Results 41 to 50 of about 257,984 (281)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
An Automatic Parking Algorithm Design Using Multi-Objective Particle Swarm Optimization
IEEE Access, 2023 In this article, an automatic vehicle parallel parking algorithm, consisting of path planning, controller design, and state estimation is developed.
Saeede Mohammadi Daniali +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
TITAN automatic spatial quality control of meteorological in-situ observations [PDF]
Advances in Science and Research, 2020 In science, poor quality input data will invariably lead to faulty conclusions, as in the spirit of the saying “garbage in, garbage out”. Atmospheric sciences make no exception and correct data is crucial to obtain a useful representation of the real ...
L. Båserud +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
A Multiagent System for Edge Detection and Continuity Perception on Fish Otolith Images
EURASIP Journal on Advances in Signal Processing, 2002 We present an algorithm for fish otolith growth ring detection using a multiagent system. Up to now, the identification of growth rings, for age estimation, is routinely achieved by human readers, but this task is tedious and depends on the reader ...
Troadec Herve +4 more
doaj +1 more source
Automatic Horizon Picking Using Multiple Seismic Attributes and Markov Decision Process
Remote Sensing, 2023 Picking the reflection horizon is an important step in velocity inversion and seismic interpretation. Manual picking is time-consuming and no longer suitable for current large-scale seismic data processing.
Chengliang Wu +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Automatic continuity via analytic thinning [PDF]
Proceedings of the American Mathematical Society, 2009 We use Choquet’s analytic capacitability theorem and the Kestelman-Borwein-Ditor theorem (on the inclusion of null sequences by translation) to derive results on ‘analytic automaticity’ – for instance, a stronger common generalization of the Jones/Kominek theorems that an additive function whose restriction is continuous/bounded on an analytic set
Bingham, N. H., Ostaszewski, A. J.
openaire +2 more sources