Results 61 to 70 of about 1,091,165 (230)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Automatic treebank-based acquisition of Arabic LFG dependency structures [PDF]

, 2009
A number of papers have reported on methods for the automatic acquisition of large-scale, probabilistic LFG-based grammatical resources from treebanks for English (Cahill and al., 2002), (Cahill and al., 2004), German (Cahill and al., 2003), Chinese ...
Attia, Mohammed, Tounsi, Lamia, van Genabith, Josef   +2 more
core   +3 more sources

Comparison of manual, machine learning, and hybrid methods for video annotation to extract parental care data

Journal of Avian Biology
Measuring parental care behaviour in the wild is central to the study of animal ecology and evolution, but it is often labour‐ and time‐intensive. Efficient open‐source tools have recently emerged that allow animal behaviour to be quantified from videos ...
Alex Hoi Hang Chan, Jingqi Liu, Terry Burke, William D. Pearse, Julia Schroeder   +4 more
doaj   +1 more source

Gimme The Context: Context-driven automatic semantic annotation with C-PANKOW [PDF]

, 2005
Cimiano P, Ladwig G, Staab S. Gimme The Context: Context-driven automatic semantic annotation with C-PANKOW. In: Ellis A, Hagino T, eds. Proceedings of the 14th international conference on World Wide Web, WWW 2005.
Hagino, Tatsuya, Staab, Steffen, Ladwig, Günter, Cimiano, Philipp ; https://orcid.org/, Ellis, Allan   +4 more
core  

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Semantic spaces revisited: investigating the performance of auto-annotation and semantic retrieval using semantic spaces

, 2008
Semantic spaces encode similarity relationships between objects as a function of position in a mathematical space. This paper discusses three different formulations for building semantic spaces which allow the automatic-annotation and semantic retrieval ...
Lewis, Paul, Nixon, Mark, Samangooei, Sina, Hare, Jonathan   +3 more
core   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source