Results 71 to 80 of about 1,384,700 (276)

Targeting the ATX‐LPA Axis Overcomes TKI Resistance and Immunosuppression in Renal Cell Carcinoma via Dual Inhibition of AKT/mTOR and TBK1/IRF3 Pathways

Advanced Science, EarlyView.
ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo, Hansen Lin, Haoqian Feng, Lei Tan, Xi Liu, Yong Huang, Junjie Cen, Jiajie Chen, Xinwei Zhou, Mingjie Lin, Wuyuan Liao, Zheyu Ai, Minyu Chen, Yinghan Wang, Wei Chen, Junhang Luo, Yanping Liang   +16 more
wiley   +1 more source

ORBIT‐AMD: Ordinal Risk, Bilateral Imaging, and Trajectory Learning for Age‐Related Macular Degeneration in Multi‐Cohorts

Advanced Science, EarlyView.
Eligibility flow and real‐world AMD burden in the UKB retinal imaging cohort and TMUEH external‐validation cohort. Overview of the ORBIT‐AMD architecture, integrating retinal representation pretraining, bilateral eye‐graph modeling and concept bottleneck learning to support ordered risk, bilateral context, interpretable lesion concepts, longitudinal ...
Xuehao Cui, Dejia Wen, Patrick Yu‐Wai‐Man, Xiaorong Li   +3 more
wiley   +1 more source

Somatic Surveillance: Corporeal Control through Information Networks

, 2002
Somatic surveillance is the increasingly invasive technological monitoring of and intervention into body functions. Within this type of surveillance regime, bodies are recast as nodes on vast information networks, enabling corporeal control through ...
Monahan, Torin, Wall, Tyler
core   +1 more source

The 'named person': surveillance and the wellbeing of children and young people in Scotland. [PDF]

, 2015
The Scottish Parliament’s ‘Children and Young People’ Bill has extended statutory responsibilities for the welfare of children to include their well-being.
Stoddart, Eric
core   +1 more source

A Dual‐Modal Wearable PPG Smartwatch with AI‐Enhanced Correction for High‐Accuracy and Continuous AF Burden Assessment

Advanced Science, EarlyView.
ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo, Jinglei Wang, Xin Wang, Han Feng, Yize Zhao, Fadong Li, Shaobin Wei, Le Zhou, Zixu Zhao, Songjie Chen, Xiangyi Kong, Jue Wang, Liu He, Shijun Xia, Xin Li, Junmeng Zhang, Xiaoxia Liu, Xueyuan Guo, Ning Zhou, Songnan Li, Chenxi Jiang, Ribo Tang, Caihua Sang, Deyong Long, Xin Du, Jianzeng Dong, Wenwu Zhu, Changsheng Ma   +27 more
wiley   +1 more source

Automating report generation for disease surveillance data using R Markdown: a case study on mosquito surveillance data

Zhongguo gonggong weisheng
This study proposes a method for automated report generation in disease control agencies using R Markdown and demonstrates the entire workflow from data collection, analysis, and visualization to report generation through a case study on mosquito ...
Chuangduan CHEN, Shu XIAO, Jianpeng XIAO, Ruipeng LU, Zuhua RONG, Weilin ZENG, Jianguo ZHAO, Dexin GONG   +7 more
doaj   +1 more source

Automated health surveillance.

Family medicine, 1989
A successful health maintenance program requires physicians interested in and knowledgeable about the appropriate health surveillance actions to pursue. But even well-informed physicians need help transforming good intentions into effective health surveillance.
B, Block, J A, Brennan
openaire   +1 more source

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

Advanced Science, EarlyView.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang, Ting Wu, Feizuo Wang, Boyang Wang, Xin Yu Wong, Senfeng Zhang, Shengsheng Ma, Yao Liu, Fangyao Yao, Zhifeng Zeng, Siyuan Yang, Kunming Liu, Qi Wang, Yilong Wang, Yunxiang Zang, Xiaolong Wang, Xingxu Huang, Shao Li, Quanquan Ji, Tao Hu, Chunyi Hu   +20 more
wiley   +1 more source

Systematic scoping review of automated systems for the surveillance of healthcare-associated bloodstream infections related to intravascular catheters

Antimicrobial Resistance and Infection Control
Introduction Intravascular catheters are crucial devices in medical practice that increase the risk of healthcare-associated infections (HAIs), and related health-economic adverse outcomes.
Nasim Lotfinejad, Jean-Marie Januel, Sarah Tschudin-Sutter, Peter W Schreiber, Bruno Grandbastien, Lauro Damonti, Elia Lo Priore, Alexandra Scherrer, Stephan Harbarth, Gaud Catho, Niccolò Buetti, Swissnoso Group   +11 more
doaj   +1 more source

Modern Slavery in the Gig Economy: Analysing the Exploitation of Gig and Freelance Workers through AI-Driven Communication Strategies and Automated Surveillance

International Journal of Management, Knowledge and Learning
Purpose: In modern corporate slavery, especially in Gig and freelance there is a significant gap concerning the critical analysis of AI-driven communication technologies and automated surveillance instruments in continued exploitation. This article aims
Ioseb Gabelaia, Ramunė Bagočiūnaitė, Viktorija Navickienė   +2 more
doaj   +1 more source