captured at several frequency bands, all adding to the computational expense.
Fares S. Al-Qunaieer   +2 more
openaire   +2 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

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