Results 111 to 120 of about 18,507,454 (305)
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Automated inspection using database technology within the aerospace industry [PDF]
Many manufacturing processes have become fully automated resulting in high production volumes. However, this is not the case for inspection. Shortening the inspection times in manufacturing industry using the available information resources can result ...
Tiwari, Ashutosh +3 more
core +2 more sources
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
Herein, RATSGO (Real-time Automated Training and Sensing for Gas Odor), a fully automated live-animal olfactory training platform, for the detection of GBL as a sexual assault-facilitating drug is reported.
Miha Kim +4 more
doaj +1 more source
Automated Traffic Control System for Emergency Services [PDF]
This project aims at creating an effective automated traffic control system to prevent ambulances/emergency service vehicles from getting caught up in traffic, there by decreasing hindrances to vital services both in regular and critical situations.
M Prasanth
core
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan +14 more
wiley +1 more source
Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer +11 more
wiley +1 more source
The paper deals with up-to-date questions concerning the effective introduction of the newest information technologies, system complexes and computer programs into management of general education establishment.
Zoya V. Savchenko
doaj

