Results 81 to 90 of about 262,026 (340)

Automatic protein clustering as a basis of automatic annotation [PDF]

open access: yesNature Precedings, 2010
AbstractDevelopment of new generation sequencers enabled genome sequencing feasible for every organism in a laboratory. A typical data flow of de novo seuqencing includes (1) assembly of sequence reads, (2) estimation of open reading frames, (3) annotation of proteins, and (4) finding RNA genes.
openaire   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

open access: yesMolecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen   +17 more
wiley   +1 more source

A text-based approach to the ImageCLEF 2010 photo annotation task [PDF]

open access: yes, 2010
The challenges of searching the increasingly large collections of digital images which are appearing in many places mean that automated annotation of images is becoming an important task. We describe our participation in the ImageCLEF 2010 Visual Concept
Jones, Gareth J.F.   +2 more
core   +2 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

The GATO gene annotation tool for research laboratories

open access: yesBrazilian Journal of Medical and Biological Research, 2005
Large-scale genome projects have generated a rapidly increasing number of DNA sequences. Therefore, development of computational methods to rapidly analyze these sequences is essential for progress in genomic research.
A. Fujita   +4 more
doaj   +1 more source

Fuzzy Neighbor Voting for Automatic Image Annotation [PDF]

open access: yesJournal of Electrical and Computer Engineering Innovations, 2016
With quick development of digital images and the availability of imaging tools, massive amounts of images are created. Therefore, efficient management and suitable retrieval, especially by computers, is one of themost challenging fields in image ...
V. Maihami, F. Yaghmaee
doaj   +1 more source

Modern tools for annotation of small genomes of non-model eukaryotes [PDF]

open access: yesarXiv, 2021
Nowadays, due to the increasing amount of experimental data obtained by sequencing, the most interest is focused on determining the functions and characteristics of its individual parts of the genome instead of determining the nucleotide sequence of the genome.
arxiv  

Prediction of Metabolic Pathways Involvement in Prokaryotic UniProtKB Data by Association Rule Mining

open access: yes, 2016
The widening gap between known proteins and their functions has encouraged the development of methods to automatically infer annotations. Automatic functional annotation of proteins is expected to meet the conflicting requirements of maximizing ...
Boudellioua, Imane   +4 more
core   +2 more sources

A framework for evaluating automatic image annotation algorithms [PDF]

open access: yes, 2010
Several Automatic Image Annotation (AIA) algorithms have been introduced recently, which have been found to outperform previous models. However, each one of them has been evaluated using either different descriptors, collections or parts of collections ...
A.W.M. Smeulders   +12 more
core   +2 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

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